KEGG   Homo sapiens (human): 5169
Entry
5169              CDS       T01001                                 
Symbol
ENPP3, B10, CD203c, NPP3, PD-IBETA, PDNP3
Name
(RefSeq) ectonucleotide pyrophosphatase/phosphodiesterase 3
  KO
K01513  ectonucleotide pyrophosphatase/phosphodiesterase family member 1/3 [EC:3.1.4.1 3.6.1.9]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00230  Purine metabolism
hsa00240  Pyrimidine metabolism
hsa00500  Starch and sucrose metabolism
hsa00740  Riboflavin metabolism
hsa00760  Nicotinate and nicotinamide metabolism
hsa00770  Pantothenate and CoA biosynthesis
hsa01100  Metabolic pathways
hsa01232  Nucleotide metabolism
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00500 Starch and sucrose metabolism
    5169 (ENPP3)
  09104 Nucleotide metabolism
   00230 Purine metabolism
    5169 (ENPP3)
   00240 Pyrimidine metabolism
    5169 (ENPP3)
  09108 Metabolism of cofactors and vitamins
   00740 Riboflavin metabolism
    5169 (ENPP3)
   00760 Nicotinate and nicotinamide metabolism
    5169 (ENPP3)
   00770 Pantothenate and CoA biosynthesis
    5169 (ENPP3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:hsa04090]
    5169 (ENPP3)
   00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:hsa00537]
    5169 (ENPP3)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.1  phosphodiesterase I
     5169 (ENPP3)
  3.6  Acting on acid anhydrides
   3.6.1  In phosphorus-containing anhydrides
    3.6.1.9  nucleotide diphosphatase
     5169 (ENPP3)
CD molecules [BR:hsa04090]
 Proteins
  5169 (ENPP3)
Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:hsa00537]
 Enzymes
  5169 (ENPP3)
SSDB
Motif
Pfam: Phosphodiest Somatomedin_B Endonuclease_NS Metalloenzyme Sulfatase Arginosuc_syn_C
Other DBs
NCBI-GeneID: 5169
NCBI-ProteinID: NP_005012
OMIM: 602182
HGNC: 3358
Ensembl: ENSG00000154269
UniProt: O14638
Structure
Position
6:131637302..131747410
AA seq 875 aa
MESTLTLATEQPVKKNTLKKYKIACIVLLALLVIMSLGLGLGLGLRKLEKQGSCRKKCFD
ASFRGLENCRCDVACKDRGDCCWDFEDTCVESTRIWMCNKFRCGETRLEASLCSCSDDCL
QRKDCCADYKSVCQGETSWLEENCDTAQQSQCPEGFDLPPVILFSMDGFRAEYLYTWDTL
MPNINKLKTCGIHSKYMRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVNLNKNFSLS
SKEQNNPAWWHGQPMWLTAMYQGLKAATYFWPGSEVAINGSFPSIYMPYNGSVPFEERIS
TLLKWLDLPKAERPRFYTMYFEEPDSSGHAGGPVSARVIKALQVVDHAFGMLMEGLKQRN
LHNCVNIILLADHGMDQTYCNKMEYMTDYFPRINFFYMYEGPAPRIRAHNIPHDFFSFNS
EEIVRNLSCRKPDQHFKPYLTPDLPKRLHYAKNVRIDKVHLFVDQQWLAVRSKSNTNCGG
GNHGYNNEFRSMEAIFLAHGPSFKEKTEVEPFENIEVYNLMCDLLRIQPAPNNGTHGSLN
HLLKVPFYEPSHAEEVSKFSVCGFANPLPTESLDCFCPHLQNSTQLEQVNQMLNLTQEEI
TATVKVNLPFGRPRVLQKNVDHCLLYHREYVSGFGKAMRMPMWSSYTVPQLGDTSPLPPT
VPDCLRADVRVPPSESQKCSFYLADKNITHGFLYPPASNRTSDSQYDALITSNLVPMYEE
FRKMWDYFHSVLLIKHATERNGVNVVSGPIFDYNYDGHFDAPDEITKHLANTDVPIPTHY
FVVLTSCKNKSHTPENCPGWLDVLPFIIPHRPTNVESCPEGKPEALWVEERFTAHIARVR
DVELLTGLDFYQDKVQPVSEILQLKTYLPTFETTI
NT seq 2628 nt   +upstreamnt  +downstreamnt
atggaatctacgttgactttagcaacggaacaacctgttaagaagaacactcttaagaaa
tataaaatagcttgcattgttcttcttgctttgctggtgatcatgtcacttggattaggc
ctggggcttggactcaggaaactggaaaagcaaggcagctgcaggaagaagtgctttgat
