KEGG   Homo sapiens (human): 4838
Entry
4838              CDS       T01001                                 
Symbol
NODAL, HTX5
Name
(RefSeq) nodal growth differentiation factor
  KO
K04666  nodal
Organism
hsa  Homo sapiens (human)
Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04350  TGF-beta signaling pathway
hsa04550  Signaling pathways regulating pluripotency of stem cells
Network
nt06507  TGFB signaling
  Element
N01459  Nodal signaling pathway
Disease
H00632  Heterotaxy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    4838 (NODAL)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    4838 (NODAL)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    4838 (NODAL)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:hsa04052]
    4838 (NODAL)
Cytokines and neuropeptides [BR:hsa04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   4838 (NODAL)
SSDB
Motif
Pfam: TGF_beta TGFb_propeptide
Other DBs
NCBI-GeneID: 4838
NCBI-ProteinID: NP_060525
OMIM: 601265
HGNC: 7865
Ensembl: ENSG00000156574
UniProt: Q96S42
Structure
Position
10:complement(70431936..70447951)
AA seq 347 aa
MHAHCLPFLLHAWWALLQAGAATVATALLRTRGQPSSPSPLAYMLSLYRDPLPRADIIRS
LQAEDVAVDGQNWTFAFDFSFLSQQEDLAWAELRLQLSSPVDLPTEGSLAIEIFHQPKPD
TEQASDSCLERFQMDLFTVTLSQVTFSLGSMVLEVTRPLSKWLKHPGALEKQMSRVAGEC
WPRPPTPPATNVLLMLYSNLSQEQRQLGGSTLLWEAESSWRAQEGQLSWEWGKRHRRHHL
PDRSQLCRKVKFQVDFNLIGWGSWIIYPKQYNAYRCEGECPNPVGEEFHPTNHAYIQSLL
KRYQPHRVPSTCCAPVKTKPLSMLYVDNGRVLLDHHKDMIVEECGCL
NT seq 1044 nt   +upstreamnt  +downstreamnt
atgcacgcccactgcctgcccttccttctgcacgcctggtgggccctactccaggcgggt
gctgcgacggtggccactgcgctcctgcgtacgcgggggcagccctcgtcgccatcccct
ctggcgtacatgctgagcctctaccgcgacccgctgccgagggcagacatcatccgcagc
ctacaggcagaagatgtggcagtggatgggcagaactggacgtttgcttttgacttctcc
ttcctgagccaacaagaggatctggcatgggctgagctccggctgcagctgtccagccct
gtggacctccccactgagggctcacttgccattgagattttccaccagccaaagcccgac
acagagcaggcttcagacagctgcttagagcggtttcagatggacctattcactgtcact
ttgtcccaggtcaccttttccttgggcagcatggttttggaggtgaccaggcctctctcc
aagtggctgaagcaccctggggccctggagaagcagatgtccagggtagctggagagtgc
tggccgcggccccccacaccgcctgccaccaatgtgctccttatgctctactccaacctc
tcgcaggagcagaggcagctgggtgggtccaccttgctgtgggaagccgagagctcctgg
cgggcccaggagggacagctgtcctgggagtggggcaagaggcaccgtcgacatcacttg
ccagacagaagtcaactgtgtcggaaggtcaagttccaggtggacttcaacctgatcgga
tggggctcctggatcatctaccccaagcagtacaacgcctatcgctgtgagggcgagtgt
cctaatcctgttggggaggagtttcatccgaccaaccatgcatacatccagagtctgctg
aaacgttaccagccccaccgagtcccttccacttgttgtgccccagtgaagaccaagccg
ctgagcatgctgtatgtggataatggcagagtgctcctagatcaccataaagacatgatc
gtggaagaatgtgggtgcctctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Network (2)   
   KEGG NETWORK (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (14)   
   RefSeq(nuc) (4)   
   GenBank (5)   
   EMBL (5)   
3D Structure (1)   
   PDB (1)   
Protein domain (2)   
   Pfam (2)   
All databases (49)   

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