KEGG   Homo sapiens (human): 4690
Entry
4690              CDS       T01001                                 
Symbol
NCK1, NCK, NCKalpha, nck-1
Name
(RefSeq) NCK adaptor protein 1
  KO
K07365  NCK adaptor protein 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04012  ErbB signaling pathway
hsa04360  Axon guidance
hsa04660  T cell receptor signaling pathway
hsa05130  Pathogenic Escherichia coli infection
Network
nt06180  Pathogenic Escherichia coli
nt06182  Shigella
  Element
N01078  EGF-EGFR-Actin signaling pathway
N01092  Escherichia Eae/Tir to Actin signaling pathway
N01093  Escherichia EspJ/Tir to Actin signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    4690 (NCK1)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    4690 (NCK1)
  09158 Development and regeneration
   04360 Axon guidance
    4690 (NCK1)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    4690 (NCK1)
SSDB
Motif
Pfam: SH3_1 SH3_9 SH3_2 SH2 SH3_3 SH3_10 hSH3 SH2_2
Other DBs
NCBI-GeneID: 4690
NCBI-ProteinID: NP_001278928
OMIM: 600508
HGNC: 7664
Ensembl: ENSG00000158092
UniProt: P16333 A0A0S2Z4Y3
Structure
Position
3:136862208..136951606
AA seq 377 aa
MAEEVVVVAKFDYVAQQEQELDIKKNERLWLLDDSKSWWRVRNSMNKTGFVPSNYVERKN
SARKASIVKNLKDTLGIGKVKRKPSVPDSASPADDSFVDPGERLYDLNMPAYVKFNYMAE
REDELSLIKGTKVIVMEKCSDGWWRGSYNGQVGWFPSNYVTEEGDSPLGDHVGSLSEKLA
AVVNNLNTGQVLHVVQALYPFSSSNDEELNFEKGDVMDVIEKPENDPEWWKCRKINGMVG
LVPKNYVTVMQNNPLTSGLEPSPPQCDYIRPSLTGKFAGNPWYYGKVTRHQAEMALNERG
HEGDFLIRDSESSPNDFSVSLKAQGKNKHFKVQLKETVYCIGQRKFSTMEELVEHYKKAP
IFTSEQGEKLYLVKHLS
NT seq 1134 nt   +upstreamnt  +downstreamnt
atggcagaagaagtggtggtagtagccaaatttgattatgtggcccaacaagaacaagag
ttggacatcaagaagaatgagagattatggcttctggatgattctaagtcctggtggcga
gttcgaaattccatgaataaaacaggttttgtgccttctaactatgtggaaaggaaaaac
agtgctcggaaagcatctattgtgaaaaacctaaaggataccttaggcattggaaaagtg
aaaagaaaacctagtgtgccagattctgcatctcctgctgatgatagttttgttgaccca
ggggaacgtctctatgacctcaacatgcccgcttatgtgaaatttaactacatggctgag
agagaggatgaattatcattgataaaggggacaaaggtgatcgtcatggagaaatgcagt
gatgggtggtggcgtggtagctacaatggacaagttggatggttcccttcaaactatgta
actgaagaaggtgacagtcctttgggtgaccatgtgggttctctgtcagagaaattagca
gcagtcgtcaataacctaaatactgggcaagtgttgcatgtggtacaggctctttaccca
ttcagctcatctaatgatgaagaacttaatttcgagaaaggagatgtaatggatgttatt
gaaaaacctgaaaatgacccagagtggtggaaatgcaggaagatcaatggtatggttggt
ctagtaccaaaaaactatgttaccgttatgcagaataatccattaacttcaggtttggaa
ccatcacctccacagtgtgattacattaggccttcactcactggaaagtttgctggcaat
ccttggtattatggcaaagtcaccaggcatcaagcagaaatggcattaaatgaaagagga
catgaaggggatttcctcattcgtgatagtgaatcttcgccaaatgatttctcagtatca
ctaaaagcacaagggaaaaacaagcattttaaagtccaactaaaagagactgtctactgc
attgggcagcgtaaattcagcaccatggaagaacttgtagaacattacaaaaaggcacca
atttttacaagtgaacaaggagaaaaattatatcttgtcaagcatttatcatga

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Network (5)   
   KEGG NETWORK (5)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (14)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (11)   
DNA sequence (35)   
   RefSeq(nuc) (11)   
   GenBank (12)   
   EMBL (12)   
3D Structure (15)   
   PDB (15)   
Protein domain (8)   
   Pfam (8)   
All databases (95)   

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