KEGG   Homo sapiens (human): 4833
Entry
4833              CDS       T01001                                 
Symbol
NME4, NDPK-D, NM23H4, nm23-H4
Name
(RefSeq) NME/NM23 nucleoside diphosphate kinase 4
  KO
K00940  nucleoside-diphosphate kinase [EC:2.7.4.6]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00230  Purine metabolism
hsa00240  Pyrimidine metabolism
hsa00983  Drug metabolism - other enzymes
hsa01100  Metabolic pathways
hsa01232  Nucleotide metabolism
hsa01240  Biosynthesis of cofactors
Module
hsa_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP
hsa_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP
hsa_M00052  Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP
hsa_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP
hsa_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    4833 (NME4)
   00240 Pyrimidine metabolism
    4833 (NME4)
  09111 Xenobiotics biodegradation and metabolism
   00983 Drug metabolism - other enzymes
    4833 (NME4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    4833 (NME4)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.4  Phosphotransferases with a phosphate group as acceptor
    2.7.4.6  nucleoside-diphosphate kinase
     4833 (NME4)
Membrane trafficking [BR:hsa04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    4833 (NME4)
SSDB
Motif
Pfam: NDK PSI_PsaJ
Other DBs
NCBI-GeneID: 4833
NCBI-ProteinID: NP_005000
OMIM: 601818
HGNC: 7852
Ensembl: ENSG00000103202
UniProt: O00746
Structure
Position
16:396729..400754
AA seq 187 aa
MGGLFWRSALRGLRCGPRAPGPSLLVRHGSGGPSWTRERTLVAVKPDGVQRRLVGDVIQR
FERRGFTLVGMKMLQAPESVLAEHYQDLRRKPFYPALIRYMSSGPVVAMVWEGYNVVRAS
RAMIGHTDSAEAAPGTIRGDFSVHISRNVIHASDSVEGAQREIQLWFQSSELVSWADGGQ
HSSIHPA
NT seq 564 nt   +upstreamnt  +downstreamnt
atgggcggcctcttctggcgctccgcgctgcgggggctgcgctgcggcccgcgggccccg
ggcccgagcctgctagtgcgccacggctcgggagggccctcctggacccgggagcggacc
ctggtggcggtgaagcccgatggcgtgcaacggcggctcgttggggacgtgatccagcgc
tttgagaggcggggcttcacgctggtggggatgaagatgctgcaggcaccagagagcgtc
cttgccgagcactaccaggacctgcggaggaagcccttctaccctgccctcatccgctac
atgagctctgggcctgtggtggccatggtctgggaagggtacaatgtcgtccgcgcctcg
agggccatgattggacacaccgactcggctgaggctgccccaggaaccataaggggtgac
ttcagcgtccacatcagcaggaatgtcatccacgccagcgactccgtggagggggcccag
cgggagatccagctgtggttccagagcagtgagctggtgagctgggcagacgggggccag
cacagcagcatccacccagcctga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (11)   
   KEGG PATHWAY (6)   
   KEGG MODULE (5)   
Disease (1)   
   OMIM (1)   
Chemical substance (32)   
   KEGG COMPOUND (32)   
Chemical reaction (17)   
   KEGG ENZYME (1)   
   KEGG REACTION (16)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (9)   
   OC (1)   
Protein sequence (9)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (7)   
DNA sequence (35)   
   RefSeq(nuc) (7)   
   GenBank (14)   
   EMBL (14)   
3D Structure (1)   
   PDB (1)   
Protein domain (2)   
   Pfam (2)   
All databases (128)   

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