KEGG   Homo sapiens (human): 4942
Entry
4942              CDS       T01001                                 
Symbol
OAT, GACR, HOGA, OATASE, OKT
Name
(RefSeq) ornithine aminotransferase
  KO
K00819  ornithine--oxo-acid transaminase [EC:2.6.1.13]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00330  Arginine and proline metabolism
hsa01100  Metabolic pathways
Module
hsa_M00972  Proline metabolism
Network
nt06033  Glycine, serine and arginine metabolism
  Element
N01618  Proline biosynthesis, Orn to Pro
Disease
H00189  Ornithinaemia
H01400  Secondary hyperammonemia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00330 Arginine and proline metabolism
    4942 (OAT)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01007 Amino acid related enzymes [BR:hsa01007]
    4942 (OAT)
Enzymes [BR:hsa01000]
 2. Transferases
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.13  ornithine aminotransferase
     4942 (OAT)
Amino acid related enzymes [BR:hsa01007]
 Aminotransferase (transaminase)
  Class III
   4942 (OAT)
SSDB
Motif
Pfam: Aminotran_3
Other DBs
NCBI-GeneID: 4942
NCBI-ProteinID: NP_000265
OMIM: 613349
HGNC: 8091
Ensembl: ENSG00000065154
UniProt: P04181 A0A140VJQ4
Structure
Position
10:complement(124397303..124418923)
AA seq 439 aa
MFSKLAHLQRFAVLSRGVHSSVASATSVATKKTVQGPPTSDDIFEREYKYGAHNYHPLPV
ALERGKGIYLWDVEGRKYFDFLSSYSAVNQGHCHPKIVNALKSQVDKLTLTSRAFYNNVL
GEYEEYITKLFNYHKVLPMNTGVEAGETACKLARKWGYTVKGIQKYKAKIVFAAGNFWGR
TLSAISSSTDPTSYDGFGPFMPGFDIIPYNDLPALERALQDPNVAAFMVEPIQGEAGVVV
PDPGYLMGVRELCTRHQVLFIADEIQTGLARTGRWLAVDYENVRPDIVLLGKALSGGLYP
VSAVLCDDDIMLTIKPGEHGSTYGGNPLGCRVAIAALEVLEEENLAENADKLGIILRNEL
MKLPSDVVTAVRGKGLLNAIVIKETKDWDAWKVCLRLRDNGLLAKPTHGDIIRFAPPLVI
KEDELRESIEIINKTILSF
NT seq 1320 nt   +upstreamnt  +downstreamnt
atgttttccaaactagcacatttgcagaggtttgctgtacttagtcgcggagttcattct
tcagtggcttctgctacatctgttgcaactaaaaaaacagtccaaggccctccaacctct
gatgacatttttgaaagggaatataagtatggtgcacacaactaccatcctttacctgta
gccctggagagaggaaaaggtatttacttatgggatgtagaaggcagaaaatattttgac
ttcctgagttcttacagtgctgtcaaccaagggcattgtcaccccaagattgtgaatgct
ctgaagagtcaagtggacaaattgaccttaacatctagagctttctataataacgtactt
ggtgaatatgaggagtatattactaaacttttcaactaccacaaagttcttcctatgaat
acaggagtggaggctggagagactgcctgtaaactagctcgtaagtggggctataccgtg
aagggcattcagaaatacaaagcaaagattgtttttgcagctgggaacttctggggtagg
acgttgtctgctatctccagttccacagacccaaccagttacgatggttttggaccattt
atgccgggattcgacatcattccctataatgatctgcccgcactggagcgtgctcttcag
gatccaaatgtggctgcgttcatggtagaaccaattcagggtgaagcaggcgttgttgtt
ccggatccaggttacctaatgggagtgcgagagctctgcaccaggcaccaggttctcttt
attgctgatgaaatacagacaggattggccagaactggtagatggctggctgttgattat
gaaaatgtcagacctgatatagtcctccttggaaaggccctttctgggggcttataccct
gtgtctgcagtgctgtgtgatgatgacatcatgctgaccattaagccaggggagcatggg
tccacatacggtggcaatccactaggctgccgagtggccatcgcagcccttgaggtttta
gaagaagaaaaccttgctgaaaatgcagacaaattgggcattatcttgagaaatgaactc
atgaagctaccttctgatgttgtaactgccgtaagaggaaaaggattattaaacgctatt
gtcattaaagaaaccaaagattgggatgcttggaaggtgtgtctacgacttcgagataat
ggacttctggccaagccaacccatggcgacattatcaggtttgcgcctccgctggtgatc
aaggaggatgagcttcgagagtccattgaaattattaacaagaccatcttgtctttctga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (2)   
   KEGG MODULE (1)   
Network (2)   
   KEGG NETWORK (2)   
Disease (4)   
   KEGG DISEASE (2)   
   OMIM (2)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (24)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (9)   
   OC (1)   
Protein sequence (13)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (10)   
DNA sequence (48)   
   RefSeq(nuc) (10)   
   GenBank (19)   
   EMBL (19)   
3D Structure (24)   
   PDB (24)   
Protein domain (1)   
   Pfam (1)   
All databases (129)   

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