KEGG   Homo sapiens (human): 5617
Entry
5617              CDS       T01001                                 
Symbol
PRL, GHA1
Name
(RefSeq) prolactin
  KO
K05439  prolactin
Organism
hsa  Homo sapiens (human)
Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04080  Neuroactive ligand-receptor interaction
hsa04151  PI3K-Akt signaling pathway
hsa04630  JAK-STAT signaling pathway
hsa04917  Prolactin signaling pathway
Network
nt06325  Hormone/cytokine signaling
nt06518  JAK-STAT signaling
  Element
N00920  PRL-JAK-STAT signaling pathway
N01555  Hormone-like-cytokine to Jak-STAT signaling pathway
Drug target
Bromocriptine (DG00452): D00780<JP/US> D03165
Cabergoline: D00987<JP/US>
Terguride: D01348
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    5617 (PRL)
   04151 PI3K-Akt signaling pathway
    5617 (PRL)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    5617 (PRL)
   04060 Cytokine-cytokine receptor interaction
    5617 (PRL)
 09150 Organismal Systems
  09152 Endocrine system
   04917 Prolactin signaling pathway
    5617 (PRL)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:hsa04052]
    5617 (PRL)
Cytokines and neuropeptides [BR:hsa04052]
 Neuropeptides
  Neuropeptides (Unclassified)
   5617 (PRL)
SSDB
Motif
Pfam: Hormone_1
Other DBs
NCBI-GeneID: 5617
NCBI-ProteinID: NP_000939
OMIM: 176760
HGNC: 9445
Ensembl: ENSG00000172179
CPD: C18201
UniProt: P01236 Q5THQ0
Structure
Position
6:complement(22287246..22302835)
AA seq 227 aa
MNIKGSPWKGSLLLLLVSNLLLCQSVAPLPICPGGAARCQVTLRDLFDRAVVLSHYIHNL
SSEMFSEFDKRYTHGRGFITKAINSCHTSSLATPEDKEQAQQMNQKDFLSLIVSILRSWN
EPLYHLVTEVRGMQEAPEAILSKAVEIEEQTKRLLEGMELIVSQVHPETKENEIYPVWSG
LPSLQMADEESRLSAYYNLLHCLRRDSHKIDNYLKLLKCRIIHNNNC
NT seq 684 nt   +upstreamnt  +downstreamnt
atgaacatcaaaggatcgccatggaaagggtccctcctgctgctgctggtgtcaaacctg
ctcctgtgccagagcgtggcccccttgcccatctgtcccggcggggctgcccgatgccag
gtgacccttcgagacctgtttgaccgcgccgtcgtcctgtcccactacatccataacctc
tcctcagaaatgttcagcgaattcgataaacggtatacccatggccgggggttcattacc
aaggccatcaacagctgccacacttcttcccttgccacccccgaagacaaggagcaagcc
caacagatgaatcaaaaagactttctgagcctgatagtcagcatattgcgatcctggaat
gagcctctgtatcatctggtcacggaagtacgtggtatgcaagaagccccggaggctatc
ctatccaaagctgtagagattgaggagcaaaccaaacggcttctagagggcatggagctg
atagtcagccaggttcatcctgaaaccaaagaaaatgagatctaccctgtctggtcggga
cttccatccctgcagatggctgatgaagagtctcgcctttctgcttattataacctgctc
cactgcctacgcagggattcacataaaatcgacaattatctcaagctcctgaagtgccga
atcatccacaacaacaactgctaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (5)   
Network (4)   
   KEGG NETWORK (4)   
Disease (1)   
   OMIM (1)   
Drug (4)   
   KEGG DRUG (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (13)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (10)   
DNA sequence (36)   
   RefSeq(nuc) (10)   
   GenBank (13)   
   EMBL (13)   
3D Structure (12)   
   PDB (12)   
Protein domain (1)   
   Pfam (1)   
All databases (93)   

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