KEGG   Homo sapiens (human): 5288
Entry
5288              CDS       T01001                                 
Symbol
PIK3C2G, PI3K-C2-gamma, PI3K-C2GAMMA
Name
(RefSeq) phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
  KO
K00923  phosphatidylinositol-4-phosphate 3-kinase [EC:2.7.1.154]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00562  Inositol phosphate metabolism
hsa01100  Metabolic pathways
hsa04070  Phosphatidylinositol signaling system
hsa05132  Salmonella infection
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    5288 (PIK3C2G)
 09130 Environmental Information Processing
  09132 Signal transduction
   04070 Phosphatidylinositol signaling system
    5288 (PIK3C2G)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    5288 (PIK3C2G)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.154  phosphatidylinositol-4-phosphate 3-kinase
     5288 (PIK3C2G)
SSDB
Motif
Pfam: PI3_PI4_kinase PI3Ka PX PI3K_C2 C2 PI3K_rbd DUF4135 PI4KB-PIK1_PIK AAR2 Serum_albumin
Other DBs
NCBI-GeneID: 5288
NCBI-ProteinID: NP_001275701
OMIM: 609001
HGNC: 8973
Ensembl: ENSG00000139144
UniProt: O75747 B7ZLY6
Structure
Position
12:18242961..18726817
AA seq 1486 aa
MAYSWQTDPNPNESHEKQYEHQEFLFVNQPHSSSQVSLGFDQIVDEISGKIPHYESEIDE
NTFFVPTAPKWDSTGHSLNEAHQISLNEFTSKSRELSWHQVSKAPAIGFSPSVLPKPQNT
NKECSWGSPIGKHHGADDSRFSILAPSFTSLDKINLEKELENENHNYHIGFESSIPPTNS
SFSSDFMPKEENKRSGHVNIVEPSLMLLKGSLQPGMWESTWQKNIESIGCSIQLVEVPQS
SNTSLASFCNKVKKIRERYHAADVNFNSGKIWSTTTAFPYQLFSKTKFNIHIFIDNSTQP
LHFMPCANYLVKDLIAEILHFCTNDQLLPKDHILSVCGSEEFLQNDHCLGSHKMFQKDKS
VIQLHLQKSREAPGKLSRKHEEDHSQFYLNQLLEFMHIWKVSRQCLLTLIRKYDFHLKYL
LKTQENVYNIIEEVKKICSVLGCVETKQITDAVNELSLILQRKGENFYQSSETSAKGLIE
KVTTELSTSIYQLINVYCNSFYADFQPVNVPRCTSYLNPGLPSHLSFTVYAAHNIPETWV
HSYKAFSFTCWLTYAGKKLCQVRNYRNIPDKKLFFFLVNWNETINFPLEIKSLPRESMLT
VKLFGIACATNNANLLAWTCLPLFPKEKSILGSMLFSMTLQSEPPVEMITPGVWDVSQPS
PVTLQIDFPATGWEYMKPDSEENRSNLEEPLKECIKHIARLSQKQTPLLLSEEKKRYLWF
YRFYCNNENCSLPLVLGSAPGWDERTVSEMHTILRRWTFSQPLEALGLLTSSFPDQEIRK
VAVQQLDNLLNDELLEYLPQLVQAVKFEWNLESPLVQLLLHRSLQSIQVAHRLYWLLKNA
ENEAYFKSWYQKLLAALQFCAGKALNDEFSKEQKLIKILGDIGERVKSASDHQRQEVLKK
EIGRLEEFFQDVNTCHLPLNPALCIKGIDHDACSYFTSNALPLKITFINANPMGKNISII
FKAGDDLRQDMLVLQLIQVMDNIWLQEGLDMQMIIYRCLSTGKDQGLVQMVPDAVTLAKI
HRHSGLIGPLKENTIKKWFSQHNHLKADYEKALRNFFYSCAGWCVVTFILGVCDRHNDNI
MLTKSGHMFHIDFGKFLGHAQTFGGIKRDRAPFIFTSEMEYFITEGGKNPQHFQDFVELC
CRAYNIIRKHSQLLLNLLEMMLYAGLPELSGIQDLKYVYNNLRPQDTDLEATSHFTKKIK
ESLECFPVKLNNLIHTLAQMSAISPAKSTSQTFPQESCLLSTTRSIERATILGFSKKSSN
LYLIQVTHSNNETSLTEKSFEQFSKLHSQLQKQFASLTLPEFPHWWHLPFTNSDHRRFRD
LNHYMEQILNVSHEVTNSDCVLSFFLSEAVQQTVEESSPVYLGEKFPDKKPKVQLVISYE
