KEGG   Homo sapiens (human): 55240
Entry
55240             CDS       T01001                                 
Symbol
STEAP3, AHMIO2, STMP3, TSAP6, dudlin-2, dudulin-2, pHyde
Name
(RefSeq) STEAP3 metalloreductase
  KO
K10142  metalloreductase STEAP3 [EC:1.16.1.-]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04115  p53 signaling pathway
hsa04216  Ferroptosis
Network
nt06525  Ferroptosis
  Element
N01587  Fe-TF transport
Disease
H01196  Hypochromic microcytic anemia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04216 Ferroptosis
    55240 (STEAP3)
   04115 p53 signaling pathway
    55240 (STEAP3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    55240 (STEAP3)
Membrane trafficking [BR:hsa04131]
 Exocytosis
  Others
   Others
    55240 (STEAP3)
SSDB
Motif
Pfam: F420_oxidored Ferric_reduct NAD_binding_2 Shikimate_DH 2-Hacid_dh_C IlvN Leg1 Sacchrp_dh_NADP
Other DBs
NCBI-GeneID: 55240
NCBI-ProteinID: NP_001008410
OMIM: 609671
HGNC: 24592
Ensembl: ENSG00000115107
UniProt: Q658P3
Structure
Position
2:119223834..119265652
AA seq 488 aa
MPEEMDKPLISLHLVDSDSSLAKVPDEAPKVGILGSGDFARSLATRLVGSGFKVVVGSRN
PKRTARLFPSAAQVTFQEEAVSSPEVIFVAVFREHYSSLCSLSDQLAGKILVDVSNPTEQ
EHLQHRESNAEYLASLFPTCTVVKAFNVISAWTLQAGPRDGNRQVPICGDQPEAKRAVSE
MALAMGFMPVDMGSLASAWEVEAMPLRLLPAWKVPTLLALGLFVCFYAYNFVRDVLQPYV
QESQNKFFKLPVSVVNTTLPCVAYVLLSLVYLPGVLAAALQLRRGTKYQRFPDWLDHWLQ
HRKQIGLLSFFCAALHALYSFCLPLRRAHRYDLVNLAVKQVLANKSHLWVEEEVWRMEIY
LSLGVLALGTLSLLAVTSLPSIANSLNWREFSFVQSSLGFVALVLSTLHTLTYGWTRAFE
ESRYKFYLPPTFTLTLLVPCVVILAKALFLLPCISRRLARIRRGWERESTIKFTLPTDHA
LAEKTSHV
NT seq 1467 nt   +upstreamnt  +downstreamnt
atgccagaagagatggacaagccactgatcagcctccacctggtggacagcgatagtagc
cttgccaaggtccccgatgaggcccccaaagtgggcatcctgggtagcggggactttgcc
cgctccctggccacacgcctggtgggctctggcttcaaagtggtggtggggagccgcaac
cccaaacgcacagccaggctgtttccctcagcggcccaagtgactttccaagaggaggca
gtgagctccccggaggtcatctttgtggctgtgttccgggagcactactcttcactgtgc
agtctcagtgaccagctggcgggcaagatcctggtggatgtgagcaaccctacagagcaa
gagcaccttcagcatcgtgagtccaatgctgagtacctggcctccctcttccccacttgc
acagtggtcaaggccttcaatgtcatctctgcctggaccctgcaggctggcccaagggat
ggtaacaggcaggtgcccatctgcggtgaccagccagaagccaagcgtgctgtctcggag
atggcgctcgccatgggcttcatgcccgtggacatgggatccctggcgtcagcctgggag
gtggaggccatgcccctgcgcctcctcccggcctggaaggtgcccaccctgctggccctg
gggctcttcgtctgcttctatgcctacaacttcgtccgggacgttctgcagccctatgtg
caggaaagccagaacaagttcttcaagctgcccgtgtccgtggtcaacaccacactgccg
tgcgtggcctacgtgctgctgtcactcgtgtacttgcccggcgtgctggcggctgccctg
cagctgcggcgcggcaccaagtaccagcgcttccccgactggctggaccactggctacag
caccgcaagcagatcgggctgctcagcttcttctgcgccgccctgcacgccctctacagc
ttctgcttgccgctgcgccgcgcccaccgctacgacctggtcaacctggcagtcaagcag
gtcttggccaacaagagccacctctgggtggaggaggaggtctggcggatggagatctac
ctctccctgggagtgctggccctcggcacgttgtccctgctggccgtgacctcactgccg
tccattgcaaactcgctcaactggagggagttcagcttcgttcagtcctcactgggcttt
gtggccctcgtgctgagcacactgcacacgctcacctacggctggacccgcgccttcgag
gagagccgctacaagttctacctgcctcccaccttcacgctcacgctgctggtgccctgc
gtcgtcatcctggccaaagccctgtttctcctgccctgcatcagccgcagactcgccagg
atccggagaggctgggagagggagagcaccatcaagttcacgctgcccacagaccacgcc
ctggccgagaagacgagccacgtatga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Network (2)   
   KEGG NETWORK (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (10)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (8)   
DNA sequence (36)   
   RefSeq(nuc) (8)   
   GenBank (14)   
   EMBL (14)   
3D Structure (2)   
   PDB (2)   
Protein domain (8)   
   Pfam (8)   
All databases (78)   

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