KEGG   Homo sapiens (human): 4839
Entry
4839              CDS       T01001                                 
Symbol
NOP2, NOL1, NOP120, NSUN1, p120
Name
(RefSeq) NOP2 nucleolar protein
  KO
K14835  25S rRNA (cytosine2870-C5)-methyltransferase [EC:2.1.1.310]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03009 Ribosome biogenesis [BR:hsa03009]
    4839 (NOP2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.310  25S rRNA (cytosine2870-C5)-methyltransferase
     4839 (NOP2)
Ribosome biogenesis [BR:hsa03009]
 Eukaryotic type
  Pre-60S particles
   Other pre-60S particles
    4839 (NOP2)
SSDB
Motif
Pfam: Methyltr_RsmB-F P120R Methyltr_RsmF_N PCMT Methyltransf_31 Methyltransf_25 FtsJ Prefoldin_2 Methyltransf_15 Met_10 Ubie_methyltran
Other DBs
NCBI-GeneID: 4839
NCBI-ProteinID: NP_001245237
OMIM: 164031
HGNC: 7867
Ensembl: ENSG00000111641
UniProt: P46087
Structure
Position
12:complement(6556871..6568291)
AA seq 812 aa
MGRKLDPTKEKRGPGRKARKQKGAETELVRFLPAVSDENSKRLSSRARKRAAKRRLGSVE
APKTNKSPEAKPLPGKLPKGISAGAVQTAGKKGPQSLFNAPRGKKRPAPGSDEEEEEEDS
EEDGMVNHGDLWGSEDDADTVDDYGADSNSEDEEEGEALLPIERAARKQKAREAAAGIQW
SEEETEDEEEEKEVTPESGPPKVEEADGGLQINVDEEPFVLPPAGEMEQDAQAPDLQRVH
KRIQDIVGILRDFGAQREEGRSRSEYLNRLKKDLAIYYSYGDFLLGKLMDLFPLSELVEF
LEANEVPRPVTLRTNTLKTRRRDLAQALINRGVNLDPLGKWSKTGLVVYDSSVPIGATPE
YLAGHYMLQGASSMLPVMALAPQEHERILDMCCAPGGKTSYMAQLMKNTGVILANDANAE
RLKSVVGNLHRLGVTNTIISHYDGRQFPKVVGGFDRVLLDAPCSGTGVISKDPAVKTNKD
EKDILRCAHLQKELLLSAIDSVNATSKTGGYLVYCTCSITVEENEWVVDYALKKRNVRLV
PTGLDFGQEGFTRFRERRFHPSLRSTRRFYPHTHNMDGFFIAKFKKFSNSIPQSQTGNSE
TATPTNVDLPQVIPKSENSSQPAKKAKGAAKTKQQLQKQQHPKKASFQKLNGISKGADSE
LSTVPSVTKTQASSSFQDSSQPAGKAEGIREPKVTGKLKQRSPKLQSSKKVAFLRQNAPP
KGTDTQTPAVLSPSKTQATLKPKDHHQPLGRAKGVEKQQLPEQPFEKAAFQKQNDTPKGP
QPPTVSPIRSSRPPPAKRKKSQSRGNSQLLLS
NT seq 2439 nt   +upstreamnt  +downstreamnt
atggggcgcaagttggaccctacgaaggagaagcgggggccaggccgaaaggcccggaag
cagaagggtgccgagacagaactcgtcagattcttgcctgcagtaagtgacgaaaattcc
aagaggctgtctagtcgtgctcgaaagagggcagccaagaggagattgggctctgttgaa
gcccctaagacaaataagtctcctgaggccaaaccattgcctggaaagctaccaaaaggg
atctctgcaggagctgtccagacagctggtaagaagggaccccagtccctatttaatgct
cctcgaggcaagaagcgcccagcacctggcagtgatgaggaagaggaggaggaagactct
gaagaagatggtatggtgaaccacggggacctctggggctccgaggacgatgctgatacg
gtagatgactatggagctgactccaactctgaggatgaggaggaaggtgaagcgttgctg
cccattgaaagagctgctcggaagcagaaggcccgggaagctgctgctgggatccagtgg
agtgaagaggagaccgaggacgaggaggaagagaaagaagtgacccctgagtcaggcccc
ccaaaggtggaagaggcagatgggggcctgcagatcaatgtggatgaggaaccatttgtg
ctgccccctgctggggagatggagcaggatgcccaggctccagacctgcaacgagttcac
aagcggatccaggatattgtgggaattctgcgtgattttggggctcagcgggaggaaggg
cggtctcgttctgaatacctgaaccggctcaagaaggatctggccatttactactcctat
ggagacttcctgcttggcaagctcatggacctcttccctctgtctgagctggtggagttc
ttagaagctaatgaggtgcctcggcccgtcaccctccggaccaataccttgaaaacccga
cgccgagaccttgcacaggctctaatcaatcgtggggttaacctggatcccctgggcaag
tggtcaaagactggactagtggtgtatgattcttctgtgcccattggtgctacccccgag
tacctggctgggcactacatgctgcagggagcctccagcatgttgcccgtcatggccttg
gcaccccaggaacatgagcggatcctggacatgtgttgtgcccctggaggaaagaccagc
tacatggcccagctgatgaagaacacgggtgtgatccttgccaatgacgccaatgctgag
cggctcaagagtgttgtgggcaacttgcatcggctgggagtcaccaacaccattatcagc
cactatgatgggcgccagttccccaaggtggtggggggctttgaccgagtactgctggat
gctccctgcagtggcactggggtcatctccaaggatccagccgtgaagactaacaaggat
gagaaggacatcctgcgctgtgctcacctccagaaggagttgctcctgagtgctattgac
tctgtcaatgcgacctccaagacaggaggctacctggtttactgcacctgttctatcaca
gtagaagagaatgagtgggtggtagactatgctctgaaaaagaggaatgtgcgactggtg
cccacgggcctagactttggccaggaaggttttacccgctttcgagaaaggcgcttccac
cccagtctgcgttctacccgacgcttctaccctcatacccacaatatggatgggttcttc
attgccaagttcaagaaattttccaattctatccctcagtcccagacaggaaattctgaa
acagccacacctacaaatgtagacttgcctcaggtcatccccaagtctgagaacagcagc
cagccagccaagaaagccaagggggctgcaaagacaaagcagcagctgcagaaacagcaa
catcccaagaaggcctccttccagaagctgaatggcatctccaaaggggcagactcagaa
ttgtccactgtaccttctgtcacaaagacccaagcttcctccagcttccaggatagcagt
cagccagctggaaaagccgaagggatcagggagccaaaggtgactgggaagctaaagcaa
cgatcacctaaattacagtcctccaagaaagttgctttcctcaggcagaatgcccctccc
aagggcacagacacacaaacaccggctgtgttatccccatccaagactcaggccaccctg
aaacctaaggaccatcatcagccccttggaagggccaagggggttgagaagcagcagttg
ccagagcagccttttgagaaagctgccttccagaaacagaatgatacccccaaggggcct
cagcctcccactgtgtctcccatccgttccagccgccccccaccagcaaagaggaagaaa
tctcagtccaggggcaacagccagctgctgctatcttag

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Ontology (3)   
   KEGG BRITE (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (12)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (33)   
   RefSeq(nuc) (5)   
   GenBank (14)   
   EMBL (14)   
3D Structure (6)   
   PDB (6)   
Protein domain (11)   
   Pfam (11)   
All databases (82)   

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