KEGG   Homo sapiens (human): 5408
Entry
5408              CDS       T01001                                 
Symbol
PNLIPRP2, PLRP2
Name
(RefSeq) pancreatic lipase related protein 2 (gene/pseudogene)
  KO
K14075  pancreatic lipase-related protein 2 [EC:3.1.1.3]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00561  Glycerolipid metabolism
hsa01100  Metabolic pathways
hsa04972  Pancreatic secretion
hsa04975  Fat digestion and absorption
Module
hsa_M00098  Acylglycerol degradation
Drug target
Orlistat: D04028<US>
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00561 Glycerolipid metabolism
    5408 (PNLIPRP2)
 09150 Organismal Systems
  09154 Digestive system
   04972 Pancreatic secretion
    5408 (PNLIPRP2)
   04975 Fat digestion and absorption
    5408 (PNLIPRP2)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.3  triacylglycerol lipase
     5408 (PNLIPRP2)
SSDB
Motif
Pfam: Lipase PLAT Abhydrolase_6 Abhydrolase_1 Retrotran_gag_3 BD-FAE Abhydrolase_3 Ser_hydrolase Hydrolase_4
Other DBs
NCBI-GeneID: 5408
NCBI-ProteinID: NP_005387
OMIM: 604423
HGNC: 9157
Ensembl: ENSG00000266200
UniProt: P54317
Structure
Position
10:116620953..116645143
AA seq 469 aa
MLPPWTLGLLLLATVRGKEVCYGQLGCFSDEKPWAGTLQRPVKLLPWSPEDIDTRFLLYT
NENPNNFQLITGTEPDTIEASNFQLDRKTRFIIHGFLDKAEDSWPSDMCKKMFEVEKVNC
ICVDWRHGSRAMYTQAVQNIRVVGAETAFLIQALSTQLGYSLEDVHVIGHSLGAHTAAEA
GRRLGGRVGRITGLDPAGPCFQDEPEEVRLDPSDAVFVDVIHTDSSPIVPSLGFGMSQKV
GHLDFFPNGGKEMPGCKKNVLSTITDIDGIWEGIGGFVSCNHLRSFEYYSSSVLNPDGFL
GYPCASYDEFQESKCFPCPAEGCPKMGHYADQFKGKTSAVEQTFFLNTGESGNFTSWRYK
VSVTLSGKEKVNGYIRIALYGSNENSKQYEIFKGSLKPDASHTCAIDVDFNVGKIQKVKF
LWNKRGINLSEPKLGASQITVQSGEDGTEYNFCSSDTVEENVLQSLYPC
NT seq 1410 nt   +upstreamnt  +downstreamnt
atgctgcccccttggaccctcggccttctcctgctggccacagtcagaggaaaagaggtc
tgctacggacaacttggctgcttttctgatgaaaaaccatgggcaggaacccttcagcga
cctgtaaaattacttccctggtcccccgaggacattgacacccgctttcttctgtacaca
aatgaaaatccaaacaacttccaactaatcactggcacggaaccagacaccattgaggct
tcaaacttccaactggaccgcaagacacgcttcatcatccatggcttcttagacaaggcg
gaggacagctggccatcggacatgtgcaagaaaatgtttgaagtggagaaggtgaactgc
atctgtgtggactggaggcacgggtcccgggcaatgtacacccaagccgtgcaaaacatt
cgggttgttggggcggagacagctttcttaatacaagcactgtcgacgcagctagggtac
agccttgaggacgtgcatgtcatcggccacagcctgggcgcgcacacggccgcggaggcg
ggcaggaggctggggggccgcgtgggcaggatcacagggctggatccagcagggccgtgc
ttccaggatgaacctgaggaggttcggttggatccatctgacgccgtgtttgtggatgtg
attcacacagattcttctcccatagttccttccctaggtttcggaatgagccaaaaggtg
ggccatctggatttctttccaaatggaggaaaggaaatgcccggatgtaagaaaaatgtc
ctttcaaccattactgatattgatggaatatgggaaggaattggtggctttgtgtcttgc
aatcacctaagaagcttcgagtattactcaagcagcgtcctcaaccctgatggcttcctg
ggctatccctgtgcctcctacgatgagtttcaggagagtaagtgtttcccttgtccagct
gaaggatgccccaaaatggggcactatgctgaccaatttaaggggaaaacaagtgctgtg
gaacaaacctttttcctgaacacaggagagagtggtaactttactagttggagatataag
gtatcagtcacactttctggaaaagagaaagtgaatgggtacatcaggattgctttgtat
ggaagtaatgaaaactcaaaacaatatgagattttcaaaggatccctcaaaccagatgca
agtcacacgtgtgctattgatgtggattttaatgttggaaaaatacagaaagttaaattc
ctctggaacaaacgtgggataaatctatctgagcccaaactgggggcttcccaaatcaca
gtgcaaagtggtgaagatgggactgagtataatttttgtagcagcgacactgtggaagaa
aacgtcttgcaatctctttacccttgttaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Disease (1)   
   OMIM (1)   
Drug (1)   
   KEGG DRUG (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (26)   
   RefSeq(nuc) (2)   
   GenBank (12)   
   EMBL (12)   
3D Structure (2)   
   PDB (2)   
Protein domain (9)   
   Pfam (9)   
All databases (76)   

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