KEGG   Homo sapiens (human): 56474
Entry
56474             CDS       T01001                                 
Symbol
CTPS2, GATD5B
Name
(RefSeq) CTP synthase 2
  KO
K01937  CTP synthase [EC:6.3.4.2]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00240  Pyrimidine metabolism
hsa01100  Metabolic pathways
hsa01232  Nucleotide metabolism
hsa01240  Biosynthesis of cofactors
Module
hsa_M00052  Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    56474 (CTPS2)
Enzymes [BR:hsa01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.2  CTP synthase (glutamine hydrolysing)
     56474 (CTPS2)
SSDB
Motif
Pfam: CTP_synth_N GATase Peptidase_C26 CbiA DUF2469 Transket_pyr
Other DBs
NCBI-GeneID: 56474
NCBI-ProteinID: NP_001137474
OMIM: 300380
HGNC: 2520
Ensembl: ENSG00000047230
UniProt: Q9NRF8
Structure
Position
X:complement(16587999..16712910)
AA seq 586 aa
MKYILVTGGVISGIGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEHGEVFV
LNDGGEVDLDLGNYERFLDINLYKDNNITTGKIYQHVINKERRGDYLGKTVQVVPHITDA
VQEWVMNQAKVPVDGNKEEPQICVIELGGTIGDIEGMPFVEAFRQFQFKAKRENFCNIHV
SLVPQLSATGEQKTKPTQNSVRALRGLGLSPDLIVCRSSTPIEMAVKEKISMFCHVNPEQ
VICIHDVSSTYRVPVLLEEQSIVKYFKERLHLPIGDSASNLLFKWRNMADRYERLQKICS
IALVGKYTKLRDCYASVFKALEHSALAINHKLNLMYIDSIDLEKITETEDPVKFHEAWQK
LCKADGILVPGGFGIRGTLGKLQAISWARTKKIPFLGVCLGMQLAVIEFARNCLNLKDAD
STEFRPNAPVPLVIDMPEHNPGNLGGTMRLGIRRTVFKTENSILRKLYGDVPFIEERHRH
RFEVNPNLIKQFEQNDLSFVGQDVDGDRMEIIELANHPYFVGVQFHPEFSSRPMKPSPPY
LGLLLAATGNLNAYLQQGCKLSSSDRYSDASDDSFSEPRIAELEIS
NT seq 1761 nt   +upstreamnt  +downstreamnt
atgaagtacatcctggtcacgggtggggtcatctcaggcattggtaaagggatcattgcc
agcagcattggaacgattctaaaatcatgtggactccgagttactgccataaaaatcgac
ccctatattaacatcgatgctggcactttttcaccttatgaacacggtgaagtcttcgtc
ttaaatgatggtggagaagttgatttagaccttggaaattatgaaagatttttggatatt
aatctttataaagacaacaatatcaccacggggaagatatatcagcatgtgatcaataaa
gagaggcgtggtgattacctggggaaaacagtgcaagttgtccctcacattactgatgct
gtccaggagtgggttatgaatcaagccaaggtgccggtggatggtaataaggaagagccc
caaatatgcgttattgagctgggaggcaccattggagacatcgaaggaatgccgtttgtg
gaggcgtttagacaattccagtttaaggcgaaaagagagaatttctgtaatatccacgtt
agccttgtcccacagctcagtgctaccggagaacaaaaaaccaaacccacccaaaacagc
gtccgcgcactgaggggtttaggcctgtctccagatctgattgtctgccgaagttcaacg
cccattgagatggccgtgaaggagaagatttctatgttttgtcacgtgaaccctgaacag
gtcatatgtatccatgatgtttcttccacataccgagttcctgtgcttttagaggaacaa
agcattgtgaaatattttaaggagagattgcacctgcccatcggtgattctgcaagtaat
ttgctttttaagtggagaaatatggctgacaggtatgaaaggttacagaaaatatgctcc
atagccctggttggcaaatacaccaagctcagagactgctacgcctctgtgttcaaagcc
ctggaacactcagccctggccatcaaccacaagttgaatctgatgtacatagactccatt
gatctggagaagatcactgaaaccgaggaccctgtgaaatttcatgaagcttggcagaag
ctatgcaaagctgatggtattcttgtgcctggaggctttggaatcagaggaacattggga
aaactccaggcgatttcttgggcaaggacaaagaagattccttttctgggagtttgtctt
gggatgcaactagcagtgatagagtttgcaagaaactgccttaacttgaaagatgctgat
tccacagagtttaggccaaatgccccagttcctctggtgattgatatgcccgagcacaac
cctggcaatttgggaggaacaatgagactgggaataagaagaactgttttcaaaactgaa
aattcaatattaaggaaactttatggtgatgttccttttatagaagaaagacacagacat
cggttcgaggtaaaccctaacctgatcaaacaatttgagcagaatgacttaagttttgta
ggtcaggatgttgatggagacaggatggaaatcattgaactggcaaatcatccttatttt
gttggtgtccagttccatcctgagttttcttctaggccgatgaagccttcccctccgtat
ctggggctgttacttgcagcaactgggaacctgaatgcctacttgcaacagggttgcaaa
ctgtcttccagtgatagatacagtgatgccagtgatgacagcttttcagagccaaggata
gctgagttggaaataagctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Disease (1)   
   OMIM (1)   
Chemical substance (9)   
   KEGG COMPOUND (9)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   RefGene (12)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (17)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (15)   
DNA sequence (41)   
   RefSeq(nuc) (15)   
   GenBank (13)   
   EMBL (13)   
3D Structure (8)   
   PDB (8)   
Protein domain (6)   
   Pfam (6)   
All databases (113)   

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