KEGG   Homo sapiens (human): 5205
Entry
5205              CDS       T01001                                 
Symbol
ATP8B1, ATPIC, BRIC, FIC1, ICP1, PFIC, PFIC1
Name
(RefSeq) ATPase phospholipid transporting 8B1
  KO
K01530  phospholipid-translocating ATPase [EC:7.6.2.1]
Organism
hsa  Homo sapiens (human)
Disease
H00624  Progressive familial intrahepatic cholestasis
H02192  Benign recurrent intrahepatic cholestasis
H02193  Intrahepatic cholestasis of pregnancy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09190 Not Included in Pathway or Brite
  09191 Unclassified: metabolism
   99980 Enzymes with EC numbers
    5205 (ATP8B1)
Enzymes [BR:hsa01000]
 7. Translocases
  7.6  Catalysing the translocation of other compounds
   7.6.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.6.2.1  P-type phospholipid transporter
     5205 (ATP8B1)
SSDB
Motif
Pfam: PhoLip_ATPase_C PhoLip_ATPase_N Cation_ATPase Hydrolase E1-E2_ATPase Hydrolase_3
Other DBs
NCBI-GeneID: 5205
NCBI-ProteinID: NP_005594
OMIM: 602397
HGNC: 3706
Ensembl: ENSG00000081923
UniProt: O43520
Structure
Position
18:complement(57646426..57803315)
AA seq 1251 aa
MSTERDSETTFDEDSQPNDEVVPYSDDETEDELDDQGSAVEPEQNRVNREAEENREPFRK
ECTWQVKANDRKYHEQPHFMNTKFLCIKESKYANNAIKTYKYNAFTFIPMNLFEQFKRAA
NLYFLALLILQAVPQISTLAWYTTLVPLLVVLGVTAIKDLVDDVARHKMDKEINNRTCEV
IKDGRFKVAKWKEIQVGDVIRLKKNDFVPADILLLSSSEPNSLCYVETAELDGETNLKFK
MSLEITDQYLQREDTLATFDGFIECEEPNNRLDKFTGTLFWRNTSFPLDADKILLRGCVI
RNTDFCHGLVIFAGADTKIMKNSGKTRFKRTKIDYLMNYMVYTIFVVLILLSAGLAIGHA
YWEAQVGNSSWYLYDGEDDTPSYRGFLIFWGYIIVLNTMVPISLYVSVEVIRLGQSHFIN
WDLQMYYAEKDTPAKARTTTLNEQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIYGDHR
DASQHNHNKIEQVDFSWNTYADGKLAFYDHYLIEQIQSGKEPEVRQFFFLLAVCHTVMVD
RTDGQLNYQAASPDEGALVNAARNFGFAFLARTQNTITISELGTERTYNVLAILDFNSDR
KRMSIIVRTPEGNIKLYCKGADTVIYERLHRMNPTKQETQDALDIFANETLRTLCLCYKE
IEEKEFTEWNKKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPETISK
LAKADIKIWVLTGDKKETAENIGFACELLTEDTTICYGEDINSLLHARMENQRNRGGVYA
KFAPPVQESFFPPGGNRALIITGSWLNEILLEKKTKRNKILKLKFPRTEEERRMRTQSKR
RLEAKKEQRQKNFVDLACECSAVICCRVTPKQKAMVVDLVKRYKKAITLAIGDGANDVNM
IKTAHIGVGISGQEGMQAVMSSDYSFAQFRYLQRLLLVHGRWSYIRMCKFLRYFFYKNFA
FTLVHFWYSFFNGYSAQTAYEDWFITLYNVLYTSLPVLLMGLLDQDVSDKLSLRFPGLYI
VGQRDLLFNYKRFFVSLLHGVLTSMILFFIPLGAYLQTVGQDGEAPSDYQSFAVTIASAL
VITVNFQIGLDTSYWTFVNAFSIFGSIALYFGIMFDFHSAGIHVLFPSAFQFTGTASNAL
RQPYIWLTIILAVAVCLLPVVAIRFLSMTIWPSESDKIQKHRKRLKAEEQWQRRQQVFRR
GVSTRRSAYAFSHQRGYADLISSGRSIRKKRSPLDAIVADGTAEYRRTGDS
NT seq 3756 nt   +upstreamnt  +downstreamnt
atgagtacagaaagagactcagaaacgacatttgacgaggattctcagcctaatgacgaa
gtggttccctacagtgatgatgaaacagaagatgaacttgatgaccaggggtctgctgtt
gaaccagaacaaaaccgagtcaacagggaagcagaggagaaccgggagccattcagaaaa
gaatgtacatggcaagtcaaagcaaacgatcgcaagtaccacgaacaacctcactttatg
aacacaaaattcttgtgtattaaggagagtaaatatgcgaataatgcaattaaaacatac
aagtacaacgcatttacctttataccaatgaatctgtttgagcagtttaagagagcagcc
aatttatatttcctggctcttcttatcttacaggcagttcctcaaatctctaccctggct
tggtacaccacactagtgcccctgcttgtggtgctgggcgtcactgcaatcaaagacctg
gtggacgatgtggctcgccataaaatggataaggaaatcaacaataggacgtgtgaagtc
attaaggatggcaggttcaaagttgctaagtggaaagaaattcaagttggagacgtcatt
cgtctgaaaaaaaatgattttgttccagctgacattctcctgctgtctagctctgagcct
aacagcctctgctatgtggaaacagcagaactggatggagaaaccaatttaaaatttaag
atgtcacttgaaatcacagaccagtacctccaaagagaagatacattggctacatttgat
ggttttattgaatgtgaagaacccaataacagactagataagtttacaggaacactattt
tggagaaacacaagttttcctttggatgctgataaaattttgttacgtggctgtgtaatt
