KEGG   Homo sapiens (human): 4830
Entry
4830              CDS       T01001                                 
Symbol
NME1, AWD, GAAD, NB, NBS, NDKA, NDPK-A, NDPKA, NM23, NM23-H1
Name
(RefSeq) NME/NM23 nucleoside diphosphate kinase 1
  KO
K00940  nucleoside-diphosphate kinase [EC:2.7.4.6]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00230  Purine metabolism
hsa00240  Pyrimidine metabolism
hsa00983  Drug metabolism - other enzymes
hsa01100  Metabolic pathways
hsa01232  Nucleotide metabolism
hsa01240  Biosynthesis of cofactors
Module
hsa_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP
hsa_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP
hsa_M00052  Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP
hsa_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP
hsa_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    4830 (NME1)
   00240 Pyrimidine metabolism
    4830 (NME1)
  09111 Xenobiotics biodegradation and metabolism
   00983 Drug metabolism - other enzymes
    4830 (NME1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    4830 (NME1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.4  Phosphotransferases with a phosphate group as acceptor
    2.7.4.6  nucleoside-diphosphate kinase
     4830 (NME1)
Membrane trafficking [BR:hsa04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    4830 (NME1)
SSDB
Motif
Pfam: NDK
Other DBs
NCBI-GeneID: 4830
NCBI-ProteinID: NP_000260
OMIM: 156490
HGNC: 7849
Ensembl: ENSG00000239672
UniProt: P15531 A0A384MTW7
Structure
Position
17:51153559..51162168
AA seq 152 aa
MANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQASEDLLKEHYVDLKDRPF
FAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGS
DSVESAEKEIGLWFHPEELVDYTSCAQNWIYE
NT seq 459 nt   +upstreamnt  +downstreamnt
atggccaactgtgagcgtaccttcattgcgatcaaaccagatggggtccagcggggtctt
gtgggagagattatcaagcgttttgagcagaaaggattccgccttgttggtctgaaattc
atgcaagcttccgaagatcttctcaaggaacactacgttgacctgaaggaccgtccattc
tttgccggcctggtgaaatacatgcactcagggccggtagttgccatggtctgggagggg
ctgaatgtggtgaagacgggccgagtcatgctcggggagaccaaccctgcagactccaag
cctgggaccatccgtggagacttctgcatacaagttggcaggaacattatacatggcagt
gattctgtggagagtgcagagaaggagatcggcttgtggtttcaccctgaggaactggta
gattacacgagctgtgctcagaactggatctatgaatga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (11)   
   KEGG PATHWAY (6)   
   KEGG MODULE (5)   
Disease (1)   
   OMIM (1)   
Chemical substance (32)   
   KEGG COMPOUND (32)   
Chemical reaction (17)   
   KEGG ENZYME (1)   
   KEGG REACTION (16)   
Genome (1)   
   KEGG GENOME (1)   
Gene (52)   
   KEGG ORTHOLOGY (1)   
   RefGene (14)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (32)   
   OC (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (46)   
   RefSeq(nuc) (2)   
   GenBank (22)   
   EMBL (22)   
3D Structure (8)   
   PDB (8)   
Protein domain (1)   
   Pfam (1)   
All databases (177)   

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