KEGG   Homo sapiens (human): 494551
Entry
494551            CDS       T01001                                 
Symbol
WEE2, OOMD5, OZEMA5, WEE1B
Name
(RefSeq) WEE2 oocyte meiosis inhibiting kinase
  KO
K06632  wee1-like protein kinase [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04110  Cell cycle
hsa05170  Human immunodeficiency virus 1 infection
Disease
H01897  Oocyte/zygote/embryo maturation arrest
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    494551 (WEE2)
 09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    494551 (WEE2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    494551 (WEE2)
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:hsa03400]
    494551 (WEE2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     494551 (WEE2)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: Other
  WEE family
   494551 (WEE2)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  Check point factors
   Other check point factors
    494551 (WEE2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr
Other DBs
NCBI-GeneID: 494551
NCBI-ProteinID: NP_001099028
OMIM: 614084
HGNC: 19684
Ensembl: ENSG00000214102
UniProt: P0C1S8
Structure
Position
7:141708353..141731271
AA seq 567 aa
MDDKDIDKELRQKLNFSYCEETEIEGQKKVEESREASSQTPEKGEVQDSEAKGTPPWTPL
SNVHELDTSSEKDKESPDQILRTPVSHPLKCPETPAQPDSRSKLLPSDSPSTPKTMLSRL
VISPTGKLPSRGPKHLKLTPAPLKDEMTSLALVNINPFTPESYKKLFLQSGGKRKIRGDL
EEAGPEEGKGGLPAKRCVLRETNMASRYEKEFLEVEKIGVGEFGTVYKCIKRLDGCVYAI
KRSMKTFTELSNENSALHEVYAHAVLGHHPHVVRYYSSWAEDDHMIIQNEYCNGGSLQAA
ISENTKSGNHFEEPKLKDILLQISLGLNYIHNSSMVHLDIKPSNIFICHKMQSESSGVIE
EVENEADWFLSANVMYKIGDLGHATSINKPKVEEGDSRFLANEILQEDYRHLPKADIFAL
GLTIAVAAGAESLPTNGAAWHHIRKGNFPDVPQELSESFSSLLKNMIQPDAEQRPSAAAL
ARNTVLRPSLGKTEELQQQLNLEKFKTATLERELREAQQAQSPQGYTHHGDTGVSGTHTG
SRSTKRLVGGKSARSSSFTSGEREPLH
NT seq 1704 nt   +upstreamnt  +downstreamnt
atggatgacaaagatattgacaaagaactaaggcagaaattaaacttttcctattgtgag
gagactgagattgaagggcagaagaaagtagaagaaagcagggaggcttcgagccaaacc
ccagagaagggtgaagtgcaggattcagaggcaaagggtacaccaccttggactcccctt
agcaacgtgcatgagctcgacacatcttcggaaaaagacaaagaaagtccagatcagatt
ttgaggactccagtgtcacaccctctcaaatgtcctgagacaccagcccaaccagacagc
aggagcaagctgctgcccagtgacagcccctctactcccaaaaccatgctgagccggttg
gtgatttctccaacagggaagcttccttccagaggccctaagcatttgaagctcacacct
gctcccctcaaggatgagatgacctcattggctctggtcaatattaatcccttcactcca
gagtcctataaaaaattatttcttcaatctggtggcaagaggaaaataagaggagatctt
gaggaagctggtccagaggaaggcaagggagggctgcctgccaagagatgtgttttacga
gaaaccaacatggcttcccgctatgaaaaagaattcttggaggttgaaaaaattggggtt
ggcgaatttggtacagtctacaagtgcattaagaggctggatggatgtgtttatgcaata
aagcgctctatgaaaacttttacagaattatcaaatgagaattcggctttgcatgaagtt
tatgctcacgcagtgcttgggcatcacccccatgtggtacgttactattcctcatgggca
gaagatgaccacatgatcattcagaatgaatactgcaatggtgggagtttgcaagctgct
atatctgaaaacactaagtctggcaatcattttgaagagccaaaactcaaggacatcctt
ctacagatttcccttggccttaattacatccacaactctagcatggtacacctggacatc
aaacctagtaatatattcatttgtcacaagatgcaaagtgaatcctctggagtcatagaa
gaagttgaaaatgaagctgattggtttctctctgccaatgtgatgtataaaattggtgac
ctgggccacgcaacatcaataaacaaacccaaagtggaagaaggagatagtcgcttcctg
gctaatgagattttgcaagaggattaccggcaccttcccaaagcagacatatttgccttg
ggattaacaattgcagtggctgcaggagcagagtcattgcccaccaatggtgctgcatgg
caccatatccgcaagggtaactttccggacgttcctcaggagctctcagaaagcttttcc
agtctgctcaagaacatgatccaacctgatgccgaacagagaccttctgcagcagctctg
gccagaaatacagttctccggccttccctgggaaaaacagaagagctccaacagcagctg
aatttggaaaagttcaagactgccacactggaaagggaactgagagaagcccagcaggcc
cagtcaccccagggatatacccatcatggtgacactggggtctctgggacccacacagga
tcaagaagcacaaaacgcctggtgggaggaaagagtgcaaggtcttcaagctttacctca
ggagagcgtgagcctctgcattaa

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (7)   
   RefSeq(nuc) (1)   
   GenBank (3)   
   EMBL (3)   
3D Structure (1)   
   PDB (1)   
Protein domain (2)   
   Pfam (2)   
All databases (40)   

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