KEGG   Homo sapiens (human): 54512
Entry
54512             CDS       T01001                                 
Symbol
EXOSC4, RRP41, RRP41A, Rrp41p, SKI6, Ski6p, hRrp41p, p12A
Name
(RefSeq) exosome component 4
  KO
K11600  exosome complex component RRP41
Organism
hsa  Homo sapiens (human)
Pathway
hsa03018  RNA degradation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03018 RNA degradation
    54512 (EXOSC4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    54512 (EXOSC4)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA degradation factors
   3'-5' decay
    Core exosome factors
     54512 (EXOSC4)
 Prokaryotic type
  Archeal mRNA degradation factors
   Exosome components
    Cofactors
     54512 (EXOSC4)
SSDB
Motif
Pfam: RNase_PH RNase_PH_C
Other DBs
NCBI-GeneID: 54512
NCBI-ProteinID: NP_061910
OMIM: 606491
HGNC: 18189
Ensembl: ENSG00000178896
UniProt: Q9NPD3
Structure
Position
8:144064056..144080648
AA seq 245 aa
MAGLELLSDQGYRVDGRRAGELRKIQARMGVFAQADGSAYIEQGNTKALAVVYGPHEIRG
SRARALPDRALVNCQYSSATFSTGERKRRPHGDRKSCEMGLQLRQTFEAAILTQLHPRSQ
IDIYVQVLQADGGTYAACVNAATLAVLDAGIPMRDFVCACSAGFVDGTALADLSHVEEAA
GGPQLALALLPASGQIALLEMDARLHEDHLERVLEAAAQAARDVHTLLDRVVRQHVREAS
ILLGD
NT seq 738 nt   +upstreamnt  +downstreamnt
atggcggggctggagctcttgtcggaccagggctaccgggtggacgggcggcgcgccggg
gagctgcgcaagatccaggcgcggatgggcgtgttcgcgcaggctgacggctcggcctac
attgagcagggcaacaccaaggcactggctgtggtctacggcccgcacgagatccggggc
tcccgggctcgagccctgccggacagggccctagtgaactgtcaatatagttcagcgacc
ttcagcacaggtgagcgcaagcgacggccacatggggaccgtaagtcctgtgagatgggc
ctgcagctccgccagactttcgaagcagccatcctcacacagctgcacccacgctcccag
attgatatctatgtgcaggtgctacaggcagatggtgggacctatgcagcttgtgtgaat
gcagccacgctggcagtgctggatgccgggatacccatgagagactttgtgtgtgcgtgc
tcagctggcttcgtggacggcacagccctggcggacctcagccatgtggaggaagcagct
ggtggcccccagctggccctggccctgctgccagcctcaggacagattgcgctgcttgag
atggatgcccggctgcacgaggaccacctggagcgggtgttggaggctgctgcccaggct
gcccgagatgtgcacaccctcttagatcgagtggtccggcagcatgtgcgtgaggcctct
atcttgctgggggactga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (6)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (10)   
   RefSeq(nuc) (2)   
   GenBank (4)   
   EMBL (4)   
3D Structure (4)   
   PDB (4)   
Protein domain (2)   
   Pfam (2)   
All databases (40)   

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