KEGG   Homo sapiens (human): 53349
Entry
53349             CDS       T01001                                 
Symbol
ZFYVE1, DFCP1, PPP1R172, SR3, TAFF1, ZNFN2A1
Name
(RefSeq) zinc finger FYVE-type containing 1
  KO
K17603  zinc finger FYVE domain-containing protein 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04140  Autophagy - animal
hsa05022  Pathways of neurodegeneration - multiple diseases
Network
nt06532  Autophagy
  Element
N01715  Autophagy-vesicle nucleation/elongation/maturation, PI3P synthesis by PI3KC3-C1
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    53349 (ZFYVE1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05022 Pathways of neurodegeneration - multiple diseases
    53349 (ZFYVE1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    53349 (ZFYVE1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    53349 (ZFYVE1)
   03029 Mitochondrial biogenesis [BR:hsa03029]
    53349 (ZFYVE1)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     53349 (ZFYVE1)
Membrane trafficking [BR:hsa04131]
 Autophagy
  Other autophagy associated proteins
   Others
    53349 (ZFYVE1)
Mitochondrial biogenesis [BR:hsa03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Other mitophagy factors
    53349 (ZFYVE1)
SSDB
Motif
Pfam: FYVE GBP zf-B_box AIG1 MMR_HSR1 DUF429
Other DBs
NCBI-GeneID: 53349
NCBI-ProteinID: NP_067083
OMIM: 605471
HGNC: 13180
Ensembl: ENSG00000165861
UniProt: Q9HBF4
Position
14:complement(72969445..73027106)
AA seq 777 aa
MSAQTSPAEKGLNPGLMCQESYACSGTDEAIFECDECCSLQCLRCEEELHRQERLRNHER
IRLKPGHVPYCDLCKGLSGHLPGVRQRAIVRCQTCKINLCLECQKRTHSGGNKRRHPVTV
YNVSNLQESLEAEEMDEETKRKKMTEKVVSFLLVDENEEIQVTNEEDFIRKLDCKPDQHL
KVVSIFGNTGDGKSHTLNHTFFYGREVFKTSPTQESCTVGVWAAYDPVHKVAVIDTEGLL
GATVNLSQRTRLLLKVLAISDLVIYRTHADRLHNDLFKFLGDASEAYLKHFTKELKATTA
RCGLDVPLSTLGPAVIIFHETVHTQLLGSDHPSEVPEKLIQDRFRKLGRFPEAFSSIHYK
GTRTYNPPTDFSGLRRALEQLLENNTTRSPRHPGVIFKALKALSDRFSGEIPDDQMAHSS
FFPDEYFTCSSLCLSCGVGCKKSMNHGKEGVPHEAKSRCRYSHQYDNRVYTCKACYERGE
EVSVVPKTSASTDSPWMGLAKYAWSGYVIECPNCGVVYRSRQYWFGNQDPVDTVVRTEIV
HVWPGTDGFLKDNNNAAQRLLDGMNFMAQSVSELSLGPTKAVTSWLTDQIAPAYWRPNSQ
ILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNCYEARNV
QLAVTEAQVDDEGGTLIARKVGEAVQNTLGAVVTAIDIPLGLVKDAARPAYWVPDHEILH
CHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPVRVCFNCNKKPGDL
NT seq 2334 nt   +upstreamnt  +downstreamnt
atgagtgcccagacttccccagcagagaagggcctgaatccggggctgatgtgccaggaa
agttacgcttgcagcgggactgatgaagctatctttgagtgtgatgagtgctgcagtctg
cagtgtctccgctgcgaggaggagctccatcggcaggagcgcctgagaaaccatgagcgg
ataagactcaaacctggccatgtcccttactgtgacctctgcaagggtctcagtgggcat
ttaccaggtgttaggcagagggcaatagtgaggtgccagacctgcaaaattaacttgtgc
ctggagtgccagaagaggactcattctgggggtaacaaaaggagacaccctgttactgtg
tacaatgtcagtaatctccaggagtcactggaggcagaagagatggatgaggagaccaag
aggaagaagatgactgagaaggttgtgagtttcctcctagtagacgaaaatgaagaaatt
caggtaacaaatgaagaagactttattagaaaattggactgcaaacctgatcagcatctg
aaagtggtttccatttttggaaatactggtgatggaaagtctcatactctcaaccacact
ttcttttatggtcgtgaagtctttaaaacctccccgacccaggagtcctgcactgtggga
gtgtgggcagcctatgacccagttcacaaagtagcagtgatcgatacggaagggctcctg
ggggccaccgtgaatctaagccagagaacacggctgctgcttaaggtcctggccatctca
gacctcgtcatctatcgaactcatgcagaccggctgcataacgacctcttcaaattcctt
ggggatgcctcagaagcttatctgaagcacttcaccaaggagctcaaggccaccactgct
cgctgtggcctggatgtccctttatccacactgggccctgcagttatcatcttccatgag
accgtgcacacccagctactgggctctgatcatccctcagaggtgccagagaagctcatc
caggaccggttccggaagctgggccgtttccctgaagcctttagttccattcactacaag
ggaacgaggacttacaaccctcccacggacttttctgggcttcggcgtgctttggagcag
ctactagagaataacaccacccgttctccccggcacccgggagtcatcttcaaagccctg
aaggcactaagtgaccgcttcagcggtgagatccccgatgaccagatggcgcacagctcc
ttttttccagatgagtatttcacctgctcctccttgtgcctcagctgtggggttggatgt
aagaaaagcatgaatcatgggaaggaaggagtgcctcatgaagccaagagccgctgcaga
tactcccaccagtatgacaaccgagtgtatacctgcaaggcctgctatgagagaggcgag
gaagtcagtgtagtgcccaaaacatctgcttccactgactccccctggatgggtctcgca
aaatatgcctggtctgggtatgtgatcgaatgtcctaactgtggcgtggtctatcgtagt
cggcagtactggtttggaaaccaagatcctgtggatacggtggtgcggacagagattgtg
catgtgtggcctggaactgatgggtttctgaaggacaacaacaatgctgcccagcgcctg
ttggacgggatgaacttcatggctcagtcggtgtccgagcttagccttggacccaccaag
gctgtgacttcctggctgacagaccagatcgcccctgcctactggaggcccaactcccag
attctgagctgcaacaagtgtgcgacgtcctttaaagataacgacactaagcatcactgc
cgagcctgtggggagggcttctgtgacagctgttcatcaaagactcggccagtgcctgag
cggggctggggccctgcgccagtgcgggtctgtgacaactgctacgaagccaggaacgtc
cagttagctgttaccgaggcacaagtggacgatgaaggtggaacgctcattgctcggaag
gtgggcgaggccgtgcagaacactctgggagccgtggtgacagccattgacataccacta
ggtctggtaaaggacgcggccaggcctgcgtactgggtgcctgaccacgaaatcctccac
tgccacaactgccggaaggagttcagcatcaagctctccaagcaccactgccgggcctgc
ggacagggcttctgtgatgagtgctcccatgaccgccgggctgttccttctcgtggctgg
gaccatcccgtccgagtctgcttcaactgcaataaaaagcccggtgacctttaa

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (2)   
   KEGG PATHWAY (2)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (25)   
   KEGG ORTHOLOGY (1)   
   RefGene (16)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (12)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (10)   
DNA sequence (46)   
   RefSeq(nuc) (10)   
   GenBank (18)   
   EMBL (18)   
Protein domain (6)   
   Pfam (6)   
All databases (99)   

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