KEGG   Homo sapiens (human): 54890
Entry
54890             CDS       T01001                                 
Symbol
ALKBH5, ABH5, OFOXD, OFOXD1
Name
(RefSeq) alkB homolog 5, RNA demethylase
  KO
K10767  mRNA N6-methyladenine demethylase [EC:1.14.11.53]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    54890 (ALKBH5)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.11  With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
    1.14.11.53  mRNA N6-methyladenine demethylase
     54890 (ALKBH5)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA processing factors
   3' end processing
    Negative regulators of mRNA 3' end processing
     54890 (ALKBH5)
SSDB
Motif
Pfam: 2OG-FeII_Oxy_2 PI3K_1B_p101 Selenoprotein_S
Other DBs
NCBI-GeneID: 54890
NCBI-ProteinID: NP_060228
OMIM: 613303
HGNC: 25996
Ensembl: ENSG00000091542
UniProt: Q6P6C2
Structure
Position
17:18183828..18209954
AA seq 394 aa
MAAASGYTDLREKLKSMTSRDNYKAGSREAAAAAAAAVAAAAAAAAAAEPYPVSGAKRKY
QEDSDPERSDYEEQQLQKEEEARKVKSGIRQMRLFSQDECAKIEARIDEVVSRAEKGLYN
EHTVDRAPLRNKYFFGEGYTYGAQLQKRGPGQERLYPPGDVDEIPEWVHQLVIQKLVEHR
VIPEGFVNSAVINDYQPGGCIVSHVDPIHIFERPIVSVSFFSDSALCFGCKFQFKPIRVS
EPVLSLPVRRGSVTVLSGYAADEITHCIRPQDIKERRAVIILRKTRLDAPRLETKSLSSS
VLPPSYASDRLSGNNRDPALKPKRSHRKADPDAAHRPRILEMDKEENRRSVLLPTHRRRG
SFSSENYWRKSYESSEDCSEAAGSPARKVKMRRH
NT seq 1185 nt   +upstreamnt  +downstreamnt
atggcggccgccagcggctacacggacctgcgtgagaagctcaagtccatgacgtcccgg
gacaactataaggcgggcagccgggaggccgccgccgctgccgcagccgccgtagccgcc
gcagccgcagccgccgctgccgccgaaccttaccctgtgtccggggccaagcgcaagtat
caggaggactcggaccccgagcgcagcgactatgaggagcagcagctgcagaaggaggag
gaggcgcgcaaggtgaagagcggcatccgccagatgcgcctcttcagccaggacgagtgc
gccaagatcgaggcccgcattgacgaggtggtgtcccgcgctgagaagggcctgtacaac
gagcacacggtggaccgggccccactgcgcaacaagtacttcttcggcgaaggctacact
tacggcgcccagctgcagaagcgcgggcccggccaggagcgcctctacccgccgggcgac
gtggacgagatccccgagtgggtgcaccagctggtgatccaaaagctggtggagcaccgc
gtcatccccgagggcttcgtcaacagcgccgtcatcaacgactaccagcccggcggctgc
atcgtgtctcacgtggaccccatccacatcttcgagcgccccatcgtgtccgtgtccttc
tttagcgactctgcgctgtgcttcggctgcaagttccagttcaagcctattcgggtgtcg
gaaccagtgctttccctgccggtgcgcaggggaagcgtgactgtgctcagtggatatgct
gctgatgaaatcactcactgcatacggcctcaggacatcaaggagcgccgagcagtcatc
atcctcaggaagacaagattagatgcaccccggttggaaacaaagtccctgagcagctcc
gtgttaccacccagctatgcttcagatcgcctgtcaggaaacaacagggaccctgctctg
aaacccaagcggtcccaccgcaaggcagaccctgatgctgcccacaggccacggatcctg
gagatggacaaggaagagaaccggcgctcggtgctgctgcccacacaccggcggaggggt
agcttcagctctgagaactactggcgcaagtcatacgagtcctcagaggactgctctgag
gcagcaggcagccctgcccgaaaggtgaagatgcggcggcactga

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Ontology (3)   
   KEGG BRITE (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (21)   
   RefSeq(nuc) (1)   
   GenBank (10)   
   EMBL (10)   
3D Structure (11)   
   PDB (11)   
Protein domain (3)   
   Pfam (3)   
All databases (59)   

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