KEGG   Homo sapiens (human): 49
Entry
49                CDS       T01001                                 
Symbol
ACR, SPGF87
Name
(RefSeq) acrosin
  KO
K01317  acrosin [EC:3.4.21.10]
Organism
hsa  Homo sapiens (human)
Disease
H01282  Spermatogenic failure
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    49 (ACR)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    49 (ACR)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.10  acrosin
     49 (ACR)
Peptidases and inhibitors [BR:hsa01002]
 Serine peptidases
  Family S1: chymotrypsin family
   49 (ACR)
Membrane trafficking [BR:hsa04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Acrosomal exocytosis proteins
    49 (ACR)
SSDB
Motif
Pfam: Trypsin Trypsin_2
Other DBs
NCBI-GeneID: 49
NCBI-ProteinID: NP_001088
OMIM: 102480
HGNC: 126
Ensembl: ENSG00000100312
UniProt: P10323
Position
22:50738204..50745339
AA seq 421 aa
MVEMLPTAILLVLAVSVVAKDNATCDGPCGLRFRQNPQGGVRIVGGKAAQHGAWPWMVSL
QIFTYNSHRYHTCGGSLLNSRWVLTAAHCFVGKNNVHDWRLVFGAKEITYGNNKPVKAPL
QERYVEKIIIHEKYNSATEGNDIALVEITPPISCGRFIGPGCLPHFKAGLPRGSQSCWVA
GWGYIEEKAPRPSSILMEARVDLIDLDLCNSTQWYNGRVQPTNVCAGYPVGKIDTCQGDS
GGPLMCKDSKESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSNALRMIQSA
TPPPPTTRPPPIRPPFSHPISAHLPWYFQPPPRPLPPRPPAAQPRPPPSPPPPPPPPASP
LPPPPPPPPPTPSSTTKLPQGLSFAKRLQQLIEVLKGKTYSDGKNHYDMETTELPELTST
S
NT seq 1266 nt   +upstreamnt  +downstreamnt
atggttgagatgctaccaactgccattctgctggtcttggcagtgtccgtggttgctaaa
gataacgccacgtgtgatggcccctgtgggttacggttcaggcaaaacccacagggtggt
gtccgcatcgtcggcgggaaggctgcacagcatggggcctggccctggatggtcagcctc
cagatcttcacgtacaacagccacaggtaccacacatgtggaggcagcttgctgaattca
cgatgggtgctcactgctgctcactgcttcgtcggcaaaaataatgtgcatgactggaga
ctggttttcggagcaaaggaaattacatatgggaacaataaaccagtaaaggcgcctctg
caagagagatatgtggagaaaatcatcattcatgaaaaatacaactctgcgacagaggga
aatgacattgccctcgtggagatcacccctcccatttcgtgtgggcgcttcattgggccg
ggctgcctgccccactttaaggcaggcctccccagaggctcccagagctgctgggtggcc
ggctggggatatatagaagagaaagcccccaggccatcatctatactgatggaggcacgt
gtggatctcatcgacctggacttgtgtaactcgacccagtggtacaatgggcgcgttcag
ccaaccaatgtgtgcgcggggtatcctgtaggcaagatcgacacctgccagggagacagc
ggcgggcctctcatgtgcaaagacagcaaggaaagcgcctatgtggtcgtgggaatcaca
agctggggggtaggctgtgcccgtgccaagcgccccggaatctacacggccacctggccc
tatctgaactggatcgcctccaagattggttctaacgctttgcgtatgattcaatcggcc
acccctccacctcccaccactcgaccgcccccgattcgaccccccttctcccaccctatc
tctgctcaccttccttggtatttccaaccgccccctcgaccacttccaccccgaccaccg
gcagcccagccccgacccccaccttcacccccgcccccacccccacctccagcctcacct
ttacccccacccccacccccacccccacctacaccctcatctaccacaaaacttccccaa
ggactttcttttgccaagcgcctacagcagctcatagaggtcttgaaggggaagacctat
tccgacggaaagaaccattatgacatggagaccacagagctcccagaactgacctcgacc
tcctga

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Ontology (4)   
   KEGG BRITE (4)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (34)   
   KEGG ORTHOLOGY (1)   
   RefGene (28)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (9)   
   RefSeq(nuc) (1)   
   GenBank (4)   
   EMBL (4)   
Protein domain (2)   
   Pfam (2)   
All databases (57)   

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