KEGG   Homo sapiens (human): 4684
Entry
4684              CDS       T01001                                 
Symbol
NCAM1, CD56, MSK39, NCAM
Name
(RefSeq) neural cell adhesion molecule 1
  KO
K06491  neural cell adhesion molecule
Organism
hsa  Homo sapiens (human)
Pathway
hsa03265  Virion - Ebolavirus and Lyssavirus
hsa04514  Cell adhesion molecules
hsa05020  Prion disease
Drug target
Lorvotuzumab mertansine: D09927
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03265 Virion - Ebolavirus and Lyssavirus
    4684 (NCAM1)
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    4684 (NCAM1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05020 Prion disease
    4684 (NCAM1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    4684 (NCAM1)
  09183 Protein families: signaling and cellular processes
   04515 Cell adhesion molecules [BR:hsa04515]
    4684 (NCAM1)
   04090 CD molecules [BR:hsa04090]
    4684 (NCAM1)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    4684 (NCAM1)
   00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:hsa00537]
    4684 (NCAM1)
Membrane trafficking [BR:hsa04131]
 Exocytosis
  Tethering complex
   Exocyst complex assembly proteins
    4684 (NCAM1)
Cell adhesion molecules [BR:hsa04515]
 Immunoglobulin superfamily
  NCAM1/2
   4684 (NCAM1)
CD molecules [BR:hsa04090]
 Proteins
  4684 (NCAM1)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate / Heparin
  Adhesion molecules of cell surface
   4684 (NCAM1)
Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:hsa00537]
 Others
  4684 (NCAM1)
SSDB
Motif
Pfam: I-set Ig_3 ig Ig_2 fn3 V-set C2-set_2 C1-set Ig_6 Ig_4 Ig_5 V-set_CD47 Adeno_E3_CR1 Pur_ac_phosph_N Collagen_bind_2
Other DBs
NCBI-GeneID: 4684
NCBI-ProteinID: NP_851996
OMIM: 116930
HGNC: 7656
Ensembl: ENSG00000149294
UniProt: P13591
Structure
Position
11:112961420..113278436
AA seq 858 aa
MLQTKDLIWTLFFLGTAVSLQVDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGE
KLTPNQQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMF
KNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIK
KTDEGTYRCEGRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGF
PEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATI
HLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKASWTRPE
KQETLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQG
PVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDS
ENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDQVEPYSSTAQVQFDEPEATGGVPI
LKYKAEWRAVGEEVWHSKWYDAKEASMEGIVTIVGLKPETTYAVRLAALNGKGLGEISAA
SEFKTQPVQGEPSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYLVRYRALSSEWKPEI
RLPSGSDHVMLKSLDWNAEYEVYVVAENQQGKSKAAHFVFRTSAQPTAIPANGSPTSGLS
TGAIVGILIVIFVLLLVVVDITCYFLNKCGLFMCIAVNLCGKAGPGAKGKDMEEGKAAFS
KDESKEPIVEVRTEEERTPNHDGGKHTEPNETTPLTEPEKGPVEAKPECQETETKPAPAE
VKTVPNDATQTKENESKA
NT seq 2577 nt   +upstreamnt  +downstreamnt
atgctgcaaactaaggatctcatctggactttgtttttcctgggaactgcagtttctctg
caggtggatattgttcccagccagggggagatcagcgttggagagtccaaattcttctta
tgccaagtggcaggagatgccaaagataaagacatctcctggttctcccccaatggagaa
