KEGG   Homo sapiens (human): 51585
Entry
51585             CDS       T01001                                 
Symbol
PCF11
Name
(RefSeq) PCF11 cleavage and polyadenylation factor subunit
  KO
K14400  pre-mRNA cleavage complex 2 protein Pcf11
Organism
hsa  Homo sapiens (human)
Pathway
hsa03015  mRNA surveillance pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    51585 (PCF11)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:hsa03021]
    51585 (PCF11)
   03019 Messenger RNA biogenesis [BR:hsa03019]
    51585 (PCF11)
Transcription machinery [BR:hsa03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     51585 (PCF11)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA processing factors
   3' end processing
    Pre-mRNA cleavage factor IIm (CFIIm)
     51585 (PCF11)
SSDB
Motif
Pfam: PCF11_RFEG_rpt PCF11_charged Pcf11_helical CID CFIA_Pcf11
Other DBs
NCBI-GeneID: 51585
NCBI-ProteinID: NP_056969
OMIM: 608876
HGNC: 30097
Ensembl: ENSG00000165494
UniProt: O94913
Structure
Position
11:83157131..83187451
AA seq 1555 aa
MSEQTPAEAGAAGAREDACRDYQSSLEDLTFNSKPHINMLTILAEENLPFAKEIVSLIEA
QTAKAPSSEKLPVMYLMDSIVKNVGREYLTAFTKNLVATFICVFEKVDENTRKSLFKLRS
TWDEIFPLKKLYALDVRVNSLDPAWPIKPLPPNVNTSSIHVNPKFLNKSPEEPSTPGTVV
SSPSISTPPIVPDIQKNLTQEQLIRQQLLAKQKQLLELQQKKLELELEQAKAQLAVSLSV
QQETSNLGPGSAPSKLHVSQIPPMAVKAPHQVPVQSEKSRPGPSLQIQDLKGTNRDPRLN
RISQHSHGKDQSHRKEFLMNTLNQSDTKTSKTIPSEKLNSSKQEKSKSGEKITKKELDQL
DSKSKSKSKSPSPLKNKLSHTKDLKNQESESMRLSDMNKRDPRLKKHLQDKTDGKDDDVK
EKRKTAEKKDKDEHMKSSEHRLAGSRNKIINGIVQKQDTITEESEKQGTKPGRSSTRKRS
RSRSPKSRSPIIHSPKRRDRRSPKRRQRSMSPTSTPKAGKIRQSGAKQSHMEEFTPPSRE
DRNAKRSTKQDIRDPRRMKKTEEERPQETTNQHSTKSGTEPKENVENWQSSKSAKRWKSG
WEENKSLQQVDEHSKPPHLRHRESWSSTKGILSPRAPKQQQHRLSVDANLQIPKELTLAS
KRELLQKTSERLASGEITQDDFLVVVHQIRQLFQYQEGVREEQRSPFNDRFPLKRPRYED
SDKPFVDSPASRFAGLDTNQRLTALAEDRPLFDGPSRPSVARDGPTKMIFEGPNKLSPRI
DGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQ
AGGGGFRFEGSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGPHGQPVG
GLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEGPLLQQGVGMRFEGPH
GQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEGPSVPGGGLRI
EGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFERTPGQPGPQRFDGPPG
QQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTRFDNHPSQRLESVSFNQTGPYNDPPG
NAFNAPSQGLQFQRHEQIFDSPQGPNFNGPHGPGNQSFSNPLNRASGHYFDEKNLQSSQF
GNFGNIPAPMTVGNIQASQQVLSGVAQPVAFGQGQQFLPVHPQNPGFVQNPSGALPKAYP
DNHLSQVDVNELFSKLLKTGILKLSQTDSATTQVSEVTAQPPPEEEEDQNEDQDVPDLTN
FTVEELKQRYDSVINRLYTGIQCYSCGMRFTTSQTDVYADHLDWHYRQNRTEKDVSRKVT
HRRWYYSLTDWIEFEEIADLEERAKSQFFEKVHEEVVLKTQEAAKEKEFQSVPAGPAGAV
ESCEICQEQFEQYWDEEEEEWHLKNAIRVDGKIYHPSCYEDYQNTSSFDCTPSPSKTPVE
