KEGG   Homo sapiens (human): 54577
Entry
54577             CDS       T01001                                 
Symbol
UGT1A7, GNT1, UDPGT, UDPGT_1-7, UGT-1A, UGT-1G, UGT1, UGT1-01, UGT1-07, UGT1.1, UGT1.7, UGT1A, UGT1A1, UGT1G, hUG-BR1
Name
(RefSeq) UDP glucuronosyltransferase family 1 member A7
  KO
K00699  glucuronosyltransferase [EC:2.4.1.17]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00040  Pentose and glucuronate interconversions
hsa00053  Ascorbate and aldarate metabolism
hsa00140  Steroid hormone biosynthesis
hsa00830  Retinol metabolism
hsa00860  Porphyrin metabolism
hsa00980  Metabolism of xenobiotics by cytochrome P450
hsa00982  Drug metabolism - cytochrome P450
hsa00983  Drug metabolism - other enzymes
hsa01100  Metabolic pathways
hsa01240  Biosynthesis of cofactors
hsa04976  Bile secretion
hsa05204  Chemical carcinogenesis - DNA adducts
hsa05207  Chemical carcinogenesis - receptor activation
Module
hsa_M00014  Glucuronate pathway (uronate pathway)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00040 Pentose and glucuronate interconversions
    54577 (UGT1A7)
   00053 Ascorbate and aldarate metabolism
    54577 (UGT1A7)
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    54577 (UGT1A7)
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    54577 (UGT1A7)
   00860 Porphyrin metabolism
    54577 (UGT1A7)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    54577 (UGT1A7)
   00982 Drug metabolism - cytochrome P450
    54577 (UGT1A7)
   00983 Drug metabolism - other enzymes
    54577 (UGT1A7)
 09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    54577 (UGT1A7)
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    54577 (UGT1A7)
   05207 Chemical carcinogenesis - receptor activation
    54577 (UGT1A7)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases [BR:hsa01003]
    54577 (UGT1A7)
Enzymes [BR:hsa01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.17  glucuronosyltransferase
     54577 (UGT1A7)
Glycosyltransferases [BR:hsa01003]
 Others
  Hydrophobic molecule
   54577 (UGT1A7)
SSDB
Motif
Pfam: UDPGT EryCIII-like_C Glyco_tran_28_C
Other DBs
NCBI-GeneID: 54577
NCBI-ProteinID: NP_061950
OMIM: 606432
HGNC: 12539
Ensembl: ENSG00000244122
UniProt: Q9HAW7 Q5DSZ7
Position
2:233681901..233773300
AA seq 530 aa
MARAGWTGLLPLYVCLLLTCGFAKAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVVVVMP
EVSWQLGRSLNCTVKTYSTSYTLEDQDREFMVFADARWTAPLRSAFSLLTSSSNGIFDLF
FSNCRSLFNDRKLVEYLKESCFDAVFLDPFDACGLIVAKYFSLPSVVFARGIFCHYLEEG
AQCPAPLSYVPRLLLGFSDAMTFKERVWNHIMHLEEHLFCPYFFKNVLEIASEILQTPVT
AYDLYSHTSIWLLRTDFVLEYPKPVMPNMIFIGGINCHQGKPVPMEFEAYINASGEHGIV
VFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGH
PMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDL
ENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTW
YQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
NT seq 1593 nt   +upstreamnt  +downstreamnt
atggctcgtgcagggtggactggcctccttcccctatatgtgtgtctactgctgacctgt
ggctttgccaaggcagggaagctgctggtagtgcccatggatgggagccactggttcacc
atgcagtcggtggtggagaaactcatcctcagggggcatgaggtggtcgtagtcatgcca
gaggtgagttggcaactgggaagatcactgaattgcacagtgaagacttactcaacctca
tacactctggaggatcaggaccgggagttcatggtttttgccgatgctcgctggacggca
ccattgcgaagtgcattttctctattaacaagttcatccaatggtatttttgacttattt
ttttcaaattgcaggagtttgtttaatgaccgaaaattagtagaatacttaaaggagagt
tgttttgatgcagtgtttctcgatccttttgatgcctgtggcttaattgttgccaaatat
ttctccctcccctctgtggtcttcgccaggggaatattttgccactatcttgaagaaggt
gcacagtgccctgctcctctttcctatgtccccagacttctcttagggttctcagacgcc
atgactttcaaggagagagtatggaaccacatcatgcacttggaggaacatttattttgc
ccctattttttcaaaaatgtcttagaaatagcctctgaaattctccaaacccctgtcacg
gcatatgatctctacagccacacatcaatttggttgttgcgaactgactttgttttggag
tatcccaaacccgtgatgcccaatatgatcttcattggtggtatcaactgtcatcaggga
aagccagtgcctatggaatttgaagcctacattaatgcttctggagaacatggaattgtg
gttttctctttgggatcaatggtctcagaaattccagagaagaaagctatggcaattgct
gatgctttgggcaaaatccctcagacagtcctgtggcggtacactggaacccgaccatcg
aatcttgcgaacaacacgatacttgttaagtggctaccccaaaacgatctgcttggtcac
ccgatgacccgtgcctttatcacccatgctggttcccatggtgtttatgaaagcatatgc
aatggcgttcccatggtgatgatgcccttgtttggtgatcagatggacaatgcaaagcgc
atggagactaagggagctggagtgaccctgaatgttctggaaatgacttctgaagattta
gaaaatgctctaaaagcagtcatcaatgacaaaagttacaaggagaacatcatgcgcctc
tccagccttcacaaggaccgcccggtggagccgctggacctggccgtgttctgggtggag
tttgtgatgaggcacaagggcgcgccacacctgcgccccgcagcccacgacctcacctgg
taccagtaccattccttggacgtgattggtttcctcttggccgtcgtgctgacagtggcc
ttcatcacctttaaatgttgtgcttatggctaccggaaatgcttggggaaaaaagggcga
gttaagaaagcccacaaatccaagacccattga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (15)   
   KEGG PATHWAY (13)   
   KEGG MODULE (2)   
Disease (1)   
   OMIM (1)   
Chemical substance (40)   
   KEGG COMPOUND (40)   
Chemical reaction (21)   
   KEGG ENZYME (1)   
   KEGG REACTION (20)   
Genome (1)   
   KEGG GENOME (1)   
Gene (26)   
   KEGG ORTHOLOGY (1)   
   RefGene (20)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (9)   
   RefSeq(nuc) (1)   
   GenBank (4)   
   EMBL (4)   
Protein domain (3)   
   Pfam (3)   
All databases (123)   

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