DVKLTILVKHMKNIHLPDGSAPSAHVEFYLLPYPSEVRRRKTKSVPKCTDPTYNEIVVYD
EVTELQGHVLMLIVKSKTVFVGAINIRLCSVPLDKEKWYPLGNSII
NT seq 4461 nt   +upstreamnt  +downstreamnt
atggcatattcttggcaaacggatccaaatcctaatgaatcacacgaaaagcagtatgaa
caccaagaatttctctttgtaaatcaaccccattcttctagccaagtcagtctgggtttt
gatcagatagtagatgagatcagtggcaaaattccacactacgagagtgaaattgatgaa
aacaccttttttgtgcccactgcaccaaaatgggactcaacagggcattcattaaatgaa
gcacaccaaatatccttgaatgaattcacttctaaaagccgtgaactctcctggcatcaa
gttagcaaagcaccagcaattggttttagtccttctgtgttaccaaaacctcaaaatacg
aataaagaatgctcctggggaagccccataggaaaacatcatggtgctgatgattccaga
ttcagtattttagctccatcattcacaagtttggataaaattaatctagagaaagaatta
gaaaatgaaaatcataactaccatataggatttgaaagtagcattcctccaacaaattca
tccttctcaagtgacttcatgccgaaagaagagaataaaaggagtggacatgtgaacatt
gtggaaccatctttgatgcttttgaaaggctctcttcaacccggaatgtgggaaagtaca
tggcagaagaatatagagtcaataggttgttccattcagctagtggaagtacctcaaagc
agcaatacgagtctggcctctttttgcaacaaagtaaaaaaaatcagagaaagatatcat
gcagctgatgttaatttcaattctgggaagatctggagcactactacagcatttccgtat
cagctcttttctaagaccaagtttaatatacatatttttattgataactcaacacaacct
cttcattttatgccatgtgctaattatcttgtcaaagatctaattgcagaaattctgcat
ttttgcacaaatgaccagctactccccaaagatcatattctaagtgtatgtggctctgaa
gaatttttacaaaacgaccactgtttggggagccacaaaatgtttcaaaaagataaatct
gttattcagctccacctgcagaaaagtagggaagctccaggaaagctatctcgaaagcat
gaagaggaccacagtcagttttatctgaatcaacttctagaatttatgcatatttggaaa
gtatccagacaatgtctcttaacactcatcagaaaatatgacttccacctgaaataccta
ttgaaaacccaggaaaacgtgtataatattattgaagaagttaaaaaaatatgcagtgtt
ctagggtgtgtggaaaccaaacaaattacagatgcagtaaatgaactaagtctaattctt
cagagaaaaggagagaatttttatcaaagttcagagacttcagcaaaaggcttgatagag
aaggtaacaactgaactatccacatccatctaccagctaatcaatgtctactgtaacagc
ttttatgcagattttcagcctgtaaatgtacctagatgcacttcctatctaaatcccggg
cttccttcccacctcagcttcacagtgtatgcagcacacaacattccagaaacctgggtg
cacagctacaaagcgttttcttttacctgttggcttacatatgctggaaagaagctgtgc
caagtgagaaactacagaaatattccagacaagaaattattttttttcttggtcaactgg
aatgaaacgatcaattttccccttgaaataaagtcacttccaagggaatccatgctcact
gtaaaactgtttgggattgcctgtgcaaccaacaatgcaaatttactggcgtggacttgt
cttccactgtttccaaaagaaaaatccattctcgggtctatgctgttcagcatgacatta
cagagtgagcctcccgtagaaatgataactccaggagtgtgggatgtaagtcagccatcc
ccggtgaccctgcagattgattttccagctactgggtgggagtatatgaaacctgattct
gaagagaatagaagtaatcttgaagagccactaaaggagtgtataaaacatattgccaga
ctttcacagaaacagactcccctactactctctgaagaaaagaaaagatatttatggttt
tatcgcttctactgcaataatgaaaactgctcccttcctttagtcctgggtagtgcccct
ggatgggatgaaaggactgtttcagaaatgcataccattttgagaagatggacattttct
caacctttagaggctcttgggcttttgacttccagttttccagatcaagaaattcgtaaa
gtggcagttcaacaattagacaacctcttgaatgatgaactactggaatatctcccacag
