KEGG   Homo sapiens (human): 51060
Entry
51060             CDS       T01001                                 
Symbol
TXNDC12, AG1, AGR1, ERP16, ERP18, ERP19, PDIA16, TLP19, hAG-1, hTLP19
Name
(RefSeq) thioredoxin domain containing 12
  KO
K05360  protein-disulfide reductase (glutathione) [EC:1.8.4.2]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00480  Glutathione metabolism
hsa01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    51060 (TXNDC12)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    51060 (TXNDC12)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.8  Acting on a sulfur group of donors
   1.8.4  With a disulfide as acceptor
    1.8.4.2  protein-disulfide reductase (glutathione)
     51060 (TXNDC12)
Membrane trafficking [BR:hsa04131]
 Endoplasmic reticulum (ER) - Golgi transport
  Forward pathways
   PDI family proteins
    51060 (TXNDC12)
SSDB
Motif
Pfam: Thioredoxin_7 Thioredoxin Thioredoxin_2 Thioredox_DsbH Thioredoxin_8 AhpC-TSA Thioredoxin_9
Other DBs
NCBI-GeneID: 51060
NCBI-ProteinID: NP_056997
OMIM: 609448
HGNC: 24626
Ensembl: ENSG00000117862
UniProt: O95881
Structure
Position
1:complement(52020131..52056171)
AA seq 172 aa
METRPRLGATCLLGFSFLLLVISSDGHNGLGKGFGDHIHWRTLEDGKKEAAASGLPLMVI
IHKSWCGACKALKPKFAESTEISELSHNFVMVNLEDEEEPKDEDFSPDGGYIPRILFLDP
SGKVHPEIINENGNPSYKYFYVSAEQVVQGMKEAQERLTGDAFRKKHLEDEL
NT seq 519 nt   +upstreamnt  +downstreamnt
atggagacgcggcctcgtctcggggccacctgtttgctgggcttcagtttcctgctcctc
gtcatctcttctgatggacataatgggcttggaaagggttttggagatcatattcattgg
aggacactggaagatgggaagaaagaagcagctgccagtggactgcccctgatggtgatt
attcataaatcctggtgtggagcttgcaaagctctaaagcccaaatttgcagaatctacg
gaaatttcagaactctcccataattttgttatggtaaatcttgaggatgaagaggaaccc
aaagatgaagatttcagccctgacgggggttatattccacgaatcctttttctggatccc
agtggcaaggtgcatcctgaaatcatcaatgagaatggaaaccccagctacaagtatttt
tatgtcagtgccgagcaagttgttcaggggatgaaggaagctcaggaaaggctgacgggt
gatgccttcagaaagaaacatcttgaagatgaattgtaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (23)   
   RefSeq(nuc) (3)   
   GenBank (10)   
   EMBL (10)   
3D Structure (2)   
   PDB (2)   
Protein domain (7)   
   Pfam (7)   
All databases (67)   

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