KEGG   Homo sapiens (human): 55072
Entry
55072             CDS       T01001                                 
Symbol
RNF31, HOIP, IMD115, Paul, ZIBRA
Name
(RefSeq) ring finger protein 31
  KO
K11974  E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04217  Necroptosis
hsa04621  NOD-like receptor signaling pathway
hsa05131  Shigellosis
Network
nt06182  Shigella
nt06516  TNF signaling
  Element
N00945  Shigella IpaH1.4/2.5 to TNF-NFKB signaling pathway
N01545  Regulation of TNF-NFKB signaling pathway, LUBAC-mediated linear ubiquitination
Disease
H02525  Disorders of innate immunity
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    55072 (RNF31)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    55072 (RNF31)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05131 Shigellosis
    55072 (RNF31)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    55072 (RNF31)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.31  RBR-type E3 ubiquitin transferase
     55072 (RNF31)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   RBR proteins
    55072 (RNF31)
  Multi subunit Ring-finger type E3
   LUBAC complex
    55072 (RNF31)
SSDB
Motif
Pfam: HOIP-UBA PUB_1 E3_UbLigase_RBR PUB IBR zf-RanBP UBA
Other DBs
NCBI-GeneID: 55072
NCBI-ProteinID: NP_060469
OMIM: 612487
HGNC: 16031
Ensembl: ENSG00000092098
UniProt: Q96EP0
Structure
Position
14:24146875..24160655
AA seq 1072 aa
MPGEEEERAFLVAREELASALRRDSGQAFSLEQLRPLLASSLPLAARYLQLDAARLVRCN
AHGEPRNYLNTLSTALNILEKYGRNLLSPQRPRYWRGVKFNNPVFRSTVDAVQGGRDVLR
LYGYTEEQPDGLSFPEGQEEPDEHQVATVTLEVLLLRTELSLLLQNTHPRQQALEQLLED
KVEDDMLQLSEFDPLLREIAPGPLTTPSVPGSTPGPCFLCGSAPGTLHCPSCKQALCPAC
DHLFHGHPSRAHHLRQTLPGVLQGTHLSPSLPASAQPRPQSTSLLALGDSSLSSPNPASA
HLPWHCAACAMLNEPWAVLCVACDRPRGCKGLGLGTEGPQGTGGLEPDLARGRWACQSCT
FENEAAAVLCSICERPRLAQPPSLVVDSRDAGICLQPLQQGDALLASAQSQVWYCIHCTF
CNSSPGWVCVMCNRTSSPIPAQHAPRPYASSLEKGPPKPGPPRRLSAPLPSSCGDPEKQR
QDKMREEGLQLVSMIREGEAAGACPEEIFSALQYSGTEVPLQWLRSELPYVLEMVAELAG
QQDPGLGAFSCQEARRAWLDRHGNLDEAVEECVRTRRRKVQELQSLGFGPEEGSLQALFQ
HGGDVSRALTELQRQRLEPFRQRLWDSGPEPTPSWDGPDKQSLVRRLLAVYALPSWGRAE
LALSLLQETPRNYELGDVVEAVRHSQDRAFLRRLLAQECAVCGWALPHNRMQALTSCECT
ICPDCFRQHFTIALKEKHITDMVCPACGRPDLTDDTQLLSYFSTLDIQLRESLEPDAYAL
FHKKLTEGVLMRDPKFLWCAQCSFGFIYEREQLEATCPQCHQTFCVRCKRQWEEQHRGRS
CEDFQNWKRMNDPEYQAQGLAMYLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSG
CYNAFYAKNKCPEPNCRVKKSLHGHHPRDCLFYLRDWTALRLQKLLQDNNVMFNTEPPAG
ARAVPGGGCRVIEQKEVPNGLRDEACGKETPAGYAGLCQAHYKEYLVSLINAHSLDPATL
YEVEELETATERYLHVRPQPLAGEDPPAYQARLLQKLTEEVPLGQSIPRRRK
NT seq 3219 nt   +upstreamnt  +downstreamnt
atgccgggggaggaagaggagcgggccttcctggtggcccgcgaggagctggcgagcgcc
ctgaggagggattccgggcaggcgttttccctggagcagctccggccgctactagccagc
tctctgccgctagccgcccgctacctgcagctggacgccgcacgccttgtccgctgcaac
gctcatggggagccccgaaactacctcaacaccctgtccacggctctgaacatcctggag
aaatacggccgcaaccttctcagccctcagcggcctcggtactggcgtggtgtcaagttt
aataaccctgtctttcgcagcacggtggatgctgtgcaggggggccgagatgtgctgcga
ttatatggctacacagaggagcaaccagatgggttgagcttccccgaagggcaggaggag
ccagatgagcaccaggttgctacagtcacactggaagtactgctgcttcggacagagctc
agcctgctattgcagaatactcatccaagacagcaggcactggagcagctgttggaagac
aaggttgaagatgatatgctgcagctttcagaatttgaccccctattgagagagattgct
