KEGG   Homo sapiens (human): 51588
Entry
51588             CDS       T01001                                 
Symbol
PIAS4, PIAS-gamma, PIASY, Piasg, ZMIZ6
Name
(RefSeq) protein inhibitor of activated STAT 4
  KO
K16065  E3 SUMO-protein ligase PIAS4 [EC:2.3.2.27]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04064  NF-kappa B signaling pathway
hsa04120  Ubiquitin mediated proteolysis
hsa04630  JAK-STAT signaling pathway
hsa05418  Fluid shear stress and atherosclerosis
Network
nt06506  Double-strand break repair
  Element
N01439  Double-strand break signaling
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    51588 (PIAS4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    51588 (PIAS4)
   04064 NF-kappa B signaling pathway
    51588 (PIAS4)
 09160 Human Diseases
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    51588 (PIAS4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    51588 (PIAS4)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     51588 (PIAS4)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  UBL E3 ligases
   51588 (PIAS4)
SSDB
Motif
Pfam: PINIT zf-MIZ zf-Nse DARPP-32 SAP
Other DBs
NCBI-GeneID: 51588
NCBI-ProteinID: NP_056981
OMIM: 605989
HGNC: 17002
Ensembl: ENSG00000105229
UniProt: Q8N2W9 B3KMR4
Position
19:4007736..4039386
AA seq 510 aa
MAAELVEAKNMVMSFRVSDLQMLLGFVGRSKSGLKHELVTRALQLVQFDCSPELFKKIKE
LYETRYAKKNSEPAPQPHRPLDPLTMHSTYDRAGAVPRTPLAGPNIDYPVLYGKYLNGLG
RLPAKTLKPEVRLVKLPFFNMLDELLKPTELVPQNNEKLQESPCIFALTPRQVELIRNSR
ELQPGVKAVQVVLRICYSDTSCPQEDQYPPNIAVKVNHSYCSVPGYYPSNKPGVEPKRPC
RPINLTHLMYLSSATNRITVTWGNYGKSYSVALYLVRQLTSSELLQRLKTIGVKHPELCK
ALVKEKLRLDPDSEIATTGVRVSLICPLVKMRLSVPCRAETCAHLQCFDAVFYLQMNEKK
PTWMCPVCDKPAPYDQLIIDGLLSKILSECEDADEIEYLVDGSWCPIRAEKERSCSPQGA
ILVLGPSDANGLLPAPSVNGSGALGSTGGGGPVGSMENGKPGADVVDLTLDSSSSSEDEE
EEEEEEEDEDEEGPRPKRRCPFQKGLVPAC
NT seq 1533 nt   +upstreamnt  +downstreamnt
atggcggcggagctggtggaggccaaaaacatggtgatgagttttcgagtctccgacctt
cagatgctcctgggtttcgtgggccggagtaagagtggactgaagcacgagctcgtcacc
agggccctccagctggtgcagtttgactgtagccctgagctgttcaagaagatcaaggag
ctgtacgagacccgctacgccaagaagaactcggagcctgccccacagccgcaccggccc
ctggaccccctgaccatgcactccacctacgaccgggccggcgctgtgcccaggactccg
ctggcaggccccaatattgactaccccgtgctctacggaaagtacttaaacggactggga
cggttgcccgccaagaccctcaagccagaagtccgcctggtgaagctgccgttctttaat
atgctggatgagctgctgaagcccaccgaattagtcccacagaacaacgagaagcttcag
gagagcccgtgcatcttcgcattgacgccaagacaggtggagttgatccggaactccagg
gaactgcagcccggagttaaagccgtgcaggtcgtcctgagaatctgttactcagacacc
agctgccctcaggaggaccagtacccgcccaacatcgctgtgaaggtcaaccacagctac
tgctccgtcccgggctactacccctccaataagcccggggtggagcccaagaggccgtgc
cgccccatcaacctcacccacctcatgtacctgtcctcggccaccaaccgcatcactgtc
acctgggggaactacggcaagagctactcggtggccctgtacctggtgcggcagctgacc
tcatcggagctgctgcagaggctgaagaccattggggtaaagcacccggagctgtgcaag
gcactggtcaaggagaagctgcgccttgatcctgacagcgagatcgccaccaccggtgtg
cgggtgtccctcatctgtccgctggtgaagatgcggctctccgtgccctgccgggcagag
acctgtgcccacctgcagtgcttcgacgccgtcttctacctgcagatgaacgagaagaag
cccacctggatgtgccccgtgtgcgacaagccagccccctacgaccagctcatcatcgac
gggctcctctcgaagatcctgagcgagtgtgaggacgccgacgagatcgagtacctggtg
gacggctcgtggtgcccgatccgcgccgaaaaggagcgcagctgcagcccgcagggcgcc
atcctcgtgctgggcccctcggacgccaatgggctcctgcccgcccccagcgtcaacggg
agcggtgccctgggcagcacgggtggcggcggcccggtgggcagcatggagaatgggaag
ccgggcgccgatgtggtggacctcacgctggacagctcatcgtcctcggaggatgaggag
gaggaggaagaggaggaggaagacgaggacgaagaggggccccggcccaagcgccgctgc
cccttccagaagggcctggtgccggcctgctga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (4)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
Protein sequence (8)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (28)   
   RefSeq(nuc) (6)   
   GenBank (11)   
   EMBL (11)   
Protein domain (5)   
   Pfam (5)   
All databases (70)   

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