NPLNIMLNIVKNELQEPCDSPKVKEERIDTPPACTEESIATPSEIKTENDTVESV
NT seq 4668 nt   +upstreamnt  +downstreamnt
atgtcagagcagacgccggccgaggccggtgctgcgggggcccgggaggacgcctgtcgg
gattatcagtcatcgctcgaagacctgaccttcaatagcaagccgcacatcaatatgctg
accattctagccgaggagaacctgcccttcgccaaggagatcgtctctctcatcgaggcc
caaaccgccaaggctccttcctcagagaagcttcctgttatgtaccttatggattctatt
gtgaaaaacgttggaagagagtatctcactgcctttactaaaaatctagttgcaacattt
atttgtgtgtttgaaaaggtggatgaaaatactaggaaaagtttatttaagttacgttct
acatgggatgaaatattccctttgaagaaactttatgccctggatgtcagagtcaattca
ttagatcctgcttggcctattaaacctctaccccccaatgtgaatacgtctagcatccat
gtgaatcctaaatttttaaataaatcgcccgaggagccttcaacacctggtacagtggtc
agttcccctagcatctccactcctccaattgttcctgatatacaaaagaatcttacacaa
gaacaactaataaggcagcagttactggcaaagcaaaaacagttgttagaacttcagcag
aaaaagctggagcttgagctagagcaagctaaggcacagttggcagtttctcttagtgtt
cagcaggaaacatccaatttaggtcctggatctgcaccatccaaattacatgtttcacag
attccccctatggcagttaaagctcctcatcaggttcctgtgcaatctgagaaaagccgt
ccaggaccatccttacaaattcaggatttaaaaggaactaaccgggatcctcgtctgaac
aggataagccaacattctcatggaaaagatcagagtcacaggaaagaatttctaatgaac
acattaaaccagtctgatactaagacaagtaaaactataccctctgaaaaactaaattca
tccaagcaagaaaaaagtaaatcaggtgaaaaaataaccaagaaagaacttgaccaatta
gattctaaatcgaaatcgaaatcgaaatcaccctcacctttgaaaaacaaattatctcac
acaaaagacttgaaaaatcaagaatcggaaagtatgaggttgtctgatatgaacaagaga
gatccaagattaaaaaaacatcttcaggataagaccgatggcaaagatgatgatgtgaaa
gagaagagaaaaactgcagaaaaaaaggataaagatgagcacatgaagtcatccgaacac
agactggctggaagtagaaataaaatcataaatggcattgtacaaaaacaggatacaata
acagaagagtcagaaaaacaggggacaaaaccagggagatcgagtactagaaagcgatca
agatctcgatcacccaagtctaggtcaccaattatacattccccaaagagaagagatagg
cggtcacccaaacgaaggcaaagaagtatgtctccaacatcgacacctaaagctggaaag
attcgccaatctggagctaagcagtcacatatggaagagtttacaccaccttctagggaa
gacagaaatgctaagagaagtactaaacaggatattcgggatccaaggcgaatgaaaaag
actgaagaggagcgaccacaagaaactacaaatcagcattctacaaagtcaggcactgaa
ccaaaggagaatgtagaaaactggcaaagttccaagtctgccaaaagatggaaatctggt
tgggaagaaaataaaagcttacaacaggttgatgaacatagtaaacctcctcatctgagg
catagggagagctggtcaagcactaaaggaattttatcacctcgagccccaaagcagcaa
cagcatcgattaagtgtagatgccaatcttcagattcctaaagagttaactcttgcaagc
aaaagagaattacttcaaaagacgagtgaacgtttagcatctggtgaaattacacaggat
gacttccttgttgttgtgcatcaaattcgacagctatttcagtatcaagaaggtgtgcga
gaagagcagagatctccattcaatgatcgttttccacttaagcgacctcgatatgaagat
tcagataaaccatttgtagatagtccagcatcaagattcgccggcctggatacaaatcag
cgacttacagctttagctgaagacagaccgttatttgatggacctagtaggccatcagta
gcaagagatggcccaacgaagatgatttttgaaggacccaataaattaagccctcgaatt
gatggacctcccacaccagcttctcttcggtttgatgggtcaccaggacaaatgggggga
ggaggccctttgagatttgaggggccacaaggtcagctaggaggtgggtgtcctttgaga
tttgaaggtcctccaggaccagtggggacacctctgcggtttgagggcccaattggtcaa
