KEGG   Homo sapiens (human): 438
Entry
438               CDS       T01001                                 
Symbol
ASMT, ASMTY, HIOMT, HIOMTY
Name
(RefSeq) acetylserotonin O-methyltransferase
  KO
K00543  acetylserotonin O-methyltransferase [EC:2.1.1.4]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00380  Tryptophan metabolism
hsa01100  Metabolic pathways
Module
hsa_M00037  Melatonin biosynthesis, animals, tryptophan => serotonin => melatonin
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00380 Tryptophan metabolism
    438 (ASMT)
Enzymes [BR:hsa01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.4  acetylserotonin O-methyltransferase
     438 (ASMT)
SSDB
Motif
Pfam: Methyltransf_2 Dimerisation2 Methyltransf_12 Methyltransf_25 Methyltransf_31 Methyltransf_23
Other DBs
NCBI-GeneID: 438
NCBI-ProteinID: NP_001164509
OMIM: 300015 402500
HGNC: 750
Ensembl: ENSG00000196433 ENSG00000292336
UniProt: P46597
Structure
Position
X:1615059..1643081, Y:1615059..1643081
AA seq 373 aa
MGSSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGT
ELLLDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHL
ADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVF
PLMCDLGGTWIKLETIILSKLSQGQKTKHRVFSLIGGAGALAKECMSLYPGCKITVFDIP
EVVWTAKQHFSFQEEEQIDFQEGDFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHT
CKPGGGILVIESLLDEDRRGPLLTQLYSLNMLVQTEGQERTPTHYHMLLSSAGFRDFQFK
KTGAIYDAILARK
NT seq 1122 nt   +upstreamnt  +downstreamnt
atgggatcctcagaggaccaggcctatcgcctccttaatgactacgccaacggcttcatg
gtgtcccaggttctcttcgccgcctgcgagctgggcgtgtttgaccttctcgccgaggcc
ccagggcccctggacgtggcggcagtggctgcaggtgtgagggccagcgcccatgggaca
gagctcctgctggacatctgtgtgtccctgaagctgctgaaagtggagacgaggggagga
aaagctttctatcgaaacacagagctgtccagcgactacctgaccacggtcagcccgacg
tcacaatgcagcatgctgaagtacatgggcaggaccagctaccggtgctggggccacctg
gcagacgccgtgagagaaggaaggaaccagtacctggagacgtttggcgttcccgctgaa
gagctttttacggccatctacaggtccgagggcgagcggctacagttcatgcaagctctg
caggaggtctggagcgtcaacgggagaagcgtgctgaccgcctttgacctgtcagtgttc
ccacttatgtgtgaccttggtgggacatggataaagctggaaaccatcattctcagcaaa
ctatcgcaaggacagaaaaccaaacaccgcgtgttctcactcataggtggggctggagct
ctggctaaggaatgcatgtctctgtaccctggatgtaagatcaccgtttttgacatccca
gaagtggtgtggacggcaaagcagcacttctcattccaggaggaagaacagattgacttc
caggaaggggatttcttcaaagaccctcttccggaagctgatctgtacatcctggccagg
gtcctccatgactgggcagacggaaagtgctcacacctgctggagaggatctaccacact
tgcaagccaggtggtggcattctggtaattgaaagcctcctggatgaagacaggcgaggt
cctctgctcacgcagctctactctctgaacatgcttgtgcagacggaagggcaggagagg
acccccacccactaccacatgctcctctcttctgctggcttcagagacttccagtttaag
aaaacaggagccatttatgatgccattttagccaggaaataa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (2)   
   KEGG MODULE (1)   
Disease (2)   
   OMIM (2)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (2)   
   RIKEN BRC-DNA (6)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (22)   
   RefSeq(nuc) (4)   
   GenBank (9)   
   EMBL (9)   
3D Structure (2)   
   PDB (2)   
Protein domain (6)   
   Pfam (6)   
All databases (73)   

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