KEGG   Homo sapiens (human): 53637
Entry
53637             CDS       T01001                                 
Symbol
S1PR5, EDG8, Edg-8, S1P5, SPPR-1, SPPR-2
Name
(RefSeq) sphingosine-1-phosphate receptor 5
  KO
K04295  sphingosine 1-phosphate receptor 5
Organism
hsa  Homo sapiens (human)
Pathway
hsa04071  Sphingolipid signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
Drug target
Amiselimod (DG02399): D10904 D10905
Etrasimod (DG02444): D10930 D10931<US>
Ozanimod (DG02827): D10967<US> D10968
Siponimod (DG03018): D11072<JP/US> D11460
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04071 Sphingolipid signaling pathway
    53637 (S1PR5)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    53637 (S1PR5)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    53637 (S1PR5)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Lipid
   Sphingolipid
    53637 (S1PR5)
SSDB
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx
Other DBs
NCBI-GeneID: 53637
NCBI-ProteinID: NP_001159687
OMIM: 605146
HGNC: 14299
Ensembl: ENSG00000180739
UniProt: Q9H228
Structure
Position
19:complement(10512742..10517965)
AA seq 398 aa
MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFIVLENLAVLLV
LGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFAREGGVFVALT
ASVLSLLAIALERSLTMARRGPAPVSSRGRTLAMAAAAWGVSLLLGLLPALGWNCLGRLD
ACSTVLPLYAKAYVLFCVLAFVGILAAICALYARIYCQVRANARRLPARPGTAGTTSTRA
RRKPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQADPFLGLAMANSL
LNPIIYTLTNRDLRHALLRLVCCGRHSCGRDPSGSQQSASAAEASGGLRRCLPPGLDGSF
SGSERSSPQRDGLDTSGSTGSPGAPTAARTLVSEPAAD
NT seq 1197 nt   +upstreamnt  +downstreamnt
atggagtcggggctgctgcggccggcgccggtgagcgaggtcatcgtcctgcattacaac
tacaccggcaagctccgcggtgcgcgctaccagccgggtgccggcctgcgcgccgacgcc
gtggtgtgcctggcggtgtgcgccttcatcgtgctagagaatctagccgtgttgttggtg
ctcggacgccacccgcgcttccacgctcccatgttcctgctcctgggcagcctcacgttg
tcggatctgctggcaggcgccgcctacgccgccaacatcctactgtcggggccgctcacg
ctgaaactgtcccccgcgctctggttcgcacgggagggaggcgtcttcgtggcactcact
gcgtccgtgctgagcctcctggccatcgcgctggagcgcagcctcaccatggcgcgcagg
gggcccgcgcccgtctccagtcgggggcgcacgctggcgatggcagccgcggcctggggc
gtgtcgctgctcctcgggctcctgccagcgctgggctggaattgcctgggtcgcctggac
gcttgctccactgtcttgccgctctacgccaaggcctacgtgctcttctgcgtgctcgcc
ttcgtgggcatcctggccgctatctgtgcactctacgcgcgcatctactgccaggtacgc
gccaacgcgcggcgcctgccggcacggcccgggactgcggggaccacctcgacccgggcg
cgtcgcaagccgcgctcgctggccttgctgcgcacgctcagcgtggtgctcctggccttt
gtggcatgttggggccccctcttcctgctgctgttgctcgacgtggcgtgcccggcgcgc
acctgtcctgtactcctgcaggccgatcccttcctgggactggccatggccaactcactt
ctgaaccccatcatctacacgctcaccaaccgcgacctgcgccacgcgctcctgcgcctg
gtctgctgcggacgccactcctgcggcagagacccgagtggctcccagcagtcggcgagc
gcggctgaggcttccgggggcctgcgccgctgcctgcccccgggccttgatgggagcttc
agcggctcggagcgctcatcgccccagcgcgacgggctggacaccagcggctccacaggc
agccccggtgcacccacagccgcccggactctggtatcagaaccggctgcagactga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Drug (8)   
   KEGG DRUG (8)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (24)   
   RefSeq(nuc) (2)   
   GenBank (11)   
   EMBL (11)   
3D Structure (2)   
   PDB (2)   
Protein domain (2)   
   Pfam (2)   
All databases (68)   

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