gcaggaggaggtggttttcggtttgaaggttcccctggtctgaggtttgagggatctcca
ggtggtttgagatttgagggaccaggaggccagcctgtgggtggtctgaggtttgaggga
catcgtggtcaacctgtgggtggtctaaggtttgagggacctcatggtcagcctgtgggt
ggacttagatttgataatccccgaggtcagcctgtaggtggacttagatttgaggggggt
catggtccatcaggggctgcgattaggtttgatggacctcatggtcagccaggaggtgga
atcagatttgagggccctttgctacagcaaggggttggaatgaggtttgagggcccccat
ggtcagtcagtagctggtctgagatttgagggacaacataatcaacttggtgggaacctt
aggtttgagggtccacatggtcagccaggggttggtatcaggtttgaaggccctttagtc
caacaaggaggtggaatgaggtttgagggtccttctgtaccaggaggtggcctgagaatt
gaagggcctctgggtcaaggtggtccaagatttgaaggttgtcatgctttaaggtttgat
gggcagccaggtcagccgtcactcttgccaagatttgatggattacatggtcagccaggt
cctagatttgaaaggactcctggtcagccaggccctcagaggtttgatggaccacctgga
cagcaggttcaacccagatttgacggtgtacctcaaagatttgatggtccacaacatcag
caagcatcaaggtttgatattcctcttggtcttcaaggcacaagatttgacaatcatcct
tcacaaaggcttgaatcagtatctttcaatcagactggtccatataatgatccacctggc
aatgcttttaatgccccatcccaaggactacagttccaaagacatgaacaaatatttgat
tcacctcaaggaccaaattttaatggaccacatggccctggaaaccagagtttctctaat
ccacttaacagagcttctggacactattttgatgaaaaaaatcttcagagttctcaattt
ggaaactttggcaatatacctgctccaatgacagtaggaaatattcaggcatctcaacag
gttctgagtggtgttgctcagccagtagcttttggtcaaggacaacagtttttaccagtt
catccacaaaatcctggatttgttcagaatccttcaggagccctccctaaggcatatcct
gataatcatctcagtcaggtggatgtaaatgaattgttttcaaaattgctaaaaacagga
attctcaaattgtcccaaactgattcagctacaacacaagtaagtgaagtaactgctcag
cctccccctgaagaggaggaagatcaaaatgaagatcaagatgttccagatcttactaat
tttacagttgaagaattgaaacaacgttatgacagtgttataaatcgactgtacactggt
attcagtgttactcttgtggaatgaggtttacaacatcacagacagatgtttatgcagat
catttggactggcattatcggcaaaatagaactgaaaaggatgttagccgaaaagtcact
catagacgttggtactacagtttaacagactggatagaatttgaggagatagctgatctg
gaagaacgggcaaagagccagttttttgaaaaggtgcatgaagaagttgtgctcaaaact
caagaggctgctaaagaaaaagagttccaaagtgtacctgctggaccagctggagcagtt
gagagttgtgaaatctgtcaagaacaatttgaacaatactgggatgaagaagaggaggaa
tggcatttgaaaaatgctattagagtagatggaaagatttatcatccatcatgttatgaa
gattatcaaaatacatcttcatttgattgtacaccatctcccagcaagacaccagttgaa
aaccccttgaatattatgttgaacattgtcaaaaacgaattgcaggaaccctgtgacagt
cccaaagttaaggaagaacgaattgatacaccaccagcttgtacagaggaaagcatagca
acaccctctgaaattaaaacagaaaatgacacagtcgagtcagtttaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (26)   
   KEGG ORTHOLOGY (1)   
   RefGene (19)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (8)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (24)   
   RefSeq(nuc) (6)   
   GenBank (9)   
   EMBL (9)   
3D Structure (1)   
   PDB (1)   
Protein domain (5)   
   Pfam (5)   
All databases (70)   

Download RDF
DBGET integrated database retrieval system