KEGG   Homo sapiens (human): 4636
Entry
4636              CDS       T01001                                 
Symbol
MYL5, MYLC2
Name
(RefSeq) myosin light chain 5
  KO
K12753  myosin regulatory light chain 5
Organism
hsa  Homo sapiens (human)
Pathway
hsa04360  Axon guidance
hsa04510  Focal adhesion
hsa04520  Adherens junction
hsa04670  Leukocyte transendothelial migration
hsa04810  Regulation of actin cytoskeleton
hsa04814  Motor proteins
hsa04820  Cytoskeleton in muscle cells
hsa05131  Shigellosis
hsa05132  Salmonella infection
Network
nt06181  Salmonella
nt06182  Shigella
  Element
N01074  Shigella IpaA to ITGA/B-RhoGEF-RhoA signaling pathway
N01130  Salmonella SopB to RhoA signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    4636 (MYL5)
   04520 Adherens junction
    4636 (MYL5)
  09142 Cell motility
   04814 Motor proteins
    4636 (MYL5)
   04820 Cytoskeleton in muscle cells
    4636 (MYL5)
   04810 Regulation of actin cytoskeleton
    4636 (MYL5)
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    4636 (MYL5)
  09158 Development and regeneration
   04360 Axon guidance
    4636 (MYL5)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    4636 (MYL5)
   05131 Shigellosis
    4636 (MYL5)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    4636 (MYL5)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Myosins
     4636 (MYL5)
SSDB
Motif
Pfam: EF-hand_7 EF-hand_6 EF-hand_1 EF-hand_8 EF-hand_5 EF-hand_4 EFhand_Ca_insen Lipoprotein_6 Caleosin AIF-1
Other DBs
NCBI-GeneID: 4636
NCBI-ProteinID: NP_002468
OMIM: 160782
HGNC: 7586
Ensembl: ENSG00000215375
UniProt: Q02045
Position
4:674542..682028
AA seq 173 aa
MASRKTKKKEGGALRAQRASSNVFSNFEQTQIQEFKEAFTLMDQNRDGFIDKEDLKDTYA
SLGKTNVKDDELDAMLKEASGPINFTMFLNLFGEKLSGTDAEETILNAFKMLDPDGKGKI
NKEYIKRLLMSQADKMTAEEVDQMFQFASIDVAGNLDYKALSYVITHGEEKEE
NT seq 522 nt   +upstreamnt  +downstreamnt
atggccagcaggaagaccaagaagaaggaagggggtgccctccgggcccagagagcctca
tccaatgtcttctccaactttgagcagactcagatccaggagttcaaggaggcattcaca
ctcatggatcagaaccgagatggcttcattgacaaggaggacctgaaggacacctatgcc
tccctgggcaagaccaacgtcaaggacgacgagctggacgccatgctcaaagaggcctcg
gggcccatcaacttcaccatgtttctgaacctgtttggggagaagctgagcggtaccgac
gccgaggagaccattcttaacgccttcaagatgctggacccggacgggaaagggaaaatc
aacaaggagtacatcaagcgtctgctgatgtcccaggctgacaagatgacggcggaagag
gtggaccagatgttccagttcgcctccatcgatgtggcgggcaacctggactacaaggcg
ctcagctacgtgatcacccacggggaggagaaggaggagtga

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