KEGG   Homo sapiens (human): 55159
Entry
55159             CDS       T01001                                 
Symbol
RFWD3, FANCW, RNF201
Name
(RefSeq) ring finger and WD repeat domain 3
  KO
K15691  E3 ubiquitin-protein ligase RFWD3 [EC:2.3.2.27]
Organism
hsa  Homo sapiens (human)
Network
nt06508  Interstrand crosslink repair
  Element
N01539  RAD51 -dsDNA destabilization
Disease
H00238  Fanconi anemia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    55159 (RFWD3)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     55159 (RFWD3)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   Other single Ring-finger type E3
    55159 (RFWD3)
SSDB
Motif
Pfam: zf-RING_2 zf-C3HC4 zf-RING_UBOX zf-C3HC4_2 WD40 zf-RING_5 zf-rbx1 zf-RING_11 Rtf2 zf-C3HC4_4 Nairovirus_Gn WD40_2 zf-ANAPC11 zf-UDP NBCH_WD40
Other DBs
NCBI-GeneID: 55159
NCBI-ProteinID: NP_060594
OMIM: 614151
HGNC: 25539
Ensembl: ENSG00000168411
UniProt: Q6PCD5
Structure
Position
16:complement(74621399..74666877)
AA seq 774 aa
MAHEAMEYDVQVQLNHAEQQPAPAGMASSQGGPALLQPVPADVVSSQGVPSILQPAPAEV
ISSQATPPLLQPAPQLSVDLTEVEVLGEDTVENINPRTSEQHRQGSDGNHTIPASSLHSM
TNFISGLQRLHGMLEFLRPSSSNHSVGPMRTRRRVSASRRARAGGSQRTDSARLRAPLDA
YFQVSRTQPDLPATTYDSETRNPVSEELQVSSSSDSDSDSSAEYGGVVDQAEESGAVILE
EQLAGVSAEQEVTCIDGGKTLPKQPSPQKSEPLLPSASMDEEEGDTCTICLEQWTNAGDH
RLSALRCGHLFGYRCISTWLKGQVRKCPQCNKKARHSDIVVLYARTLRALDTSEQERMKS
SLLKEQMLRKQAELESAQCRLQLQVLTDKCTRLQRRVQDLQKLTSHQSQNLQQPRGSQAW
VLSCSPSSQGQHKHKYHFQKTFTVSQAGNCRIMAYCDALSCLVISQPSPQASFLPGFGVK
MLSTANMKSSQYIPMHGKQIRGLAFSSYLRGLLLSASLDNTIKLTSLETNTVVQTYNAGR
PVWSCCWCLDEANYIYAGLANGSILVYDVRNTSSHVQELVAQKARCPLVSLSYMPRAASA
AFPYGGVLAGTLEDASFWEQKMDFSHWPHVLPLEPGGCIDFQTENSSRHCLVTYRPDKNH
TTIRSVLMEMSYRLDDTGNPICSCQPVHTFFGGPTCKLLTKNAIFQSPENDGNILVCTGD
EAANSALLWDAASGSLLQDLQTDQPVLDICPFEVNRNSYLATLTEKMVHIYKWE
NT seq 2325 nt   +upstreamnt  +downstreamnt
atggctcatgaagcaatggaatatgatgttcaggtgcagttaaatcatgccgaacaacag
ccagctcctgctggcatggccagcagccaagggggaccagccctcctccagcctgttcct
gctgatgtggtcagcagccagggggtaccatccatcctccagccagctcctgctgaggtg
atcagcagccaagcgacaccacccctgctccagcctgctccgcaactgtctgttgacctg
acagaagtggaggtcttgggagaagacactgtggagaacatcaatccaagaacttcagaa
caacataggcagggatctgatggtaatcacaccatcccagcatcttcgttgcattcaatg
accaacttcatcagcggactgcagagacttcatggcatgctggaattcctgagaccttca
tcttcaaaccacagtgtagggccaatgagaacaagaaggagggtatctgcttcacggagg
gcaagagccggagggtctcagaggacagacagtgccaggttgagagcaccattggatgct
tactttcaggtgagcaggacccagcctgacttgccagctaccacttatgattcagagact
aggaatcctgtatctgaagagttgcaggtgtctagtagttctgattctgacagtgacagc
tctgcagagtatggaggggttgttgaccaggcagaggaatctggagctgtcattttagaa
gagcaactagcaggtgtctcagcagagcaagaagttacatgtatcgatggaggcaagacc
ctccccaaacagccatctccccagaagtctgagcctctgctaccttctgcttctatggat
gaggaagaaggggacacttgtacaatatgtctggaacagtggaccaatgctggggaccac
cggctctcagcattacgctgtgggcatctctttgggtataggtgcatttccacgtggctt
aaaggacaagtacgaaaatgtccccagtgcaacaagaaagccaggcacagtgacattgtc
gtcctttatgcccgaaccctgagagctttggacactagtgaacaggagcgcatgaaaagt
tccctactgaaggaacagatgctaaggaaacaggccgagttagaatcagcacagtgccga
ctccaactgcaggtcctcactgataagtgcactaggcttcaaaggcgtgttcaggacttg
caaaaacttacgtcacatcaaagtcagaatttacagcaacccaggggctcccaagcatgg
gtcctgagctgctcaccctccagccagggccagcacaagcacaagtaccacttccaaaag
accttcacagtatctcaggcaggaaactgccggatcatggcatactgtgatgctctgagc
tgcctggtgatatcacagccttctcctcaggcctcttttcttccaggctttggtgttaag
atgttgagtactgccaacatgaagagcagtcagtacattccgatgcatggcaaacagatc
cgtggactggcgtttagcagttacctcagaggcttgctactctctgcttccctagacaac
actattaaactgaccagcctggagacaaataccgtggtccagacttataatgctggacgt
cctgtctggagctgttgctggtgtcttgatgaggctaactacatctatgctggactggcc
aatggttcaattctggtatatgacgtgcgaaacacgagcagtcatgtgcaggagttagta
gctcagaaagccagatgcccactggtctccctgtcatacatgcccagagctgcctcagct
gcatttccatatggtggggtgctggctggaaccttggaggatgcttcattctgggaacag
aaaatggacttttctcattggcctcatgtgctgcccttggagccagggggctgcatagac
tttcagacagagaacagctcccggcactgtcttgtgacctacaggcctgataaaaatcac
accaccatacgaagtgtgctgatggaaatgtcctaccgactggatgacactggaaatcca
atctgctcctgccagcctgtacatacattttttggaggacctacttgcaaactattgacc
aaaaatgccattttccaaagcccagagaatgatggcaacatcctggtgtgtactggggat
gaagcagcaaattctgccctgctgtgggatgctgccagtggctcgttgctccaggaccta
cagaccgatcagcctgtgttggacatctgcccatttgaggtgaaccgtaacagctacttg
gctaccttaacagagaagatggtccacatctataagtgggagtga

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Ontology (3)   
   KEGG BRITE (3)   
Network (2)   
   KEGG NETWORK (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (23)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (21)   
DNA sequence (39)   
   RefSeq(nuc) (21)   
   GenBank (9)   
   EMBL (9)   
3D Structure (1)   
   PDB (1)   
Protein domain (15)   
   Pfam (15)   
All databases (108)   

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