KEGG   Homo sapiens (human): 55703
Entry
55703             CDS       T01001                                 
Symbol
POLR3B, C128, CMT1I, HLD8, INMAP, RPC2
Name
(RefSeq) RNA polymerase III subunit B
  KO
K03021  DNA-directed RNA polymerase III subunit RPC2 [EC:2.7.7.6]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03020  RNA polymerase
hsa04623  Cytosolic DNA-sensing pathway
Disease
H00264  Charcot-Marie-Tooth disease
H00679  Hypomyelinating leukodystrophy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09121 Transcription
   03020 RNA polymerase
    55703 (POLR3B)
 09150 Organismal Systems
  09151 Immune system
   04623 Cytosolic DNA-sensing pathway
    55703 (POLR3B)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:hsa03021]
    55703 (POLR3B)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.6  DNA-directed RNA polymerase
     55703 (POLR3B)
Transcription machinery [BR:hsa03021]
 Eukaryotic type
  RNA polymerase III system
   RNA polymerase III
    Core subunits
     55703 (POLR3B)
SSDB
Motif
Pfam: RNA_pol_Rpb2_6 RNA_pol_Rpb2_1 RNA_pol_Rpb2_7 RNA_pol_Rpb2_2 RNA_pol_Rpb2_4 RNA_pol_Rpb2_3 RNA_pol_Rpb2_5
Other DBs
NCBI-GeneID: 55703
NCBI-ProteinID: NP_060552
OMIM: 614366
HGNC: 30348
Ensembl: ENSG00000013503
UniProt: Q9NW08 Q7Z3R8
Structure
Position
12:106357748..106510198
AA seq 1133 aa
MDVLAEEFGNLTPEQLAAPIPTVEEKWRLLPAFLKVKGLVKQHIDSFNYFINVEIKKIMK
ANEKVTSDADPMWYLKYLNIYVGLPDVEESFNVTRPVSPHECRLRDMTYSAPITVDIEYT
RGSQRIIRNALPIGRMPIMLRSSNCVLTGKTPAEFAKLNECPLDPGGYFIVKGVEKVILI
QEQLSKNRIIVEADRKGAVGASVTSSTHEKKSRTNMAVKQGRFYLRHNTLSEDIPIVIIF
KAMGVESDQEIVQMIGTEEHVMAAFGPSLEECQKAQIFTQMQALKYIGNKVRRQRMWGGG
PKKTKIEEARELLASTILTHVPVKEFNFRAKCIYTAVMVRRVILAQGDNKVDDRDYYGNK
RLELAGQLLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDVVKHMRQDQITNGMVNAIS
TGNWSLKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGMLC
PSDTPEGEACGLVKNLALMTHITTDMEDGPIVKLASNLGVEDVNLLCGEELSYPNVFLVF
LNGNILGVIRDHKKLVNTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYIIVK
KQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLEIE
PFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQKPMV
KTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCTLK
RYTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQIPL
EGSNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKMLLRQTRRPEIGDKFSSR
HGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGRFHY
GTAFGGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKM
HARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISSDAFEVDVC
GQCGLLGYSGWCHYCKSSCHVSSLRIPYACKLLFQELQSMNIIPRLKLSKYNE
NT seq 3402 nt   +upstreamnt  +downstreamnt
atggacgtgctagcggaggagtttgggaacctgactccggagcagctggcggcgccgatc
ccgactgtagaggaaaaatggaggctgcttccagcatttttaaaggtgaaaggccttgtg
aaacagcatatagattcatttaactatttcattaatgtagagataaagaagataatgaaa
gccaatgaaaaggttacaagtgacgctgaccctatgtggtacttaaaatatcttaatatc
tatgttgggcttcctgatgttgaagaaagcttcaatgtaactagaccagtgtcccctcat
gagtgccgtttgagagacatgacatactctgcccctattacagtggatattgaatatacc
cgaggcagccagaggatcatccgcaatgccttacctatcggcagaatgcccataatgcta
cgtagttcaaactgtgttcttacaggaaaaacgccagcagaatttgccaaactgaacgaa
tgtcccttagatccaggtggctacttcattgttaaaggagtagaaaaagttattcttatc
caagagcagctgtctaagaacaggatcatcgtggaggctgatagaaaaggggctgttgga
gcttcagttaccagctctacccatgagaaaaaaagcagaaccaatatggctgtgaaacaa
