KEGG   Homo sapiens (human): 50
Entry
50                CDS       T01001                                 
Symbol
ACO2, ACONM, HEL-S-284, ICRD, OCA8, OPA9
Name
(RefSeq) aconitase 2
  KO
K01681  aconitate hydratase [EC:4.2.1.3]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00020  Citrate cycle (TCA cycle)
hsa00630  Glyoxylate and dicarboxylate metabolism
hsa01100  Metabolic pathways
hsa01200  Carbon metabolism
hsa01210  2-Oxocarboxylic acid metabolism
hsa01230  Biosynthesis of amino acids
Module
hsa_M00009  Citrate cycle (TCA cycle, Krebs cycle)
hsa_M00010  Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Network
nt06031  Citrate cycle and pyruvate metabolism
  Element
N01604  Citrate cycle, first carbon oxidation
Disease
H01020  Optic atrophy
H02113  Infantile cerebellar-retinal degeneration
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00020 Citrate cycle (TCA cycle)
    50 (ACO2)
   00630 Glyoxylate and dicarboxylate metabolism
    50 (ACO2)
Enzymes [BR:hsa01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.3  aconitate hydratase
     50 (ACO2)
SSDB
Motif
Pfam: Aconitase Aconitase_C
Other DBs
NCBI-GeneID: 50
NCBI-ProteinID: NP_001089
OMIM: 100850
HGNC: 118
Ensembl: ENSG00000100412
UniProt: Q99798
Position
22:41469117..41528974
AA seq 780 aa
MAPYSLLVTRLQKALGVRQYHVASVLCQRAKVAMSHFEPNEYIHYDLLEKNINIVRKRLN
RPLTLSEKIVYGHLDDPASQEIERGKSYLRLRPDRVAMQDATAQMAMLQFISSGLSKVAV
PSTIHCDHLIEAQVGGEKDLRRAKDINQEVYNFLATAGAKYGVGFWKPGSGIIHQIILEN
YAYPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVMAGIPWELKCPKVIGVKLTGSLSG
WSSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYN
HRMKKYLSKTGREDIANLADEFKDHLVPDPGCHYDQLIEINLSELKPHINGPFTPDLAHP
VAEVGKVAEKEGWPLDIRVGLIGSCTNSSYEDMGRSAAVAKQALAHGLKCKSQFTITPGS
EQIRATIERDGYAQILRDLGGIVLANACGPCIGQWDRKDIKKGEKNTIVTSYNRNFTGRN
DANPETHAFVTSPEIVTALAIAGTLKFNPETDYLTGTDGKKFRLEAPDADELPKGEFDPG
QDTYQHPPKDSSGQHVDVSPTSQRLQLLEPFDKWDGKDLEDLQILIKVKGKCTTDHISAA
GPWLKFRGHLDNISNNLLIGAINIENGKANSVRNAVTQEFGPVPDTARYYKKHGIRWVVI
GDENYGEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPADYNKIHP
VDKLTIQGLKDFTPGKPLKCIIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKELQQ
NT seq 2343 nt   +upstreamnt  +downstreamnt
atggcgccctacagcctactggtgactcggctgcagaaagctctgggtgtgcggcagtac
catgtggcctcagtcctgtgccaacgggccaaggtggcgatgagccactttgagcccaac
gagtacatccattatgacctgctagagaagaacattaacattgttcgcaaacgactgaac
cggccgctgacactctcggagaagattgtgtatggacacctggatgaccccgccagccag
gaaattgagcgaggcaagtcgtacctgcggctgcggccggaccgtgtggccatgcaggat
gcgacggcccagatggccatgctccagttcatcagcagcgggctgtccaaggtggctgtg
ccatccaccatccactgtgaccatctgattgaagcccaggttgggggcgagaaagacctg
cgccgggccaaggacatcaaccaggaagtttataatttcctggcaactgcaggtgccaaa
tatggcgtgggcttctggaagcctggatctggaatcattcaccagattattctggaaaac
tatgcgtaccctggtgttcttctgattggcactgactcccacacccccaatggtggcggc
cttgggggcatctgcattggagttgggggtgccgatgctgtggatgtcatggctgggatc
ccctgggagctgaagtgccccaaggtgattggcgtgaagctgacgggctctctctccggt
tggtcctcacccaaagatgtgatcctgaaggtggcaggcatcctcacggtgaaaggtggc
acaggtgcaatcgtggaataccacgggcctggtgtagactccatctcctgcactggcatg
gcgacaatctgcaacatgggtgcagaaattggggccaccacttccgtgttcccttacaac
cacaggatgaagaagtacctgagcaagaccggccgggaagacattgccaatctagctgat
gaattcaaggatcacttggtgcctgaccctggctgccattatgaccaactaattgaaatt
aacctcagtgagctgaagccacacatcaatgggcccttcacccctgacctggctcaccct
gtggcagaagtgggcaaggtggcagagaaggaaggatggcctctggacatccgagtgggt
ctaattggtagctgcaccaattcaagctatgaagatatggggcgctcagcagctgtggcc
aagcaggcactggcccatggcctcaagtgcaagtcccagttcaccatcactccaggttcc
gagcagatccgcgccaccattgagcgggacggctatgcacagatcttgagggatctgggt
ggcattgtcctggccaatgcttgtggcccctgcattggccagtgggacaggaaggacatc
aagaagggggagaagaacacaatcgtcacctcctacaacaggaacttcacgggccgcaac
gacgcaaaccccgagacccatgcctttgtcacgtccccagagattgtcacagccctggcc
attgcgggaaccctcaagttcaacccagagaccgactacctgacgggcacggatggcaag
aagttcaggctggaggctccggatgcagatgagcttcccaaaggggagtttgacccaggg
caggacacctaccagcacccacccaaggacagcagcgggcagcatgtggacgtgagcccc
accagccagcgcctgcagctcctggagccttttgacaagtgggatggcaaggacctggag
gacctgcagatcctcatcaaggtcaaagggaagtgtaccactgaccacatctcagctgct
ggcccctggctcaagttccgtgggcacttggataacatctccaacaacctgctcattggt
gccatcaacattgaaaacggcaaggccaactccgtgcgcaatgccgtcactcaggagttt
ggccccgtccctgacactgcccgctactacaagaaacatggcatcaggtgggtggtgatc
ggagacgagaactacggcgagggctcgagccgggagcatgcagctctggagcctcgccac
cttgggggccgggccatcatcaccaagagctttgccaggatccacgagaccaacctgaag
aaacagggcctgctgcctctgaccttcgctgacccggctgactacaacaagattcaccct
gtggacaagctgaccattcagggcctgaaggacttcacccctggcaagcccctgaagtgc
atcatcaagcaccccaacgggacccaggagaccatcctcctgaaccacaccttcaacgag
acgcagattgagtggttccgcgctggcagtgccctcaacagaatgaaggaactgcaacag
tga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (11)   
   KEGG PATHWAY (6)   
   KEGG MODULE (5)   
Network (2)   
   KEGG NETWORK (2)   
Disease (5)   
   KEGG DISEASE (2)   
   OMIM (3)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (30)   
   RefSeq(nuc) (2)   
   GenBank (14)   
   EMBL (14)   
Protein domain (2)   
   Pfam (2)   
All databases (80)   

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