KEGG   Homo sapiens (human): 4660
Entry
4660              CDS       T01001                                 
Symbol
PPP1R12B, MYPT2, PP1bp55
Name
(RefSeq) protein phosphatase 1 regulatory subunit 12B
  KO
K12329  protein phosphatase 1 regulatory subunit 12B
Organism
hsa  Homo sapiens (human)
Pathway
hsa04270  Vascular smooth muscle contraction
hsa04510  Focal adhesion
hsa04810  Regulation of actin cytoskeleton
hsa04921  Oxytocin signaling pathway
hsa05205  Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    4660 (PPP1R12B)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    4660 (PPP1R12B)
 09150 Organismal Systems
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    4660 (PPP1R12B)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    4660 (PPP1R12B)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    4660 (PPP1R12B)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    4660 (PPP1R12B)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     4660 (PPP1R12B)
SSDB
Motif
Pfam: PRKG1_interact Ank_2 Ank Ank_4 Ank_5 Ank_3
Other DBs
NCBI-GeneID: 4660
NCBI-ProteinID: NP_002472
OMIM: 603768
HGNC: 7619
Ensembl: ENSG00000077157
UniProt: O60237
Position
1:202348699..202592702
AA seq 982 aa
MAELEHLGGKRAESARMRRAEQLRRWRGSLTEQEPAERRGAGRQPLTRRGSPRVRFEDGA
VFLAACSSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQ
DNEGWTPLHAAASCGYLNIAEYFINHGASVGIVNSEGEVPSDLAEEPAMKDLLLEQVKKQ
GVDLEQSRKEEEQQMLQDARQWLNSGKIEDVRQARSGATALHVAAAKGYSEVLRLLIQAG
YELNVQDYDGWTPLHAAAHWGVKEACSILAEALCDMDIRNKLGQTPFDVADEGLVEHLEL
LQKKQNVLRSEKETRNKLIESDLNSKIQSGFFKNKEKMLYEEETPKSQEMEEENKESSSS
SSEEEEGEDEASESETEKEADKKPEAFVNHSNSESKSSITEQIPAPAQNTFSASSARRFS
SGLFNKPEEPKDESPSSWRLGLRKTGSHNMLSEVANSREPIRDRGSSIYRSSSSPRISAL
LDNKDKERENKSYISSLAPRKLNSTSDIEEKENRESAVNLVRSGSYTRQLWRDEAKGNEI
PQTIAPSTYVSTYLKRTPHKSQADTTAEKTADNVSSSTPLCVITNRPLPSTANGVTATPV
LSITGTDSSVEAREKRRSYLTPVRDEEAESLRKARSRQARQTRRSTQGVTLTDLQEAERT
FSRSRAERQAQEQPREKPTDTEGLEGSPEKHEPSAVPATEAGEGQQPWGRSLDEEPICHR
LRCPAQPDKPTTPASPSTSRPSLYTSSHLLWTNRFSVPDSESSETTTNTTTAKEMDKNEN
EEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSRLESG
GSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKL
QEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKVLTELK
SDNQRLKDENGALIRVISKLSK
NT seq 2949 nt   +upstreamnt  +downstreamnt
atggcggaactggagcacctaggagggaagcgggcagagtcggcgcgaatgcggcgggca
gagcagcttcggcgctggcggggctcgctgacagagcaggagcctgcggagcgacgaggc
gcggggcggcagccgctgaccaggcgcgggagccccagggtccgcttcgaggacggtgct
gtctttctggccgcctgctctagcggggacaccgacgaggtgagaaagcttctggcaaga
ggtgctgatatcaacacggtcaacgtggacggcttgacagccctgcaccaggcatgtatt
gatgaaaatttggacatggtgaagtttctggtggagaacagagccaatgtaaaccagcaa
gacaacgagggctggacaccccttcatgcagcagcttcctgtggctatctcaacatagca
gagtatttcattaatcacggagccagtgtaggtattgtcaatagtgaaggtgaagttccc
tctgaccttgcagaagagccagccatgaaggatcttcttctggagcaagtaaagaagcaa
ggagttgatctagagcagtcaagaaaagaagaagagcagcagatgttgcaggatgcccgc
