KEGG   Homo sapiens (human): 56852
Entry
56852             CDS       T01001                                 
Symbol
RAD18, RNF73
Name
(RefSeq) RAD18 E3 ubiquitin protein ligase
  KO
K10627  E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
Organism
hsa  Homo sapiens (human)
Network
nt06506  Double-strand break repair
  Element
N01636  Loading of the SMC5-SMC6 complex
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    56852 (RAD18)
   03400 DNA repair and recombination proteins [BR:hsa03400]
    56852 (RAD18)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     56852 (RAD18)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   Other single Ring-finger type E3
    56852 (RAD18)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  TLS (translesion DNA synthesis) factors
   Rad6 epistasis group
    56852 (RAD18)
SSDB
Motif
Pfam: SAP zf-C3HC4_2 zf-C3HC4 zf-RING_6 zf-RING_2 zf-C3HC4_3 zf-RING_UBOX zf-RING_5 zf-WRNIP1_ubi CpG_bind_C PhoU_div zf-rbx1 LEM zf-RING_10 Rad50_zn_hook
Other DBs
NCBI-GeneID: 56852
NCBI-ProteinID: NP_064550
OMIM: 605256
HGNC: 18278
Ensembl: ENSG00000070950
UniProt: Q9NS91
Structure
Position
3:complement(8877075..8963472)
AA seq 495 aa
MDSLAESRWPPGLAVMKTIDDLLRCGICFEYFNIAMIIPQCSHNYCSLCIRKFLSYKTQC
PTCCVTVTEPDLKNNRILDELVKSLNFARNHLLQFALESPAKSPASSSSKNLAVKVYTPV
ASRQSLKQGSRLMDNFLIREMSGSTSELLIKENKSKFSPQKEASPAAKTKETRSVEEIAP
DPSEAKRPEPPSTSTLKQVTKVDCPVCGVNIPESHINKHLDSCLSREEKKESLRSSVHKR
KPLPKTVYNLLSDRDLKKKLKEHGLSIQGNKQQLIKRHQEFVHMYNAQCDALHPKSAAEI
VREIENIEKTRMRLEASKLNESVMVFTKDQTEKEIDEIHSKYRKKHKSEFQLLVDQARKG
YKKIAGMSQKTVTITKEDESTEKLSSVCMGQEDNMTSVTNHFSQSKLDSPEELEPDREED
SSSCIDIQEVLSSSESDSCNSSSSDIIRDLLEEEEAWEASHKNDLQDTEISPRQNRRTRA
AESAEIEPRNKRNRN
NT seq 1488 nt   +upstreamnt  +downstreamnt
atggactccctggccgagtctcggtggcctccgggcctggcagtcatgaagacaatagat
gatttgctgcggtgtggaatttgcttcgagtatttcaacattgcaatgataatacctcag
tgttcacataactactgctctctctgtataagaaaatttctgtcctataaaactcagtgt
ccaacttgctgtgtgactgtcacagagccggatctgaaaaataaccgcatattagatgaa
ctggtaaaaagcttgaattttgcacggaatcatctgctgcagtttgctttagagtcacca
gccaaatctcctgcttcttcctcttcaaagaatcttgctgtcaaagtatatactcctgta
gcctccagacagtctttaaagcaggggagcaggttaatggataatttcttgatcagagaa
atgagtggttctacatcagagttgttgataaaagaaaataaaagcaaattcagccctcaa
aaagaggcgagccctgctgcaaagaccaaagagacacgttctgtagaagagatcgctcca
gatccctcagaggctaagcgtcctgagccaccctcgacatccactttgaaacaagttact
aaagtggattgtcctgtttgcggggttaacattccagaaagtcacattaataagcattta
gacagctgtttatcacgcgaagagaagaaggaaagcctcagaagttctgttcacaaaagg
aagccgctgcccaaaactgtatataatttgctctctgatcgtgatttaaagaaaaagcta
aaagagcatggattatctattcaaggaaataaacaacagctcattaaaaggcaccaagaa
tttgtacacatgtacaatgcccaatgcgatgctttgcatcctaaatcagctgctgaaata
gttcgagaaatcgaaaatatagagaagactaggatgcgtcttgaagctagtaaactcaat
gaaagtgtaatggtttttacaaaggaccaaacagaaaaggaaatagatgaaatccacagt
aaatatcgtaaaaaacataagagtgaatttcagcttctggtggatcaggctagaaaagga
tacaagaaaattgctggaatgtcacaaaaaacagtaacaataacaaaagaagatgaatct
acagaaaagctatcttctgtatgcatgggacaggaagataatatgacctcagtaacaaac
cacttttctcaatcaaagctggactccccagaggaattggaacctgacagagaagaggat
tcttctagctgtattgatattcaagaagttctttcttcatcagaatcagattcatgcaat
agttccagttcagacatcataagagatcttttagaagaagaggaagcctgggaagcatca
cataaaaacgatcttcaagacacagaaataagtccaagacagaatcgccgcacaagagcc
gctgaaagtgctgagattgaaccaagaaacaagcgtaataggaattaa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   RefGene (12)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (20)   
   RefSeq(nuc) (4)   
   GenBank (8)   
   EMBL (8)   
3D Structure (5)   
   PDB (5)   
Protein domain (15)   
   Pfam (15)   
All databases (76)   

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