KEGG   Homo sapiens (human): 55236
Entry
55236             CDS       T01001                                 
Symbol
UBA6, E1-L2, MOP-4, UBE1L2
Name
(RefSeq) ubiquitin like modifier activating enzyme 6
  KO
K10699  ubiquitin-activating enzyme E1-like protein 2 [EC:6.2.1.45]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04120  Ubiquitin mediated proteolysis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    55236 (UBA6)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    55236 (UBA6)
Enzymes [BR:hsa01000]
 6. Ligases
  6.2  Forming carbon-sulfur bonds
   6.2.1  Acid-thiol ligases
    6.2.1.45  E1 ubiquitin-activating enzyme
     55236 (UBA6)
Ubiquitin system [BR:hsa04121]
 Ubiquitin-activating enzymes (E1)
  UBL-activating enzymes
   55236 (UBA6)
SSDB
Motif
Pfam: UBA_E1_SCCH ThiF E1_FCCH E1_4HB E1_UFD Shikimate_DH
Other DBs
NCBI-GeneID: 55236
NCBI-ProteinID: NP_060697
OMIM: 611361
HGNC: 25581
Ensembl: ENSG00000033178
UniProt: A0AVT1
Structure
Position
4:complement(67612652..67701155)
AA seq 1052 aa
MEGSEPVAAHQGEEASCSSWGTGSTNKNLPIMSTASVEIDDALYSRQRYVLGDTAMQKMA
KSHVFLSGMGGLGLEIAKNLVLAGIKAVTIHDTEKCQAWDLGTNFFLSEDDVVNKRNRAE
AVLKHIAELNPYVHVTSSSVPFNETTDLSFLDKYQCVVLTEMKLPLQKKINDFCRSQCPP
IKFISADVHGIWSRLFCDFGDEFEVLDTTGEEPKEIFISNITQANPGIVTCLENHPHKLE
TGQFLTFREINGMTGLNGSIQQITVISPFSFSIGDTTELEPYLHGGIAVQVKTPKTVFFE
SLERQLKHPKCLIVDFSNPEAPLEIHTAMLALDQFQEKYSRKPNVGCQQDSEELLKLATS
ISETLEEKPDVNADIVHWLSWTAQGFLSPLAAAVGGVASQEVLKAVTGKFSPLCQWLYLE
AADIVESLGKPECEEFLPRGDRYDALRACIGDTLCQKLQNLNIFLVGCGAIGCEMLKNFA
LLGVGTSKEKGMITVTDPDLIEKSNLNRQFLFRPHHIQKPKSYTAADATLKINSQIKIDA
HLNKVCPTTETIYNDEFYTKQDVIITALDNVEARRYVDSRCLANLRPLLDSGTMGTKGHT
EVIVPHLTESYNSHRDPPEEEIPFCTLKSFPAAIEHTIQWARDKFESSFSHKPSLFNKFW
QTYSSAEEVLQKIQSGHSLEGCFQVIKLLSRRPRNWSQCVELARLKFEKYFNHKALQLLH
CFPLDIRLKDGSLFWQSPKRPPSPIKFDLNEPLHLSFLQNAAKLYATVYCIPFAEEDLSA
DALLNILSEVKIQEFKPSNKVVQTDETARKPDHVPISSEDERNAIFQLEKAILSNEATKS
DLQMAVLSFEKDDDHNGHIDFITAASNLRAKMYSIEPADRFKTKRIAGKIIPAIATTTAT
VSGLVALEMIKVTGGYPFEAYKNCFLNLAIPIVVFTETTEVRKTKIRNGISFTIWDRWTV
HGKEDFTLLDFINAVKEKYGIEPTMVVQGVKMLYVPVMPGHAKRLKLTMHKLVKPTTEKK
YVDLTVSFAPDIDGDEDLPGPPVRYYFSHDTD
NT seq 3159 nt   +upstreamnt  +downstreamnt
atggaaggatccgagcctgtggccgcccatcagggggaagaggcgtcctgttcttcctgg
gggactggcagcacaaataaaaatttgcccattatgtcaacagcatctgtggaaatcgat
gatgcattgtatagtcgacagaggtacgttcttggagacacagcaatgcagaagatggcc
aagtcccatgttttcttaagtgggatgggtggtcttggtttggaaattgcaaagaatctt
gttcttgcagggattaaggcagttacaattcatgatacagaaaaatgccaagcatgggat
ctaggaaccaacttctttctcagtgaagatgatgttgttaataagagaaacagggctgaa
gctgtacttaaacatattgcagaactaaatccatacgttcatgtcacatcatcttctgtt
cctttcaatgagaccacagatctctcctttttagataaataccagtgtgtagtattgact
gagatgaaacttccattgcagaagaagatcaatgacttttgccgttctcagtgccctcca
attaagtttatcagtgcagatgtacatggaatttggtcaaggttattttgtgatttcggt
gatgaatttgaagttttagatacaacaggagaagaaccaaaagaaattttcatttcaaac
