KEGG   Homo sapiens (human): 5449
Entry
5449              CDS       T01001                                 
Symbol
POU1F1, CPHD1, GHF-1, PIT1, POU1F1a, Pit-1
Name
(RefSeq) POU class 1 homeobox 1
  KO
K09363  POU domain transcription factor, class 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04935  Growth hormone synthesis, secretion and action
Network
nt06324  GHRH-GH-IGF signaling
  Element
N00910  GHRHR-PKA-GH signaling pathway
Disease
H00254  Growth hormone deficiency
H02036  Combined pituitary hormone deficiency
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    5449 (POU1F1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    5449 (POU1F1)
Transcription factors [BR:hsa03000]
 Eukaryotic type
  Helix-turn-helix
   Homeo domain POU
    5449 (POU1F1)
SSDB
Motif
Pfam: Pou Homeodomain Homeobox_KN Lsr2
Other DBs
NCBI-GeneID: 5449
NCBI-ProteinID: NP_000297
OMIM: 173110
HGNC: 9210
Ensembl: ENSG00000064835
UniProt: P28069
Structure
Position
3:complement(87259404..87276584)
AA seq 291 aa
MSCQAFTSADTFIPLNSDASATLPLIMHHSAAECLPVSNHATNVMSTATGLHYSVPSCHY
GNQPSTYGVMAGSLTPCLYKFPDHTLSHGFPPIHQPLLAEDPTAADFKQELRRKSKLVEE
PIDMDSPEIRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSF
KNACKLKAILSKWLEEAEQVGALYNEKVGANERKRKRRTTISIAAKDALERHFGEQNKPS
SQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKTSLNQSLFSISKEHLECR
NT seq 876 nt   +upstreamnt  +downstreamnt
atgagttgccaagcttttacttcggctgatacctttatacctctgaattctgacgcctct
gcaactctgcctctgataatgcatcacagtgctgccgagtgtctaccagtctccaaccat
gccaccaatgtgatgtctacagcaacaggacttcattattctgttccttcctgtcattat
ggaaaccagccatcaacctatggagtgatggcaggtagtttaaccccttgtctttataaa
tttcctgaccacaccttgagtcatggatttcctcctatacaccagcctcttctggcagag
gaccccacagctgctgatttcaagcaggaactcaggcggaaaagtaaattggtggaagag
ccaatagacatggattctccagaaatcagagaacttgaaaagtttgccaatgaatttaaa
gtgagacgaattaaattaggatacacccagacaaatgttggggaggccctggcagctgtg
catggctctgaattcagtcaaacaacaatctgccgatttgaaaatctgcagctcagcttt
aaaaatgcatgcaaactgaaagcaatattatccaaatggctggaggaagctgagcaagta
ggagctttgtacaatgaaaaagtgggagcaaatgaaaggaaaagaaaacgaagaacaact
ataagcattgctgctaaagatgctctggagagacactttggagaacagaataaaccttct
tctcaagagatcatgaggatggctgaagaactgaatctggagaaagaagtagtaagagtt
tggttttgcaaccggaggcagagagaaaaacgggtgaaaacaagtctgaatcagagttta
ttttctatttctaaggaacatcttgagtgcagataa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (2)   
   KEGG NETWORK (2)   
Disease (4)   
   KEGG DISEASE (2)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (12)   
   RefSeq(nuc) (2)   
   GenBank (5)   
   EMBL (5)   
3D Structure (1)   
   PDB (1)   
Protein domain (4)   
   Pfam (4)   
All databases (38)   

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