ctagttcaggctgtcaagtttgaatggaaccttgagagtcctttagtgcaacttctactc
caccgctccttgcagagcatccaggttgcccatcgtctttactggctgctaaaaaatgca
gaaaatgaagcttattttaaaagctggtatcagaagctactagctgctctccaattctgt
gcaggtaaagccttgaatgatgagttttccaaggagcagaaacttatcaaaattctggga
gatattggggaaagagtcaagtctgccagtgaccatcaaagacaggaggtactgaagaaa
gaaattggcagactagaagagttctttcaagatgtaaatacttgtcatcttcctctgaac
cctgccctatgtataaaagggattgatcacgatgcatgttcatattttacatctaatgct
ttgccattgaagattactttcatcaatgctaatccgatgggcaaaaacatcagcattatt
tttaaggctggagatgatcttcgtcaggatatgcttgttctgcagcttattcaagtgatg
gacaatatttggctgcaggaaggcttggatatgcaaatgatcatttatagatgtctatcc
acaggaaaagaccaaggattggtgcagatggtacctgatgctgtgaccctagcaaagatt
catcgccattctggactgataggaccattgaaagaaaatacaattaaaaagtggttcagt
cagcacaaccacttaaaggcagattatgaaaaggccttgaggaactttttctactcctgt
gctggctggtgtgtggtaacattcatcctgggagtatgtgaccgtcacaatgataatatc
atgctgacaaagtcgggccacatgtttcatattgactttggaaaattcttaggtcatgca
caaacatttggagggataaaaagggaccgagctcctttcatttttacttcagagatggaa
tactttattacagagggtgggaaaaacccacagcattttcaagattttgtggaactttgc
tgtcgtgcttataatattatcagaaagcacagccaactgctcttgaacctgctggaaatg
atgctgtatgcaggactgcctgagctaagtggaattcaagacctgaaatatgtgtataat
aatcttcgtccacaagacacagacctggaagcaacaagtcattttaccaagaaaataaag
gaaagtctggagtgtttccctgttaaattgaataacttgatccacacacttgcacaaatg
tcagccataagccctgccaaatctacttcacagacttttcctcaggaatcctgtttgctg
agtacaactaggtcgattgaaagagcaacaattttagggttcagcaagaaatccagtaat
ctgtatctgatccaggtgacacacagcaacaacgaaacaagcctgacagaaaaatcattt
gagcagttttcaaaacttcacagccaacttcagaagcagtttgcatcactgactctccca
gagtttcctcattggtggcacctaccttttacaaattcagatcacagaagattcagagat
ctaaatcattacatggaacagatattaaatgtatcacatgaagttacaaacagtgattgt
gtacttagctttttcctctctgaggctgtgcaacaaacagttgaagaatcatcacctgtg
tacctaggtgagaagtttccagacaagaagcctaaggtgcagttagtcatatcctacgag
gatgtgaagctgaccatactagtgaaacacatgaaaaacattcatctcccagatggctct
gcgcccagtgcacatgttgaattttatcttttaccatatcccagtgaagttcgtaggagg
aaaacaaaatctgttccaaaatgtacggaccccacttacaatgaaattgtagtatatgat
gaagtcacagagctccaaggacatgtcttaatgcttattgtgaagagtaaaactgtattt
gtgggagcaattaacatccgactctgtagtgtcccactcgataaagaaaaatggtatcca
ttaggaaacagtataatttga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Disease (1)   
   OMIM (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (36)   
   KEGG ORTHOLOGY (1)   
   RefGene (30)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (35)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (32)   
DNA sequence (46)   
   RefSeq(nuc) (34)   
   GenBank (6)   
   EMBL (6)   
3D Structure (1)   
   PDB (1)   
Protein domain (10)   
   Pfam (10)   
All databases (145)   

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