KEGG   Homo sapiens (human): 4644
Entry
4644              CDS       T01001                                 
Symbol
MYO5A, GS1, MYH12, MYO5, MYR12
Name
(RefSeq) myosin VA
  KO
K10357  myosin V
Organism
hsa  Homo sapiens (human)
Pathway
hsa04814  Motor proteins
hsa05130  Pathogenic Escherichia coli infection
Disease
H02022  Griscelli syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09142 Cell motility
   04814 Motor proteins
    4644 (MYO5A)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    4644 (MYO5A)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    4644 (MYO5A)
   04131 Membrane trafficking [BR:hsa04131]
    4644 (MYO5A)
   03029 Mitochondrial biogenesis [BR:hsa03029]
    4644 (MYO5A)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    4644 (MYO5A)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   Factors involved in mRNA localization
    Cargo complex
     4644 (MYO5A)
   mRNA cycle factors
    P-body specific factors
     4644 (MYO5A)
Membrane trafficking [BR:hsa04131]
 Others
  Actin-binding proteins
   Myosins
    4644 (MYO5A)
Mitochondrial biogenesis [BR:hsa03029]
 Mitochondrial quality control factors
  Mitochondrial dynamics
   Retention of mitochondria
    4644 (MYO5A)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Myosins
     4644 (MYO5A)
SSDB
Motif
Pfam: Myosin_head DIL IQ Csm1_N AAA_16 Myosin_N AAA_22 nSTAND3 DUF5382
Other DBs
NCBI-GeneID: 4644
NCBI-ProteinID: NP_000250
OMIM: 160777
HGNC: 7602
Ensembl: ENSG00000197535
UniProt: Q9Y4I1 Q9UES4
Structure
Position
15:complement(52307283..52529050)
AA seq 1855 aa
MAASELYTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELP
HLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYG
EDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYF
ATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMR
TYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVD
DAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIF
CDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVN
QALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKE
QIPWTLIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEK
PRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAIS
PTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRC
IKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVL
SDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGW
LLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAA
TIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMM
AKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSE
TEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQET
EQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQN
LLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRT
EEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAE
LEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELD
VRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNR
SSALDYHELNEDGELWLVYEGLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNR
QQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKI
GELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKEDEQKLVKNLILELKPRGV
AVNLIPGLPAYILFMCVRHADYLNDDQKVRSLLTSTINSIKKVLKKRGDDFETVSFWLSN
TCRFLHCLKQYSGEEGFMKHNTSRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVRVLENI
LQPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIADEGTYTLDSILRQLNSFHSVMCQHGM
DPELIKQVVKQMFYIIGAITLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSGA
KETLEPLIQAAQLLQVKKKTDDDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVSVSF
IRTIQMRLRDRKDSPQLLMDAKHIFPVTFPFNPSSLALETIQIPASLGLGFISRV
NT seq 5568 nt   +upstreamnt  +downstreamnt
atggctgcgtcggagctctacacaaagtttgccagggtttggatacctgatccagaggaa
gtctggaagtcagcagagctgctcaaagattataagccaggagataaagtcctcctgctt
cacctcgaggaaggaaaggatttggaataccatctagatccaaagaccaaggagctgcct
cacttacgaaatcctgacatacttgttggtgaaaatgacctcacagccctcagctatctt
catgagcctgctgtgctccataatctcagagtccgctttattgattccaaacttatttat
acgtattgtggtatagtcctagtagctataaatccctatgaacagctgcctatttatgga
gaagatattattaatgcatacagtggtcagaacatgggtgatatggatccacatatcttt
gcagtagctgaagaagcttacaagcaaatggccagagatgaacgaaatcagtccatcatc
gtaagtggagagtctggggcaggaaaaacagtctcagctaagtatgccatgcgatacttt
gcaactgtgagtggttctgccagtgaggccaatgtggaggaaaaggtcttggcctccaac
cccatcatggagtccattggaaatgctaaaacaaccaggaatgataatagcagccgtttt
gggaagtatattgagattggttttgataagagatatcgaatcattggtgccaatatgaga
acttatcttttagagaaatccagagtggtattccaggcagaagaggagagaaactatcat
atcttctatcagctttgtgcctcagcaaagttacctgaatttaaaatgctacgattagga
aatgcagataactttaattacacaaaacaaggaggcagtcctgtgattgaaggagtggat
gatgcaaaggagatggcacatactaggcaggcctgcactttgctaggaattagtgaatct
catcaaatgggaattttccgaatacttgctggcatccttcacttaggcaatgttggattt
acatcccgagatgcagacagctgcacaatacctcccaagcatgaacctctctgcatcttc
tgtgacctcatgggtgtggactatgaggagatgtgtcactggctctgccatcggaaactg
gctactgccacagagacatacatcaagcccatctccaagctgcaggccacgaatgcccgc
gatgctttggccaagcacatctatgccaagctctttaactggattgtagataatgtcaat
caggctctccattctgctgtcaaacagcactcttttattggtgtgctagacatttacgga
tttgaaacatttgagataaatagttttgaacagttttgcataaattatgcaaatgaaaaa
ctacagcaacaattcaatatgcatgtcttcaaattggagcaagaagaatatatgaaggaa
caaattccatggacactcatagatttttatgataatcagccttgtattaatcttatagaa
tcaaaactaggcattctagatttactggatgaggaatgcaagatgcctaaaggcacagat
gacacctgggcccaaaaattgtacaacacacatttgaacaaatgtgcactctttgaaaag
cctcgtctatcaaacaaagctttcatcatccaacattttgctgacaaagtggaataccag
tgtgaaggatttctcgaaaagaataaagacaccgtttttgaagaacaaattaaagttctt
aaatcaagcaagtttaagatgctaccagaactatttcaagatgatgagaaggccatcagt
ccaacttcagccacctcctcagggcgcacacccctcacacgaactcctgcaaagcccacc
aaaggcagaccaggccaaatggccaaagagcacaagaaaacagtggggcatcagttcaga
aactccctgcacctgcttatggagacactcaatgccactacccctcactatgtgcgctgt
atcaagcctaatgacttcaagttcccattcacgtttgatgagaagagggcagtgcagcag
ctgagagcatgtggtgtcctggaaaccatccgaatcagtgcggccggtttcccctcacgg
tggacttaccaagaatttttcagccgctaccgtgtcctaatgaagcagaaagatgtgctg
agtgacagaaagcaaacatgcaagaatgtgttagagaaactgatactggacaaggacaaa
taccagtttggtaagacaaagatctttttccgtgccggtcaagtggcctatctagaaaaa
ttgagagctgacaaactgagagctgcctgcatccggatccagaagaccatccgagggtgg
ctgctgagaaagaagtacctacgcatgcggaaggcagccatcaccatgcagagatacgtg
cggggctaccaggcccgatgctatgctaagtttctgcgcagaaccaaggcagcaaccatc
attcaaaagtactggcgcatgtatgtggtccgcaggaggtacaagattagacgagctgcc
actattgttcttcagtcttacttgcgaggcttcttggccagaaataggtatcgcaagata
ctccgtgagcacaaagcagtcatcattcagaagcgagtccggggctggctggcccgcaca
cactacaagaggagcatgcatgccatcatctaccttcagtgctgcttcaggcggatgatg
gccaagcgtgagctaaagaagctcaaaatcgaggctcgctcagtggagcgctataagaag
ctgcacatcggcatggagaacaagatcatgcagctgcagcgcaaagttgatgagcagaac