cagtggctcaacagtgggaaaatagaggatgtgaggcaggctcgctcaggggctacagcc
cttcatgtggctgctgccaagggctactctgaagtcctcagacttttaattcaggctggc
tatgaactcaatgttcaggattatgatggctggactcccctccatgctgctgcacactgg
ggagtgaaggaggcttgctccatcctggcagaagcactttgtgacatggatattcgaaat
aaactgggccagacaccatttgatgtggctgatgagggtctcgtggagcatttggagttg
ctccagaagaagcagaatgtgcttcgaagtgaaaaggagacacggaataaactcattgag
tcagatctgaacagcaagattcagagtgggttctttaagaacaaagagaagatgctctat
gaggaggagacacctaagtcccaagaaatggaggaagaaaataaagaatctagtagctcc
agctcagaggaggaggaaggtgaagatgaagcttctgagtcagaaactgagaaggaggca
gataaaaagccagaagcctttgtcaatcattccaactctgaaagcaagagtagtatcaca
gagcagataccagcaccagctcaaaataccttctctgcctcttctgctaggaggttctct
tctggcctttttaacaagccagaagagcccaaagatgaatctccttcttcatggagattg
ggactgagaaaaactggcagccacaacatgctgagtgaggtggccaattccagggaacct
ataagggaccgaggctcttccatctatcgctcctcttcaagccctcggatttctgctcta
ctggacaacaaagataaggagagagaaaacaaaagctatattagttcactagcaccccgg
aagctcaacagcacaagtgatattgaagaaaaggagaacagagaatcagctgttaatcta
gtgaggagtggctcctatacccggcagctatggagggatgaagcaaaaggaaatgaaatc
ccacagacaattgctccctccacctatgtatcaacttacttgaaaaggactcctcacaaa
tcccaggccgacacaacagcagagaaaacagcagacaatgtctcttctagcaccccgctc
tgtgtgatcaccaatcgccctcttcctagcactgccaatggggttacagctactcctgtg
ctctccattactggaacagattcctctgtggaagccagggagaagaggaggtcctatctg
actcctgtacgggatgaggaagcagagtctttacggaaagcacgctccagacaagctcgg
cagacacgaaggtctactcaaggtgtcaccctaacagaccttcaagaagcagaaaggaca
ttcagccggtcgagggcagagaggcaagctcaggagcagcctcgtgagaagcccacagac
actgaagggcttgaggggagccctgagaagcatgagccctcagcagttccagcaacagaa
gctggggagggccagcagccctggggcaggagtctggatgaagagcctatctgtcatcgc
ctgaggtgcccagctcagccagacaaacccaccacgccagcatctccttctacgtcaaga
ccctcactctacaccagttcccacctgctatggacaaatagattttcagtccctgattct
gagagttcagagactaccacaaacactacaactgcaaaggaaatggacaaaaatgagaat
gaagaagcagatttggatgagcagtcctctaagaggctgtccatccgagagaggaggcgg
cccaaggaacgacgaagaggcacaggcatcaatttctggacaaaggatgaggatgaaact
gatggctctgaagaggtcaaagaaacgtggcatgaaagactttctaggttggaatcggga
ggtagtaatcctacaaccagtgattcttacggtgaccgggcttcagcaagagcccgtcgg
gaggcccgggaggcccgcctagccaccctgaccagccgtgtagaagaagacagcaacaga
gattataaaaaactctatgagagtgctctgactgaaaaccaaaaactgaaaacaaaactt
caggaagcccagctagagctagcagatataaagtccaagcttgagaaggtggcccagcag
aaacaagaaaagacctctgaccgatcatcagtgctggagatggagaaacgggagaggcga
gccttggagcgcaaaatgtcagaaatggaggaagaaatgaaggtgttaacagaactgaaa
tccgacaaccagaggctgaaagatgaaaatggtgccctcatcagagtcatcagcaaactg
tccaagtag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (5)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (38)   
   KEGG ORTHOLOGY (1)   
   RefGene (31)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (26)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (24)   
DNA sequence (81)   
   RefSeq(nuc) (41)   
   GenBank (20)   
   EMBL (20)   
Protein domain (6)   
   Pfam (6)   
All databases (160)   

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