gcatcatttagaggactggagaactgccggtgtgatgtggcatgtaaagaccgaggtgat
tgctgctgggattttgaagacacctgtgtggaatcaactcgaatatggatgtgcaataaa
tttcgttgtggagagaccagattagaggccagcctttgctcttgttcagatgactgtttg
cagaggaaagattgctgtgctgactataagagtgtttgccaaggagaaacctcatggctg
gaagaaaactgtgacacagcccagcagtctcagtgcccagaagggtttgacctgccacca
gttatcttgttttctatggatggatttagagctgaatatttatacacatgggatacttta
atgccaaatatcaataaactgaaaacatgtggaattcattcaaaatacatgagagctatg
tatcctaccaaaaccttcccaaatcattacaccattgtcacgggcttgtatccagagtca
catggcatcattgacaataatatgtatgatgtaaatctcaacaagaatttttcactttct
tcaaaggaacaaaataatccagcctggtggcatgggcaaccaatgtggctgacagcaatg
tatcaaggtttaaaagccgctacctacttttggcccggatcagaagtggctataaatggc
tcctttccttccatatacatgccttacaacggaagtgtcccatttgaagagaggatttct
acactgttaaaatggctggacctgcccaaagctgaaagacccaggttttataccatgtat
tttgaagaacctgattcctctggacatgcaggtggaccagtcagtgccagagtaattaaa
gccttacaggtagtagatcatgcttttgggatgttgatggaaggcctgaagcagcggaat
ttgcacaactgtgtcaatatcatccttctggctgaccatggaatggaccagacttattgt
aacaagatggaatacatgactgattattttcccagaataaacttcttctacatgtacgaa
gggcctgccccccgcatccgagctcataatatacctcatgacttttttagttttaattct
gaggaaattgttagaaacctcagttgccgaaaacctgatcagcatttcaagccctatttg
actcctgatttgccaaagcgactgcactatgccaagaacgtcagaatcgacaaagttcat
ctctttgtggatcaacagtggctggctgttaggagtaaatcaaatacaaattgtggagga
ggcaaccatggttataacaatgagtttaggagcatggaggctatctttctggcacatgga
cccagttttaaagagaagactgaagttgaaccatttgaaaatattgaagtctataaccta
atgtgtgatcttctacgcattcaaccagcaccaaacaatggaacccatggtagtttaaac
catcttctgaaggtgcctttttatgagccatcccatgcagaggaggtgtcaaagttttct
gtttgtggctttgctaatccattgcccacagagtctcttgactgtttctgccctcaccta
caaaatagtactcagctggaacaagtgaatcagatgctaaatctcacccaagaagaaata
acagcaacagtgaaagtaaatttgccatttgggaggcctagggtactgcagaagaacgtg
gaccactgtctcctttaccacagggaatatgtcagtggatttggaaaagctatgaggatg
cccatgtggagttcatacacagtcccccagttgggagacacatcgcctctgcctcccact
gtcccagactgtctgcgggctgatgtcagggttcctccttctgagagccaaaaatgttcc
ttctatttagcagacaagaatatcacccacggcttcctctatcctcctgccagcaataga
acatcagatagccaatatgatgctttaattactagcaatttggtacctatgtatgaagaa
ttcagaaaaatgtgggactacttccacagtgttcttcttataaaacatgccacagaaaga
aatggagtaaatgtggttagtggaccaatatttgattataattatgatggccattttgat
gctccagatgaaattaccaaacatttagccaacactgatgttcccatcccaacacactac
tttgtggtgctgaccagttgtaaaaacaagagccacacaccggaaaactgccctgggtgg
ctggatgtcctaccctttatcatccctcaccgacctaccaacgtggagagctgtcctgaa
ggtaaaccagaagctctttgggttgaagaaagatttacagctcacattgcccgggtccgt
gatgtagaacttctcactgggcttgacttctatcaggataaagtgcagcctgtctctgaa
attttgcaactaaagacatatttaccaacatttgaaaccactatttaa

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (8)   
   KEGG PATHWAY (8)   
Disease (1)   
   OMIM (1)   
Chemical substance (24)   
   KEGG COMPOUND (24)   
Chemical reaction (13)   
   KEGG ENZYME (2)   
   KEGG REACTION (11)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (10)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (8)   
DNA sequence (33)   
   RefSeq(nuc) (9)   
   GenBank (12)   
   EMBL (12)   
3D Structure (2)   
   PDB (2)   
Protein domain (6)   
   Pfam (6)   
All databases (118)   

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