cctggccccctcaccacaccctctgtcccaggctccactcctggtccctgcttcctctgt
ggttctgccccaggcacactgcactgcccatcctgtaaacaggccctgtgtccagcctgt
gaccacctgttccatggacacccatcccgtgctcatcacctccgccagaccctgcctggg
gtcctgcagggtacccacctgagccccagtttacctgcctcagcccaaccacggccccag
tcgacctccctgctggccctgggagacagctctctttcttcccctaatcctgcaagtgct
catttgccctggcactgtgctgcctgtgccatgctaaatgagccttgggcagtgctctgt
gtggcctgtgatcggccccgaggctgtaaggggttggggttgggaactgagggtccccaa
ggaactggaggcctagaacctgatcttgcacggggtcggtgggcctgccagagctgtacc
tttgagaatgaggcagctgctgtgctatgttccatatgtgagcgacctcggctggcccag
cctcccagcttggtggtggattcccgagatgctggcatttgcctgcaaccccttcagcag
ggggatgctttgctggcctctgcccagagtcaagtctggtactgtattcactgtaccttc
tgcaactcgagccctggctgggtgtgtgttatgtgcaaccggactagtagccccattcca
gcacaacatgccccccggccctatgccagctctttggaaaagggaccccccaagcctggg
cccccacgacgccttagtgcccccctgcccagttcctgtggagatcctgagaagcagcgc
caagacaagatgcgggaagaaggcctccagctagtgagcatgatccgggaaggggaagcc
gcaggtgcctgtccagaggagatcttctcggctctgcagtactcgggcactgaggtgcct
ctgcagtggttgcgctcagaactgccctacgtcctggagatggtggctgagctggctgga
cagcaggaccctgggctgggtgccttttcctgtcaggaggcccggagagcctggctggat
cgtcatggcaaccttgatgaagctgtggaggagtgtgtgaggaccaggcgaaggaaggtg
caggagctccagtctctaggctttgggcctgaggaggggtctctccaggcattgttccag
cacggaggtgatgtgtcacgggccctgactgagctacagcgccaacgcctagagcccttc
cgccagcgcctctgggacagtggccctgagcccaccccttcctgggatgggccagacaag
cagagcctggtcaggcggcttttggcagtctacgcactccccagctggggccgggcagag
ctggcactgtcactgctgcaggagacacccaggaactatgagttgggggatgtggtagaa
gctgtgaggcacagccaggaccgggccttcctgcgccgcttgcttgcccaggagtgtgcc
gtgtgtggctgggccctgccccacaaccggatgcaggccctgacttcctgtgagtgcacc
atctgtcctgactgcttccgccagcacttcaccatcgccttgaaggagaagcacatcaca
gacatggtgtgccctgcctgtggccgccccgacctcaccgatgacacacagttgctcagc
tacttctctacccttgacatccagcttcgcgagagcctagagccagatgcctatgcgttg
ttccataagaagctgaccgagggtgtgctgatgcgggaccccaagttcttgtggtgtgcc
cagtgctcctttggcttcatatatgagcgtgagcagctggaggcaacttgtccccagtgt
caccagaccttctgtgtgcgctgcaagcgccagtgggaggagcagcaccgaggtcggagc
tgtgaggacttccagaactggaaacgcatgaacgacccagaataccaggcccagggccta
gcaatgtatcttcaggaaaacggcattgactgccccaaatgcaagttctcgtacgccctg
gcccgaggaggctgcatgcactttcactgtacccagtgccgccaccagttctgcagcggc
tgctacaatgccttttacgccaagaataaatgtccagagcctaactgcagggtgaaaaag
tccctgcacggccaccaccctcgagactgcctcttctacctgcgggactggactgctctc
cggcttcagaagctgctacaggacaataacgtcatgtttaatacagagcctccagctggg
gcccgggcagtccctggaggcggctgccgagtgatagagcagaaggaggttcccaatggg
ctcagggacgaagcttgtggcaaggaaactccagctggctatgccggcctgtgccaggca
cactacaaagagtatcttgtgagcctcatcaatgcccactcgctggacccagccaccttg
tatgaggtggaagagctggagacggccactgagcgctacctgcacgtacgcccccagcct
ttggctggagaggatccccctgcttaccaggcccgcttgttacagaagctgacagaagag
gtacccttgggacagagtatcccccgcaggcggaagtag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Network (4)   
   KEGG NETWORK (4)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (54)   
   KEGG ORTHOLOGY (1)   
   RefGene (44)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (34)   
   RefSeq(nuc) (2)   
   GenBank (16)   
   EMBL (16)   
3D Structure (29)   
   PDB (29)   
Protein domain (7)   
   Pfam (7)   
All databases (143)   

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