KEGG   Homo sapiens (human): 5447
Entry
5447              CDS       T01001                                 
Symbol
POR, CPR, CYPOR, P450R
Name
(RefSeq) cytochrome p450 oxidoreductase
  KO
K00327  NADPH-ferrihemoprotein reductase [EC:1.6.2.4]
Organism
hsa  Homo sapiens (human)
Disease
H00458  Syndromic craniosynostoses
H01753  Antley-Bixler syndrome
H02315  Disordered steroidogenesis due to cytochrome P450 oxidoreductase
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09190 Not Included in Pathway or Brite
  09191 Unclassified: metabolism
   99980 Enzymes with EC numbers
    5447 (POR)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.6  Acting on NADH or NADPH
   1.6.2  With a heme protein as acceptor
    1.6.2.4  NADPH---hemoprotein reductase
     5447 (POR)
SSDB
Motif
Pfam: FAD_binding_1 Flavodoxin_1 NAD_binding_1
Other DBs
NCBI-GeneID: 5447
NCBI-ProteinID: NP_001354491
OMIM: 124015
HGNC: 9208
Ensembl: ENSG00000127948
Position
7:75915155..75986855
AA seq 677 aa
MGDSHVDTSSTVSEAVAEEVSLFSMTDMILFSLIVGLLTYWFLFRKKKEEVPEFTKIQTL
TSSVRESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLA
DLSSLPEIDNALVVFCMATYGEGDPTDNAQDFYDWLQETDVDLSGVKFAVFGLGNKTYEH
FNAMGKYVDKRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEHFGVEATGEES
SIRQYELVVHTDIDAAKVYMGEMGRLKSYENQKPPFDAKNPFLAAVTTNRKLNQGTERHL
MHLELDISDSKIRYESGDHVAVYPANDSALVNQLGKILGADLDVVMSLNNLDEESNKKHP
FPCPTSYRTALTYYLDITNPPRTNVLYELAQYASEPSEQELLRKMASSSGEGKELYLSWV
VEARRHILAILQDCPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVVVEYET
KAGRINKGVATNWLRAKEPAGENGGRALVPMFVRKSQFRLPFKATTPVIMVGPGTGVAPF
IGFIQERAWLRQQGKEVGETLLYYGCRRSDEDYLYREELAQFHRDGALTQLNVAFSREQS
HKVYVQHLLKQDREHLWKLIEGGAHIYVCGDARNMARDVQNTFYDIVAELGAMEHAQAVD
YIKKLMTKGRYSLDVWS
NT seq 2034 nt   +upstreamnt  +downstreamnt
atgggagactcccacgtggacaccagctccaccgtgtccgaggcggtggccgaagaagta
tctcttttcagcatgacggacatgattctgttttcgctcatcgtgggtctcctaacctac
tggttcctcttcagaaagaaaaaagaagaagtccccgagttcaccaaaattcagacattg
acctcctctgtcagagagagcagctttgtggaaaagatgaagaaaacggggaggaacatc
atcgtgttctacggctcccagacggggactgcagaggagtttgccaaccgcctgtccaag
gacgcccaccgctacgggatgcgaggcatgtcagcggaccctgaggagtatgacctggcc
gacctgagcagcctgccagagatcgacaacgccctggtggttttctgcatggccacctac
ggtgagggagaccccaccgacaatgcccaggacttctacgactggctgcaggagacagac
gtggatctctctggggtcaagttcgcggtgtttggtcttgggaacaagacctacgagcac
ttcaatgccatgggcaagtacgtggacaagcggctggagcagctcggcgcccagcgcatc
tttgagctggggttgggcgacgacgatgggaacttggaggaggacttcatcacctggcga
gagcagttctggccggccgtgtgtgaacactttggggtggaagccactggcgaggagtcc
agcattcgccagtacgagcttgtggtccacaccgacatagatgcggccaaggtgtacatg
ggggagatgggccggctgaagagctacgagaaccagaagcccccctttgatgccaagaat
ccgttcctggctgcagtcaccaccaaccggaagctgaaccagggaaccgagcgccacctc
atgcacctggaattggacatctcggactccaaaatcaggtatgaatctggggaccacgtg
gctgtgtacccagccaacgactctgctctcgtcaaccagctgggcaaaatcctgggtgcc
gacctggacgtcgtcatgtccctgaacaacctggatgaggagtccaacaagaagcaccca
ttcccgtgccctacgtcctaccgcacggccctcacctactacctggacatcaccaacccg
ccgcgtaccaacgtgctgtacgagctggcgcagtacgcctcggagccctcggagcaggag
ctgctgcgcaagatggcctcctcctccggcgagggcaaggagctgtacctgagctgggtg
gtggaggcccggaggcacatcctggccatcctgcaggactgcccgtccctgcggcccccc
atcgaccacctgtgtgagctgctgccgcgcctgcaggcccgctactactccatcgcctca
tcctccaaggtccaccccaactctgtgcacatctgtgcggtggttgtggagtacgagacc
aaggctggccgcatcaacaagggcgtggccaccaactggctgcgggccaaggagcctgcc
ggggagaacggcggccgtgcgctggtgcccatgttcgtgcgcaagtcccagttccgcctg
cccttcaaggccaccacgcctgtcatcatggtgggccccggcaccggggtggcacccttc
ataggcttcatccaggagcgggcctggctgcgacagcagggcaaggaggtgggggagacg
ctgctgtactacggctgccgccgctcggatgaggactacctgtaccgggaggagctggcg
cagttccacagggacggtgcgctcacccagctcaacgtggccttctcccgggagcagtcc
cacaaggtctacgtccagcacctgctaaagcaagaccgagagcacctgtggaagttgatc
gaaggcggtgcccacatctacgtctgtggggatgcacggaacatggccagggatgtgcag
aacaccttctacgacatcgtggctgagctcggggccatggagcacgcgcaggcggtggac
tacatcaagaaactgatgaccaagggccgctactccctggacgtgtggagctag

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Ontology (2)   
   KEGG BRITE (2)   
Disease (7)   
   KEGG DISEASE (3)   
   OMIM (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (8)   
   RefSeq(pep) (8)   
DNA sequence (40)   
   RefSeq(nuc) (8)   
   GenBank (16)   
   EMBL (16)   
Protein domain (3)   
   Pfam (3)   
All databases (80)   

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