ggacgattttatttgaggcataatactttgtcagaagatatacccattgtcatcatattt
aaggccatgggtgttgagagtgaccaggaaattgtgcagatgattggaacagaggagcac
gtgatggctgcatttgggcccagtctggaagagtgccagaaagctcagattttcacacag
atgcaggcattaaaatatatagggaacaaagtaagaaggcaaaggatgtggggaggtgga
ccaaagaaaaccaaaatagaagaagcaagagagctcctggcttccaccattctgacccat
gtcccagttaaggaattcaatttccgagccaaatgtatctatactgcagtgatggtgcga
agagttattctggcccaaggagataataaagttgacgacagagattattatggtaacaag
cgactggaattggcaggacagcttttatctcttctttttgaagacttgttcaaaaaattt
aattctgaaatgaaaaagattgccgaccaggtgattcctaagcaaagagcagcccagttt
gatgttgtcaaacacatgcgccaagaccagatcaccaatggcatggtgaatgctatttct
accggaaattggtctttaaagagatttaaaatggaccgccagggtgtaacccaagtgctg
tctcgcttgtcatatatatccgcactgggcatgatgacaagaatctcttcccagtttgaa
aaaacgagaaaagtgagtggtcctcgctccctccagccatctcagtggggaatgctgtgt
ccttcggacactcctgaaggagaggcatgtggtttggttaaaaacttggcccttatgaca
cacatcacaactgatatggaagatggacccattgttaaattagccagtaacttgggagta
gaagatgtgaatttattatgtggggaagagctctcttacccaaatgtgtttcttgtcttt
cttaatggtaacatcttaggtgtcattcgagaccacaaaaagctagtgaatacatttcga
ctcatgagaagagcaggatatatcaatgaatttgtttccatctcaacaaatcttacagat
cgatgtgtctatatttcttctgatgggggaaggctatgcagaccctacataattgtcaag
aaacagaagccagcagtcacaaataaacatatggaagagctggcccaagggtacaggaat
tttgaagatttcttacatgagagtctggttgaatatttagatgtgaatgaagaaaatgat
tgtaacattgcactgtacgaacacacaattaataaagacaccacccacttggagattgaa
cccttcactcttctcggcgtgtgtgctggacttatcccataccctcaccataaccagtca
ccgagaaacacttatcagtgtgccatggggaaacaagccatgggtactataggatacaac
cagcgaaacagaattgatactctcatgtatctactagcatatccacaaaaacccatggtt
aagacaaaaaccattgaattgatagaatttgagaaactgccagctggacagaatgcaaca
gttgctgtgatgagctatagtggctatgatattgaagatgctcttgttttaaacaaggcc
tctttagacagaggctttgggcgttgccttgtatataaaaatgctaaatgtacgttgaaa
cgatacaccaatcagacttttgataaagtgatggggcccatgttggatgctgctacaagg
aaacctatctggcgacatgaaatcttagatgcagatggtatttgttctccaggtgagaaa
gtagaaaacaaacaagtgcttgtaaataagtccatgcccacagtgactcagattcctttg
gaaggaagtaatgtaccacagcaaccacagtacaaagatgtacccataacctacaaagga
gcaacagactcatatattgaaaaagtgatgatatcttcaaatgctgaagatgcttttctg
atcaaaatgctgctgagacagacaaggcgtccagaaattggagacaaattcagcagtcgt
catgggcaaaaaggtgtttgtggcttgatcgtcccccaggaagacatgccattttgtgat
tctggcatctgtccggacatcatcatgaacccacacggcttcccatcacgaatgacggtg
gggaagctcattgagctgctggctggcaaggccggtgtgctggacggcagattccactac
ggcactgcgtttggaggcagtaaagtgaaggatgtgtgtgaggacctcgttcgccatggt
tataactacttggggaaagactatgttacatccggcatcacaggtgagcccttagaagca
tacatctattttggccccgtgtactatcagaagctgaaacacatggtgctagataaaatg
catgcccgggcccggggcccacgagccgtccttaccaggcaacccactgaaggacggtct
cgtgatggtggcttgcgtctcggggaaatggaacgtgactgtttaatcggttatggagcc
agtatgcttttgctagagagactaatgatttcaagtgatgcctttgaggttgatgtctgt
gggcagtgtggacttctggggtattctggctggtgccattactgcaagtcatcctgccac
gtgtcttccctccgtattccgtatgcctgcaagctgctcttccaggaactacagtctatg
aacatcatccccaggttaaaactgtccaagtacaatgaatga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (6)   
   KEGG DISEASE (2)   
   OMIM (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (24)   
   KEGG ORTHOLOGY (1)   
   RefGene (14)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (7)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (36)   
   RefSeq(nuc) (4)   
   GenBank (16)   
   EMBL (16)   
3D Structure (14)   
   PDB (14)   
Protein domain (7)   
   Pfam (7)   
All databases (101)   

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