KEGG   Homo sapiens (human): 5645
Entry
5645              CDS       T01001                                 
Symbol
PRSS2, TRY2, TRY8, TRYP2
Name
(RefSeq) serine protease 2
  KO
K01312  trypsin [EC:3.4.21.4]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04972  Pancreatic secretion
hsa04974  Protein digestion and absorption
hsa05164  Influenza A
Disease
H00933  Hereditary pancreatitis
Drug target
Ulinastatin: D05183<JP>
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    5645 (PRSS2)
 09150 Organismal Systems
  09154 Digestive system
   04972 Pancreatic secretion
    5645 (PRSS2)
   04974 Protein digestion and absorption
    5645 (PRSS2)
 09160 Human Diseases
  09172 Infectious disease: viral
   05164 Influenza A
    5645 (PRSS2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    5645 (PRSS2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    5645 (PRSS2)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.4  trypsin
     5645 (PRSS2)
Peptidases and inhibitors [BR:hsa01002]
 Serine peptidases
  Family S1: chymotrypsin family
   5645 (PRSS2)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   5645 (PRSS2)
SSDB
Motif
Pfam: Trypsin Trypsin_2 DUF1986
Other DBs
NCBI-GeneID: 5645
NCBI-ProteinID: NP_002761
OMIM: 601564
HGNC: 9483
Ensembl: ENSG00000275896
UniProt: P07478 Q5NV56 Q6PK75
Position
7:142770970..142774560
AA seq 247 aa
MNLLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNSGYHFCGGSLISEQWVVS
AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVIN
SRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKIT
NNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGYGCAQKNRPGVYTKVYNYVDWIK
DTIAANS
NT seq 744 nt   +upstreamnt  +downstreamnt
atgaatctacttctgatccttacctttgttgcagctgctgttgctgccccctttgatgat
gatgacaagatcgttgggggctacatctgtgaggagaattctgtcccctaccaggtgtcc
ttgaattctggctaccacttctgcggtggctccctcatcagcgaacagtgggtggtgtca
gcaggtcactgctacaagtcccgcatccaggtgagactgggagagcacaacatcgaagtc
ctggaggggaatgaacagttcatcaatgcggccaagatcatccgccaccccaaatacaac
agccggactctggacaatgacatcctgctgatcaagctctcctcacctgccgtcatcaat
tcccgcgtgtccgccatctctctgcccactgcccctccagctgctggcaccgagtccctc
atctccggctggggcaacactctgagttctggtgccgactacccagacgagctgcagtgc
ctggatgctcctgtgctgagccaggctgagtgtgaagcctcctaccctggaaagattacc
aacaacatgttctgtgtgggcttcctcgagggaggcaaggattcctgccagggtgattct
ggtggccctgtggtctccaatggagagctccaaggaattgtctcctggggctatggctgt
gcccagaagaacaggcctggagtctacaccaaggtctacaactatgtggactggattaag
gacaccatagctgccaacagctaa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (4)   
   KEGG PATHWAY (4)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Drug (1)   
   KEGG DRUG (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (7)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (26)   
   RefSeq(nuc) (4)   
   GenBank (11)   
   EMBL (11)   
Protein domain (3)   
   Pfam (3)   
All databases (62)   

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