KEGG   Homo sapiens (human): 4582
Entry
4582              CDS       T01001                                 
Symbol
MUC1, ADMCKD, ADMCKD1, ADTKD2, CA_15-3, CD227, Ca15-3, EMA, H23AG, KL-6, MAM6, MCD, MCKD, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM
Name
(RefSeq) mucin 1, cell surface associated
  KO
K06568  mucin-1
Organism
hsa  Homo sapiens (human)
Disease
H00541  Autosomal dominant tubulointerstitial kidney disease
H02012  Medullary cystic kidney disease
Drug target
Arcitumomab: D02977
Emepepimut-S: D09895
Technetium (99mTc) arcitumomab: D06028
Yttrium Y 90 clivatuzumab tetraxetan: D09700
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    4582 (MUC1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    4582 (MUC1)
   04090 CD molecules [BR:hsa04090]
    4582 (MUC1)
Membrane trafficking [BR:hsa04131]
 Others
  Mucins
   Membrane bound mucins
    4582 (MUC1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of breast milk
   4582 (MUC1)
  Exosomal proteins of breast cancer cells
   4582 (MUC1)
  Exosomal proteins of bladder cancer cells
   4582 (MUC1)
CD molecules [BR:hsa04090]
 Proteins
  4582 (MUC1)
SSDB
Motif
Pfam: SEA Stevor Collectrin
Other DBs
NCBI-GeneID: 4582
NCBI-ProteinID: NP_001191215
OMIM: 158340
HGNC: 7508
Ensembl: ENSG00000185499
UniProt: P15941
Structure
Position
1:complement(155185824..155192915)
AA seq 484 aa
MTPGTQSPFFLLLLLTVLTATTAPKPATVVTGSGHASSTPGGEKETSATQRSSVPSSTEK
NAVSMTSSVLSSHSPGSGSSTTQGQDVTLAPATEPASGSAATWGQDVTSVPVTRPALGST
TPPAHDVTSAPDNKPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDNRPALGST
APPVHNVTSASGSASGSASTLVHNGTSARATTTPASKSTPFSIPSHHSDTPTTLASHSTK
TDASSTHHSTVPPLTSSNHSTSPQLSTGVSFFFLSFHISNLQFNSSLEDPSTDYYQELQR
DISEMFLQIYKQGGFLGLSNIKFRPGSVVVQLTLAFREGTINVHDVETQFNQYKTEAASR
YNLTISDVSVSDVPFPFSAQSGAGVPGWGIALLVLVCVLVALAIVYLIALAVCQCRRKNY
GQLDIFPARDTYHPMSEYPTYHTHGRYVPPSSTDRSPYEKVSAGNGGSSLSYTNPAVAAT
SANL
NT seq 1455 nt   +upstreamnt  +downstreamnt
atgacaccgggcacccagtctcctttcttcctgctgctgctcctcacagtgcttacagct
accacagcccctaaacccgcaacagttgttacgggttctggtcatgcaagctctacccca
ggtggagaaaaggagacttcggctacccagagaagttcagtgcccagctctactgagaag
aatgctgtgagtatgaccagcagcgtactctccagccacagccccggttcaggctcctcc
accactcagggacaggatgtcactctggccccggccacggaaccagcttcaggttcagct
gccacctggggacaggatgtcacctcggtcccagtcaccaggccagccctgggctccacc
accccgccagcccacgatgtcacctcagccccggacaacaagccagccccgggctccacc
gcccccccagcccacggtgtcacctcggccccggacaccaggccggccccgggctccacc
gcccccccagcccatggtgtcacctcggccccggacaacaggcccgccttgggctccacc
gcccctccagtccacaatgtcacctcggcctcaggctctgcatcaggctcagcttctact
ctggtgcacaacggcacctctgccagggctaccacaaccccagccagcaagagcactcca
ttctcaattcccagccaccactctgatactcctaccacccttgccagccatagcaccaag
actgatgccagtagcactcaccatagcacggtacctcctctcacctcctccaatcacagc
acttctccccagttgtctactggggtctctttctttttcctgtcttttcacatttcaaac
ctccagtttaattcctctctggaagatcccagcaccgactactaccaagagctgcagaga
gacatttctgaaatgtttttgcagatttataaacaagggggttttctgggcctctccaat
attaagttcaggccaggatctgtggtggtacaattgactctggccttccgagaaggtacc
atcaatgtccacgacgtggagacacagttcaatcagtataaaacggaagcagcctctcga
tataacctgacgatctcagacgtcagcgtgagtgatgtgccatttcctttctctgcccag
tctggggctggggtgccaggctggggcatcgcgctgctggtgctggtctgtgttctggtt
gcgctggccattgtctatctcattgccttggctgtctgtcagtgccgccgaaagaactac
gggcagctggacatctttccagcccgggatacctaccatcctatgagcgagtaccccacc
taccacacccatgggcgctatgtgccccctagcagtaccgatcgtagcccctatgagaag
gtttctgcaggtaatggtggcagcagcctctcttacacaaacccagcagtggcagccact
tctgccaacttgtag

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Disease (4)   
   KEGG DISEASE (2)   
   OMIM (2)   
Drug (4)   
   KEGG DRUG (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (29)   
   KEGG ORTHOLOGY (1)   
   RefGene (22)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (23)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (21)   
DNA sequence (229)   
   RefSeq(nuc) (23)   
   GenBank (103)   
   EMBL (103)   
3D Structure (17)   
   PDB (17)   
Protein domain (3)   
   Pfam (3)   
All databases (314)   

Download RDF
DBGET integrated database retrieval system