KEGG   Homo sapiens (human): 5298
Entry
5298              CDS       T01001                                 
Symbol
PI4KB, DFNA87, NPIK, PI4K-BETA, PI4K92, PI4KBETA, PI4KIII, PI4KIIIBETA, PIK4CB
Name
(RefSeq) phosphatidylinositol 4-kinase beta
  KO
K19801  phosphatidylinositol 4-kinase B [EC:2.7.1.67]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00562  Inositol phosphate metabolism
hsa01100  Metabolic pathways
hsa04070  Phosphatidylinositol signaling system
Module
hsa_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Disease
H00604  Deafness, autosomal dominant
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    5298 (PI4KB)
 09130 Environmental Information Processing
  09132 Signal transduction
   04070 Phosphatidylinositol signaling system
    5298 (PI4KB)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.67  1-phosphatidylinositol 4-kinase
     5298 (PI4KB)
SSDB
Motif
Pfam: PI3_PI4_kinase PI4KB-PIK1_PIK DUF4135 ABC1
Other DBs
NCBI-GeneID: 5298
NCBI-ProteinID: NP_001317650
OMIM: 602758
HGNC: 8984
Ensembl: ENSG00000143393
UniProt: Q9UBF8
Structure
Position
1:complement(151291797..151327715)
AA seq 816 aa
MGDTVVEPAPLKPTSEPTSGPPGNNGGSLLSVITEGVGELSVIDPEVAQKACQEVLEKVK
LLHGGVAVSSRGTPLELVNGDGVDSEIRCLDDPPAQIREEEDEMGAAVASGTAKGARRRR
QNNSAKQSWLLRLFESKLFDISMAISYLYNSKEPGVQAYIGNRLFCFRNEDVDFYLPQLL
NMYIHMDEDVGDAIKPYIVHRCRQSINFSLQCALLLGAYSSDMHISTQRHSRGTKLRKLI
LSDELKPAHRKRELPSLSPAPDTGLSPSKRTHQRSKSDATASISLSSNLKRTASNPKVEN
EDEELSSSTESIDNSFSSPVRLAPEREFIKSLMAIGKRLATLPTKEQKTQRLISELSLLN
HKLPARVWLPTAGFDHHVVRVPHTQAVVLNSKDKAPYLIYVEVLECENFDTTSVPARIPE
NRIRSTRSVENLPECGITHEQRAGSFSTVPNYDNDDEAWSVDDIGELQVELPEVHTNSCD
NISQFSVDSITSQESKEPVFIAAGDIRRRLSEQLAHTPTAFKRDPEDPSAVALKEPWQEK
VRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYKI
LVISADSGMIEPVVNAVSIHQVKKQSQLSLLDYFLQEHGSYTTEAFLSAQRNFVQSCAGY
CLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSSPRNLGFETSAFKLTTEFVDVMGG
LDGDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGSQLPCFHGSSTIRNLKERFHMSM
TEEQLQLLVEQMVDGSMRSITTKLYDGFQYLTNGIM
NT seq 2451 nt   +upstreamnt  +downstreamnt
atgggagatacagtagtggagcctgcccccttgaagccaacttctgagcccacttctggc
ccaccagggaataatggggggtccctgctaagtgtcatcacggagggggtcggggaacta
tcagtgattgaccctgaggtggcccagaaggcctgccaggaggtgttggagaaagtcaag
cttttgcatggaggcgtggcagtctctagcagaggcaccccactggagttggtcaatggg
gatggtgtggacagtgagatccgttgcctagatgatccacctgcccagatcagggaggag
gaagatgagatgggggccgctgtggcctcaggcacagccaaaggagcaagaagacggcgg
cagaacaactcagctaaacagtcttggctgctgaggctgtttgagtcaaaactgtttgac
atctccatggccatttcatacctgtataactccaaggagcctggagtacaagcctacatt
ggcaaccggctcttctgctttcgcaacgaggacgtggacttctatctgccccagttgctt
aacatgtacatccacatggatgaggacgtgggtgatgccattaagccctacatagtccac
cgttgccgccagagcattaacttttccctccagtgtgccctgttgcttggggcctattct
tcagacatgcacatttccactcaacgacactcccgtgggaccaagctacggaagctgatc
ctctcagatgagctaaagccagctcacaggaagagggagctgccctccttgagcccggcc
cctgacacagggctgtctccctccaaaaggactcaccagcgctctaagtcagatgccact
gccagcataagtctcagcagcaacctgaaacgaacagccagcaaccctaaagtggagaat
gaggatgaggagctctcctccagcaccgagagtattgataattcattcagttcccctgtt
cgactggctcctgagagagaattcatcaagtccctgatggcgatcggcaagcggctggcc
acgctccccaccaaagagcagaaaacacagaggctgatctcagagctctccctgctcaac
cataagctccctgcccgagtctggctgcccactgctggctttgaccaccacgtggtccgt
gtaccccacacacaggctgttgtcctcaactccaaggacaaggctccctacctgatttat
gtggaagtccttgaatgtgaaaactttgacaccaccagtgtccctgcccggatccccgag
aaccgaattcggagtacgaggtccgtagaaaacttgcccgaatgtggtattacccatgag
cagcgagctggcagcttcagcactgtgcccaactatgacaacgatgatgaggcctggtcg
gtggatgacataggcgagctgcaagtggagctccccgaagtgcataccaacagctgtgac
aacatctcccagttctctgtggacagcatcaccagccaggagagcaaggagcctgtgttc
attgcagcaggggacatccgccggcgcctttcggaacagctggctcataccccgacagcc
ttcaaacgagacccagaagatccttctgcagttgctctcaaagagccctggcaggagaaa
gtacggcggatcagagagggctccccctacggccatctccccaattggcggctcctgtca
gtcattgtcaagtgtggggatgaccttcggcaagagcttctggcctttcaggtgttgaag
caactgcagtccatttgggaacaggagcgagtgcccctttggatcaagccatacaagatt
cttgtgatttcggctgatagtggcatgattgaaccagtggtcaatgctgtgtccatccat
caggtgaagaaacagtcacagctctccttgctcgattacttcctacaggagcacggcagt
tacaccactgaggcattcctcagtgcacagcgcaattttgtgcaaagttgtgctgggtac
tgcttggtctgctacctgctgcaagtcaaggacagacacaatgggaatatccttttggac
gcagaaggccacatcatccacatcgactttggcttcatcctctccagctcaccccgaaat
ctgggctttgagacgtcagcctttaagctgaccacagagtttgtggatgtgatgggcggc
ctggatggcgacatgttcaactactataagatgctgatgctgcaagggctgattgccgct
cggaaacacatggacaaggtggtgcagatcgtggagatcatgcagcaaggttctcagctt
ccttgcttccatggctccagcaccattcgaaacctcaaagagaggttccacatgagcatg
actgaggagcagctgcagctgctggtggagcagatggtggatggcagtatgcggtctatc
accaccaaactctatgacggcttccagtacctcaccaacggcatcatgtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (12)   
   OC (1)   
Protein sequence (23)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (21)   
DNA sequence (43)   
   RefSeq(nuc) (21)   
   GenBank (11)   
   EMBL (11)   
3D Structure (16)   
   PDB (16)   
Protein domain (4)   
   Pfam (4)   
All databases (123)   

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