KEGG   Homo sapiens (human): 51727
Entry
51727             CDS       T01001                                 
Symbol
CMPK1, CK, CMK, CMPK, UMK, UMP-CMPK, UMPK
Name
(RefSeq) cytidine/uridine monophosphate kinase 1
  KO
K13800  UMP-CMP kinase [EC:2.7.4.14]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00240  Pyrimidine metabolism
hsa00983  Drug metabolism - other enzymes
hsa01100  Metabolic pathways
hsa01232  Nucleotide metabolism
hsa01240  Biosynthesis of cofactors
Module
hsa_M00052  Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    51727 (CMPK1)
  09111 Xenobiotics biodegradation and metabolism
   00983 Drug metabolism - other enzymes
    51727 (CMPK1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.4  Phosphotransferases with a phosphate group as acceptor
    2.7.4.14  UMP/CMP kinase
     51727 (CMPK1)
SSDB
Motif
Pfam: ADK AAA_17 Thymidylate_kin AAA_18 Zeta_toxin AAA_19 AAA_22
Other DBs
NCBI-GeneID: 51727
NCBI-ProteinID: NP_001129612
OMIM: 191710
HGNC: 18170
Ensembl: ENSG00000162368
UniProt: P30085 A0A494BXC7
Structure
Position
1:47333790..47378839
AA seq 179 aa
MLSRCRSGLLHVLGLSFLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVEEMD
QTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKS
SGRSDDNRESLEKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG
NT seq 540 nt   +upstreamnt  +downstreamnt
atgctgagccgctgccgcagcgggctgctccacgtcctgggccttagcttcctgctgcag
acccgccggccgattctcctctgctctccacgtctcatgaagccgctggtcgtgttcgtc
ctcggcggccccggcgccggcaaggggacccagtgcgcccgcatcgtcgaggaaatggat
cagacaatggctgccaatgctcagaagaataaattcttgattgatgggtttccaagaaat
caagacaaccttcaaggatggaacaagaccatggatgggaaggcagatgtatctttcgtt
ctcttttttgactgtaataatgagatttgtattgaacgatgtcttgagaggggaaagagt
agtggtaggagtgatgacaacagagagagcttggaaaagagaattcagacctaccttcag
tcaacaaagccaattattgacttatatgaagaaatggggaaagtcaagaaaatagatgct
tctaaatctgttgatgaagtttttgatgaagttgtgcagatttttgacaaggaaggctaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (5)   
   KEGG MODULE (1)   
Disease (1)   
   OMIM (1)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (6)   
   KEGG ENZYME (1)   
   KEGG REACTION (5)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
Protein sequence (6)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (35)   
   RefSeq(nuc) (5)   
   GenBank (15)   
   EMBL (15)   
3D Structure (2)   
   PDB (2)   
Protein domain (7)   
   Pfam (7)   
All databases (90)   

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