aaagactacaaatgccttgtggagaaactaaccaatctggaaggaatatacaactctgag
actgagaaactacgaagtgacttagaacgtcttcaactaagtgaagaggaagcgaaagtt
gccactgggcgggtccttagtctgcaggaagaaattgccaagctccggaaagacctggag
caaactcgttcagagaaaaaatgcattgaggaacatgcagatcgatacaaacaagaaaca
gagcagctggtatcaaatctgaaggaagaaaatactttgctgaagcaagaaaaagaagcc
ctcaatcaccgcatcgtgcagcaggctaaggagatgacagaaactatggagaagaagtta
gtagaagaaacgaaacaactggaactcgaccttaatgatgaaaggctgagatatcagaac
cttctgaatgagttcagtcgcctggaagaaagatatgatgacctcaaggaagagatgacc
cttatggtgcatgtgcctaagcctggacacaagagaacagactccacccacagcagcaac
gagtctgaatatatctttagctctgaaattgcagaaatggaagacattccatcaaggaca
gaggaaccaagtgagaagaaggtacctctggacatgtcattgttccttaagctccagaag
cgggtcacagagctggagcaggagaagcaggtgatgcaggatgagctggaccgcaaggag
gagcaggtgctccgcagcaaggccaaggaagaagaaagaccacaaattagaggtgcagaa
ctggaatatgagtcactcaagcgtcaagaactagaatcagaaaacaaaaaactgaagaat
gagctaaatgagttgcgcaaggccctcagtgagaaaagtgccccagaggtgaccgcccca
ggtgcacctgcctaccgtgtcctcatggagcagctgacctctgtgagcgaggagcttgat
gtccgcaaggaggaagtcctcatcttaaggtctcaactggtgagccagaaagaggccatc
caacccaaggatgacaagaatacaatgacagattccacaatacttttggaagatgtacaa
aaaatgaaagataaaggtgaaatagcacaagcatacattggtttgaaagaaacaaataga
tcatctgctctggattaccatgagttgaatgaggatggagagctgtggctggtttatgaa
gggttaaaacaagccaacaggctcctggaatcccagctgcagtcacagaagaggagccat
gagaatgaggccgaggccctccgtggggagatccagagcctgaaggaggagaacaaccga
cagcagcagctgctggcccagaacctgcagctgcccccagaggcccgcattgaggccagc
ctgcagcacgagatcacccggctgaccaacgaaaacttggatttgatggaacaacttgaa
aaacaggataagacggtccgtaaactgaaaaaacaactgaaagtatttgccaaaaaaatt
ggcgaactagaagtgggccagatggagaacatatccccaggacagatcattgatgaaccc
atccgaccagtcaacattcccaggaaagaaaaggatttccaagggatgctggaatacaag
aaggaggatgagcaaaaacttgttaagaacctgattctggaactgaagccacgtggtgta
gcagtcaatttgattccaggattaccggcatatatcctgttcatgtgtgttcgacatgct
gactacctgaatgatgatcagaaagtaaggtcgttgctaacatcaacaattaacagcatc
aaaaaagtattgaagaaaagaggtgatgattttgaaaccgtctccttctggctctctaac
acatgccgatttttgcactgcttgaaacagtacagtggagaagagggctttatgaagcac
aacacatctcgccagaatgaacactgcctcaccaattttgacctggctgagtatcggcag
gtgctgagtgacttggccattcagatctaccagcagctcgtgcgggtgttagagaacatc
cttcagccaatgattgtctcaggcatgctggaacatgaaacgattcagggcgtgtctggg
gtgaagcccacagggttgagaaagcgaacctccagtatcgccgatgagggcacctacaca
ctggactccatcctccggcagctcaactccttccactcggtcatgtgtcagcatggcatg
gaccctgaactgatcaagcaggtggtcaagcagatgttctacatcataggggccatcacc
ctgaacaaccttctcctgcggaaggacatgtgctcctggagtaaaggcatgcagatcagg
tacaatgtcagtcaactggaagaatggctgcgtgacaagaatctgatgaatagtggggct
aaagaaaccctggaacctctcattcaggctgctcaacttttgcaagtgaaaaagaaaaca
gatgatgatgcagaagccatttgttctatgtgcaatgctttaactactgcccagattgtg
aaagtgttgaatttgtatactccagttaatgagtttgaagaaagagtctctgtgtcgttc
attcgtactatacagatgcgtttacgagacaggaaagactctccccagctgctcatggat
gctaaacacatctttcctgtcacctttcctttcaacccatcttccctcgcactagaaacc
atccagattccagccagcctcggcctgggcttcatttcacgggtctga

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   RefGene (14)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (21)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (18)   
DNA sequence (56)   
   RefSeq(nuc) (18)   
   GenBank (19)   
   EMBL (19)   
3D Structure (7)   
   PDB (7)   
Protein domain (9)   
   Pfam (9)   
All databases (124)   

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