aagctcaccccaaaccagcagcggatctcagtggtgtggaatgatgattcctcctccacc
ctcaccatctataacgccaacatcgacgacgccggcatttacaagtgtgtggttacaggc
gaggatggcagtgagtcagaggccaccgtcaacgtgaagatctttcagaagctcatgttc
aagaatgcgccaaccccacaggagttccgggagggggaagatgccgtgattgtgtgtgat
gtggtcagctccctcccaccaaccatcatctggaaacacaaaggccgagatgtcatcctg
aaaaaagatgtccgattcatagtcctgtccaacaactacctgcagatccggggcatcaag
aaaacagatgagggcacttatcgctgtgagggcagaatcctggcacggggggagatcaac
ttcaaggacattcaggtcattgtgaatgtgccacctaccatccaggccaggcagaatatt
gtgaatgccaccgccaacctcggccagtccgtcaccctggtgtgcgatgccgaaggcttc
ccagagcccaccatgagctggacaaaggatggggaacagatagagcaagaggaagacgat
gagaagtacatcttcagcgacgatagttcccagctgaccatcaaaaaggtggataagaac
gacgaggctgagtacatctgcattgctgagaacaaggctggcgagcaggatgcgaccatc
cacctcaaagtctttgcaaaacccaaaatcacatatgtagagaaccagactgccatggaa
ttagaggagcaggtcactcttacctgtgaagcctccggagaccccattccctccatcacc
tggaggacttctacccggaacatcagcagcgaagaaaaggcttcgtggactcgaccagag
aagcaagagactctggatgggcacatggtggtgcgtagccatgcccgtgtgtcgtcgctg
accctgaagagcatccagtacactgatgccggagagtacatctgcaccgccagcaacacc
atcggccaggactcccagtccatgtaccttgaagtgcaatatgccccaaagctacagggc
cctgtggctgtgtacacttgggaggggaaccaggtgaacatcacctgcgaggtatttgcc
tatcccagtgccacgatctcatggtttcgggatggccagctgctgccaagctccaattac
agcaatatcaagatctacaacaccccctctgccagctatctggaggtgaccccagactct
gagaatgattttgggaactacaactgtactgcagtgaaccgcattgggcaggagtccttg
gaattcatccttgttcaagcagacaccccctcttcaccatccatcgaccaggtggagcca
tactccagcacagcccaggtgcagtttgatgaaccagaggccacaggtggggtgcccatc
ctcaaatacaaagctgagtggagagcagttggtgaagaagtatggcattccaagtggtat
gatgccaaggaagccagcatggagggcatcgtcaccatcgtgggcctgaagcccgaaaca
acgtacgccgtaaggctggcggcgctcaatggcaaagggctgggtgagatcagcgcggcc
tccgagttcaagacgcagccagtccaaggggaacccagtgcacctaagctcgaagggcag
atgggagaggatggaaactctattaaagtgaacctgatcaagcaggatgacggcggctcc
cccatcagacactatctggtcaggtaccgagcgctctcctccgagtggaaaccagagatc
aggctcccgtctggcagtgaccacgtcatgctgaagtccctggactggaatgctgagtat
gaggtctacgtggtggctgagaaccagcaaggaaaatccaaggcggctcattttgtgttc
aggacctcggcccagcccacagccatcccagccaacggcagccccacctcaggcctgagc
accggggccatcgtgggcatcctcatcgtcatcttcgtcctgctcctggtggttgtggac
atcacctgctacttcctgaacaagtgtggcctgttcatgtgcattgcggtcaacctgtgt
ggaaaagccgggcccggggccaagggcaaggacatggaggagggcaaggccgccttctcg
aaagatgagtccaaggagcccatcgtggaggttcgaacggaggaggagaggaccccaaac
catgatggagggaaacacacagagcccaacgagaccacgccactgacggagcccgagaag
ggccccgtagaagcaaagccagagtgccaggagacagaaacgaagccagcgccagccgaa
gtcaagacggtccccaatgacgccacacagacaaaggagaacgagagcaaagcatga

  All links  
Ontology (6)   
   KEGG BRITE (6)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Drug (1)   
   KEGG DRUG (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (24)   
   KEGG ORTHOLOGY (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (8)   
   OC (1)   
Protein sequence (33)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (31)   
DNA sequence (87)   
   RefSeq(nuc) (31)   
   GenBank (28)   
   EMBL (28)   
3D Structure (7)   
   PDB (7)   
Protein domain (15)   
   Pfam (15)   
All databases (178)   

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