aggaacaccgatttctgccacggcttagtcatttttgcaggtgctgacactaaaataatg
aagaatagtgggaaaaccagatttaaaagaactaaaattgattacttgatgaactacatg
gtttacacgatctttgttgttcttattctgctttctgctggtcttgccatcggccatgct
tattgggaagcacaggtgggcaattcctcttggtacctctatgatggagaagacgataca
ccctcctaccgtggattcctcattttctggggctatatcattgttctcaacaccatggta
cccatctctctctatgtcagcgtggaagtgattcgtcttggacagagtcacttcatcaac
tgggacctgcaaatgtactatgctgagaaggacacacccgcaaaagctagaaccaccaca
ctcaatgaacagctcgggcagatccattatatcttctctgataagacggggacactcaca
caaaatatcatgacctttaaaaagtgctgtatcaacgggcagatatatggggaccatcgg
gatgcctctcaacacaaccacaacaaaatagagcaagttgattttagctggaatacatat
gctgatgggaagcttgcattttatgaccactatcttattgagcaaatccagtcagggaaa
gagccagaagtacgacagttcttcttcttgctcgcagtttgccacacagtcatggtggat
aggactgatggtcagctcaactaccaggcagcctctcccgatgaaggtgccctggtaaac
gctgccaggaactttggctttgccttcctcgccaggacccagaacaccatcaccatcagt
gaactgggcactgaaaggacttacaatgttcttgccattttggacttcaacagtgaccgg
aagcgaatgtctatcattgtaagaaccccagaaggcaatatcaagctttactgtaaaggt
gctgacactgttatttatgaacggttacatcgaatgaatcctactaagcaagaaacacag
gatgccctggatatctttgcaaatgaaactcttagaaccctatgcctttgctacaaggaa
attgaagaaaaagaatttacagaatggaataaaaagtttatggctgccagtgtggcctcc
accaaccgggacgaagctctggataaagtatatgaggagattgaaaaagacttaattctc
ctgggagctacagctattgaagacaagctacaggatggagttccagaaaccatttcaaaa
cttgcaaaagctgacattaagatctgggtgcttactggagacaaaaaggaaactgctgaa
aatataggatttgcttgtgaacttctgactgaagacaccaccatctgctatggggaggat
attaattctcttcttcatgcaaggatggaaaaccagaggaatagaggtggcgtctacgca
aagtttgcacctcctgtgcaggaatctttttttccacccggtggaaaccgtgccttaatc
atcactggttcttggttgaatgaaattcttctcgagaaaaagaccaagagaaataagatt
ctgaagctgaagttcccaagaacagaagaagaaagacggatgcggacccaaagtaaaagg
aggctagaagctaagaaagagcagcggcagaaaaactttgtggacctggcctgcgagtgc
agcgcagtcatctgctgccgcgtcacccccaagcagaaggccatggtggtggacctggtg
aagaggtacaagaaagccatcacgctggccatcggagatggggccaatgacgtgaacatg
atcaaaactgcccacattggcgttggaataagtggacaagaaggaatgcaagctgtcatg
tcgagtgactattcctttgctcagttccgatatctgcagaggctactgctggtgcatggc
cgatggtcttacataaggatgtgcaagttcctacgatacttcttttacaaaaactttgcc
tttactttggttcatttctggtactccttcttcaatggctactctgcgcagactgcatac
gaggattggttcatcaccctctacaacgtgctgtacaccagcctgcccgtgctcctcatg
gggctgctcgaccaggatgtgagtgacaaactgagcctccgattccctgggttatacata
gtgggacaaagagacttactattcaactataagagattctttgtaagcttgttgcatggg
gtcctaacatcgatgatcctcttcttcatacctcttggagcttatctgcaaaccgtaggg
caggatggagaggcaccttccgactaccagtcttttgccgtcaccattgcctctgctctt
gtaataacagtcaatttccagattggcttggatacttcttattggacttttgtgaatgct
ttttcaatttttggaagcattgcactttattttggcatcatgtttgactttcatagtgct
ggaatacatgttctctttccatctgcatttcaatttacaggcacagcttcaaacgctctg
agacagccatacatttggttaactatcatcctggctgttgctgtgtgcttactacccgtc
gttgccattcgattcctgtcaatgaccatctggccatcagaaagtgataagatccagaag
catcgcaagcggttgaaggcggaggagcagtggcagcgacggcagcaggtgttccgccgg
ggcgtgtcaacgcggcgctcggcctacgccttctcgcaccagcggggctacgcggacctc
atctcctccgggcgcagcatccgcaagaagcgctcgccgcttgatgccatcgtggcggat
ggcaccgcggagtacaggcgcaccggggacagctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Disease (7)   
   KEGG DISEASE (3)   
   OMIM (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (23)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (21)   
DNA sequence (45)   
   RefSeq(nuc) (21)   
   GenBank (12)   
   EMBL (12)   
3D Structure (13)   
   PDB (13)   
Protein domain (6)   
   Pfam (6)   
All databases (118)   

Download RDF
DBGET integrated database retrieval system