ataacgcaagcaaatcctggcattgttacttgccttgaaaatcatcctcacaaactggag
acaggacaattcctaacatttcgagaaattaatggaatgacaggtttaaatggatctata
caacaaataacggtgatatcgccattttcttttagtattggtgacaccacagaactggaa
ccatatttacatggaggcatagctgtccaagttaagactcctaaaacagttttttttgaa
tcactggagaggcagttaaaacatccaaagtgccttattgtggattttagcaaccctgag
gcacctttagagattcacacagctatgcttgccttggaccagtttcaggagaaatacagt
cgcaagccaaatgttggatgccaacaagattcagaagaactgttgaaactagcaacatct
ataagtgaaaccttggaagagaagcctgatgtaaatgctgacattgtgcattggctctct
tggactgcccaaggctttttatctccacttgctgcagcagtaggaggtgttgccagccaa
gaagtattgaaagctgtaacaggaaaattttctcctttgtgccagtggttatatcttgaa
gcagcagatattgttgaatcactaggcaaacctgaatgtgaagaatttctcccacgagga
gatagatatgatgccttaagagcttgcattggagacactttgtgtcagaaactgcaaaat
ttaaacatcttcttagtagggtgtggagccataggctgtgaaatgttgaaaaattttgct
ttacttggtgttggcacaagcaaagagaaaggaatgattacagttacagatcctgacttg
atagagaaatccaacttaaatagacagttcctatttcgtcctcatcacatacagaaacct
aaaagctacactgctgctgatgctactctgaaaataaattctcaaataaagatagatgca
cacctgaacaaagtatgtccaaccactgagaccatttacaatgatgagttctatactaaa
caagatgtaattattacagcattagataatgtggaagccaggagatacgtagacagtcgt
tgcttagcaaatctaaggcctcttttagattctggaacaatgggcactaagggacacact
gaagttattgtaccgcatttgactgagtcttacaatagtcatcgggatcccccagaagag
gaaataccattttgtactctaaaatcctttccagctgctattgaacataccatacagtgg
gcaagagataagtttgaaagttccttttcccacaaaccttcattgtttaacaaattttgg
caaacctattcatctgcagaagaagtcttacagaagatacagagtggacacagtttagaa
ggctgttttcaagttataaagttacttagcagaagacctagaaattggtcccagtgtgta
gaattagcaagattaaagtttgaaaaatattttaaccataaggctcttcagcttcttcac
tgtttccctctggacatacgattaaaagatggcagtttattttggcagtcaccaaagagg
ccaccctctccaataaaatttgatttaaatgagcctttgcacctcagtttccttcagaat
gctgcaaaactatatgctacagtatattgtattccatttgcagaagaggacttatcagca
gatgccctcttgaatattctttcagaagtaaagattcaggaattcaagccttccaataag
gttgttcaaacagatgaaactgcaaggaaaccagaccatgttcctattagcagtgaagat
gagaggaatgcaattttccaactagaaaaggctattttatctaatgaagccaccaaaagt
gaccttcagatggcagtgctttcatttgaaaaagatgatgatcataatggacacatagat
ttcatcacagctgcatcaaatcttcgtgccaaaatgtacagcattgaaccagctgaccgt
ttcaaaacaaagcgcatagctggtaaaattatacctgctatagcaacaaccactgctaca
gtttctggcttggttgccttggagatgatcaaagtaactggtggctatccatttgaagct
tacaaaaattgttttcttaacttagccattccaattgtagtatttacagagacaactgaa
gtaaggaaaactaaaatcagaaatggaatatcatttacaatttgggatcgatggaccgta
catggaaaagaagatttcaccctcttggatttcataaatgcagtcaaagagaagtatgga
attgagccaacaatggtggtacagggagtcaaaatgctttatgttcctgtaatgcctggt
catgcaaaaagattgaagttaacaatgcataaacttgtaaaacctactactgaaaagaaa
tatgtggatcttactgtgtcatttgctccagacattgatggagatgaagatttgccggga
cctccagtaagatactacttcagtcatgacactgattaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (37)   
   RefSeq(nuc) (5)   
   GenBank (16)   
   EMBL (16)   
3D Structure (3)   
   PDB (3)   
Protein domain (6)   
   Pfam (6)   
All databases (71)   

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