KEGG   Homo sapiens (human): 54973
Entry
54973             CDS       T01001                                 
Symbol
INTS11, CPSF3L, CPSF73L, INT11, NEDMLOB, PSF3L, RC-68, RC68
Name
(RefSeq) integrator complex subunit 11
  KO
K13148  integrator complex subunit 11 [EC:3.1.27.-]
Organism
hsa  Homo sapiens (human)
Disease
H02470  Neurodevelopmental disorder with structural brain abnormalities
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03041 Spliceosome [BR:hsa03041]
    54973 (INTS11)
Spliceosome [BR:hsa03041]
 Other splicing related proteins
  Proteins involved in snRNP biogenesis
   Integrator complex
    54973 (INTS11)
SSDB
Motif
Pfam: IntS11_C Beta-Casp Lactamase_B_6 RMMBL Lactamase_B Lactamase_B_2 Beta_lactamase3 Lactamase_B_3
Other DBs
NCBI-GeneID: 54973
NCBI-ProteinID: NP_060341
OMIM: 611354
HGNC: 26052
Ensembl: ENSG00000127054
UniProt: Q5TA45
Structure
Position
1:complement(1311600..1324660)
AA seq 600 aa
MPEIRVTPLGAGQDVGRSCILVSIAGKNVMLDCGMHMGFNDDRRFPDFSYITQNGRLTDF
LDCVIISHFHLDHCGALPYFSEMVGYDGPIYMTHPTQAICPILLEDYRKIAVDKKGEANF
FTSQMIKDCMKKVVAVHLHQTVQVDDELEIKAYYAGHVLGAAMFQIKVGSESVVYTGDYN
MTPDRHLGAAWIDKCRPNLLITESTYATTIRDSKRCRERDFLKKVHETVERGGKVLIPVF
ALGRAQELCILLETFWERMNLKVPIYFSTGLTEKANHYYKLFIPWTNQKIRKTFVQRNMF
EFKHIKAFDRAFADNPGPMVVFATPGMLHAGQSLQIFRKWAGNEKNMVIMPGYCVQGTVG
HKILSGQRKLEMEGRQVLEVKMQVEYMSFSAHADAKGIMQLVGQAEPESVLLVHGEAKKM
EFLKQKIEQELRVNCYMPANGETVTLPTSPSIPVGISLGLLKREMAQGLLPEAKKPRLLH
GTLIMKDSNFRLVSSEQALKELGLAEHQLRFTCRVHLHDTRKEQETALRVYSHLKSVLKD
HCVQHLPDGSVTVESVLLQAAAPSEDPGTKVLLVSWTYQDEELGSFLTSLLKKGLPQAPS
NT seq 1803 nt   +upstreamnt  +downstreamnt
atgcctgagatcagagtcacgcccttgggggccggccaggacgtgggccgaagctgcatc
ctggtctccattgcgggcaagaatgtcatgctggactgtggaatgcacatgggcttcaat
gacgaccgacgcttccctgacttctcctacatcacccagaacggccgcctaacagacttc
ctggactgtgtgatcattagccacttccacctggaccactgcggggcactcccctacttc
agcgagatggtgggctacgacgggcccatctacatgactcaccccacccaggccatctgc
cccatcttgctggaggactaccgcaagatcgccgtagacaagaagggcgaggccaacttc
ttcacctcccagatgatcaaagactgcatgaagaaggtggtggctgtccacctccaccag
acggtccaggtagatgatgagctggagatcaaggcctactatgcaggccacgtgctgggg
gcagccatgttccagattaaagtgggctcagagtctgtggtctacacgggtgattataac
atgaccccagaccgacacttaggagctgcctggattgacaagtgccgccccaacctgctc
atcacagagtccacgtacgccacgaccatccgtgactccaagcgctgccgggagcgagac
ttcctgaagaaagtccacgagaccgtggagcgtggtgggaaggtgctgatacctgtgttc
gcgctgggccgcgcccaggagctctgcatcctcctggagaccttctgggagcgcatgaac
ctgaaggtgcccatctacttctccacggggctgaccgagaaggccaaccactactacaag
ctgttcatcccctggaccaaccagaagatccgcaagactttcgtgcagaggaacatgttt
gagttcaagcacatcaaggccttcgaccgggcttttgctgacaacccaggaccgatggtt
gtgtttgccacgccaggaatgctgcacgctgggcagtccctgcagatcttccggaaatgg
gccggaaacgaaaagaacatggtcatcatgcccggctactgcgtgcagggcaccgtcggc
cacaagatcctcagcgggcagcggaagctcgagatggaggggcggcaggtgctggaggtc
aagatgcaggtggagtacatgtcattcagcgcacacgcggacgccaagggcatcatgcag
ctggtgggccaggcagagccggagagcgtgctgctggtgcatggcgaggccaagaagatg
gagttcctgaagcagaagatcgagcaggagctccgggtcaactgctacatgccggccaat
ggcgagacggtgacgctgcccacaagccccagcatccccgtaggcatctcgctggggctg
ctgaagcgggagatggcgcaggggctgctccctgaggccaagaagcctcggctcctgcac
ggcaccctgatcatgaaggacagcaacttccggctggtgtcctcagagcaagccctcaaa
gagctgggtctggctgagcaccagctgcgcttcacctgccgcgtgcacctgcatgacaca
cgcaaggagcaggagacggcattgcgcgtctacagccacctcaagagcgtcctgaaggac
cactgtgtgcagcacctcccagacggctctgtgactgtggagtccgtcctcctccaggcc
gccgccccttctgaggacccaggcaccaaggtgctgctggtctcctggacctaccaggac
gaggagctggggagcttcctcacatctctgctgaagaagggcctcccccaggcccccagc
tga

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Ontology (2)   
   KEGG BRITE (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (8)   
   OC (1)   
Protein sequence (13)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (11)   
DNA sequence (66)   
   RefSeq(nuc) (12)   
   GenBank (27)   
   EMBL (27)   
3D Structure (6)   
   PDB (6)   
Protein domain (8)   
   Pfam (8)   
All databases (119)   

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