KEGG   Homo sapiens (human): 4350
Entry
4350              CDS       T01001                                 
Symbol
MPG, AAG, ADPG, APNG, CRA36.1, MDG, Mid1, PIG11, PIG16, anpg
Name
(RefSeq) N-methylpurine DNA glycosylase
  KO
K03652  DNA-3-methyladenine glycosylase [EC:3.2.2.21]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03410  Base excision repair
Network
nt06504  Base excision repair
  Element
N01433  Base excision and strand cleavage by monofunctional glycosylase
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03410 Base excision repair
    4350 (MPG)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:hsa03400]
    4350 (MPG)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.2  Hydrolysing N-glycosyl compounds
    3.2.2.21  DNA-3-methyladenine glycosylase II
     4350 (MPG)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA glycosylases
     4350 (MPG)
 Prokaryotic type
     4350 (MPG)
SSDB
Motif
Pfam: Pur_DNA_glyco
Other DBs
NCBI-GeneID: 4350
NCBI-ProteinID: NP_002425
OMIM: 156565
HGNC: 7211
Ensembl: ENSG00000103152
UniProt: P29372 Q1W6H1
Structure
Position
16:77007..85846
AA seq 298 aa
MVTPALQMKKPKQFCRRMGQKKQRPARAGQPHSSSDAAQAPAEQPHSSSDAAQAPCPRER
CLGPPTTPGPYRSIYFSSPKGHLTRLGLEFFDQPAVPLARAFLGQVLVRRLPNGTELRGR
IVETEAYLGPEDEAAHSRGGRQTPRNRGMFMKPGTLYVYIIYGMYFCMNISSQGDGACVL
LRALEPLEGLETMRQLRSTLRKGTASRVLKDRELCSGPSKLCQALAINKSFDQRDLAQDE
AVWLERGPLEPSEPAVVAAARVGVGHAGEWARKPLRFYVRGSPWVSVVDRVAEQDTQA
NT seq 897 nt   +upstreamnt  +downstreamnt
atggtcacccccgctttgcagatgaagaaaccaaagcagttttgccgacggatggggcaa
aagaagcagcgaccagctagagcagggcagccacacagctcgtccgacgcagcccaggca
cctgcagagcagccacacagctcgtccgatgcagcccaggcaccttgccccagggagcgc
tgcttgggaccgcccaccactccgggcccataccgcagcatctatttctcaagcccaaag
ggccaccttacccgactggggttggagttcttcgaccagccggcagtccccctggcccgg
gcatttctgggacaggtcctagtccggcgacttcctaatggcacagaactccgaggccgc
atcgtggagaccgaggcatacctggggccagaggatgaagccgcccactcaaggggtggc
cggcagaccccccgcaaccgaggcatgttcatgaagccggggaccctgtacgtgtacatc
atttacggcatgtacttctgcatgaacatctccagccagggggacggggcttgcgtcttg
ctgcgagcactggagcccctggaaggtctggagaccatgcgtcagcttcgcagcaccctc
cggaaaggcaccgccagccgtgtcctcaaggaccgcgagctctgcagtggcccctccaag
ctgtgccaggccctggccatcaacaagagctttgaccagagggacctggcacaggatgaa
gctgtatggctggagcgtggtcccctggagcccagtgagccggctgtagtggcagcagcc
cgggtgggcgtcggccatgcaggggagtgggcccggaaacccctccgcttctatgtccgg
ggcagcccctgggtcagtgtggtcgacagagtggctgagcaggacacacaggcctga

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