KEGG   Homo sapiens (human): 5351
Entry
5351              CDS       T01001                                 
Symbol
PLOD1, EDS6, EDSKCL1, LH, LH1, LLH, PLOD
Name
(RefSeq) procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
  KO
K00473  procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 [EC:1.14.11.4]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00310  Lysine degradation
hsa01100  Metabolic pathways
Disease
H00980  Nevo syndrome
H02245  Ehlers-Danlos syndrome kyphoscoliosis type
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    5351 (PLOD1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    5351 (PLOD1)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.11  With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
    1.14.11.4  procollagen-lysine 5-dioxygenase
     5351 (PLOD1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   5351 (PLOD1)
SSDB
Motif
Pfam: 2OG-FeII_Oxy Anp1 2OG-FeII_Oxy_3 DDE_3
Other DBs
NCBI-GeneID: 5351
NCBI-ProteinID: NP_000293
OMIM: 153454
HGNC: 9081
Ensembl: ENSG00000083444
UniProt: Q02809
Position
1:11934717..11975537
AA seq 727 aa
MRPLLLLALLGWLLLAEAKGDAKPEDNLLVLTVATKETEGFRRFKRSAQFFNYKIQALGL
GEDWNVEKGTSAGGGQKVRLLKKALEKHADKEDLVILFADSYDVLFASGPRELLKKFRQA
RSQVVFSAEELIYPDRRLETKYPVVSDGKRFLGSGGFIGYAPNLSKLVAEWEGQDSDSDQ
LFYTKIFLDPEKREQINITLDHRCRIFQNLDGALDEVVLKFEMGHVRARNLAYDTLPVLI
HGNGPTKLQLNYLGNYIPRFWTFETGCTVCDEGLRSLKGIGDEALPTVLVGVFIEQPTPF
VSLFFQRLLRLHYPQKHMRLFIHNHEQHHKAQVEEFLAQHGSEYQSVKLVGPEVRMANAD
ARNMGADLCRQDRSCTYYFSVDADVALTEPNSLRLLIQQNKNVIAPLMTRHGRLWSNFWG
ALSADGYYARSEDYVDIVQGRRVGVWNVPYISNIYLIKGSALRGELQSSDLFHHSKLDPD
MAFCANIRQQDVFMFLTNRHTLGHLLSLDSYRTTHLHNDLWEVFSNPEDWKEKYIHQNYT
KALAGKLVETPCPDVYWFPIFTEVACDELVEEMEHFGQWSLGNNKDNRIQGGYENVPTID
IHMNQIGFEREWHKFLLEYIAPMTEKLYPGYYTRAQFDLAFVVRYKPDEQPSLMPHHDAS
TFTINIALNRVGVDYEGGGCRFLRYNCSIRAPRKGWTLMHPGRLTHYHEGLPTTRGTRYI
AVSFVDP
NT seq 2184 nt   +upstreamnt  +downstreamnt
atgcggcccctgctgctactggccctgctgggctggctgctgctggccgaagcgaagggc
gacgccaagccggaggacaaccttttagtcctcacggtggccactaaggagaccgaggga
ttccgtcgcttcaagcgctcagctcagttcttcaactacaagatccaggcgcttggccta
ggggaggactggaatgtggagaaggggacgtcggcaggtggagggcagaaggtccggctg
ctgaagaaagctctggagaagcacgcagacaaggaggatctggtcattctcttcgcagac
agctatgacgtgctgtttgcatcggggccccgggagctcctgaagaagttccggcaggcc
aggagccaggtggtcttctctgctgaggagctcatctacccagaccgcaggctggagacc
aagtatccggtggtgtccgatggcaagaggttcctgggctctggaggcttcatcggttat
gcccccaacctcagcaaactggtggccgagtgggagggccaggacagcgacagcgatcag
ctgttttacaccaagatcttcttggacccggagaagagggagcagatcaatatcaccctg
gaccaccgctgccgtatcttccagaacctggatggagccttggatgaggtcgtgctcaag
tttgaaatgggccatgtgagagcgaggaacctggcctatgacaccctcccggtcctgatc
catggcaacgggccaaccaagctgcagttgaactacctgggcaactacatcccgcgcttc
tggaccttcgaaacaggctgcaccgtgtgtgacgaaggcttgcgcagcctcaagggcatt
ggggatgaagctctgcccacggtcctggtcggcgtgttcatcgaacagcccacgccgttt
gtgtccctgttcttccagcggctcctgcggctccactacccccagaaacacatgcgactt
ttcatccacaaccacgagcagcaccacaaggctcaggtggaagagttcctggcacagcat
ggcagcgagtaccagtctgtgaagctggtgggccctgaggtgcggatggcgaatgcagat
gccaggaacatgggcgcagacctgtgccggcaggaccgcagctgcacctactacttcagc
gtggatgctgacgtggccctgaccgagcccaacagcctgcggctgctgatccaacagaac
aagaacgtcattgccccgctgatgacccggcatgggaggctgtggtcgaacttctggggg
gctctcagtgcagatggctactatgcccgttccgaggactacgtggacattgtgcagggg
cggcgtgttggtgtctggaatgtgccctatatttcaaacatctacttgatcaagggcagt
gccctgcggggtgagctgcagtcctcagatctcttccaccacagcaagctggaccccgac
atggccttctgtgccaacatccggcagcaggatgtgttcatgttcctgaccaaccggcac
acccttggccatctgctctccctagacagctaccgcaccacccacctgcacaacgacctc
tgggaggtgttcagcaaccccgaggactggaaggagaagtacatccaccagaactacacc
aaagccctggcagggaagctggtggagacgccctgcccggatgtctattggttccccatc
ttcacggaggtggcctgtgatgagctggtggaggagatggagcactttggccagtggtct
ctgggcaacaacaaggacaaccgcatccagggtggctacgagaacgtgccgactattgac
atccacatgaaccagatcggctttgagcgggagtggcacaaattcctgctggagtacatt
gcgcccatgacggagaagctctaccccggctactacaccagggcccagtttgacctggcc
tttgtcgtccgctacaagcctgatgagcagccctcactgatgccacaccatgatgcctcc
accttcaccatcaacatcgccctgaaccgagtcggggtggattacgagggcgggggctgt
cggttcctgcgctacaactgttccatccgagccccaaggaagggctggaccctcatgcac
cctggacgactcacgcattaccatgaggggctccccaccaccaggggcacccgctacatc
gcagtctccttcgtcgatccctaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (4)   
   KEGG DISEASE (2)   
   OMIM (2)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (28)   
   RefSeq(nuc) (2)   
   GenBank (13)   
   EMBL (13)   
Protein domain (4)   
   Pfam (4)   
All databases (67)   

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