KEGG   Homo sapiens (human): 56903
Entry
56903             CDS       T01001                                 
Symbol
PAPOLB, PAPT, TPAP
Name
(RefSeq) poly(A) polymerase beta
  KO
K14376  poly(A) polymerase [EC:2.7.7.19]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03015  mRNA surveillance pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    56903 (PAPOLB)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    56903 (PAPOLB)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.19  polynucleotide adenylyltransferase
     56903 (PAPOLB)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA processing factors
   3' end processing
    Poly(A) addition factors
     56903 (PAPOLB)
SSDB
Motif
Pfam: PAP_NTPase PAP_central PAP_RNA-bind NTP_transf_2 Polbeta
Other DBs
NCBI-GeneID: 56903
NCBI-ProteinID: NP_064529
OMIM: 607436
HGNC: 15970
Ensembl: ENSG00000218823
UniProt: Q9NRJ5 A4D1Z6
Position
7:complement(4857738..4862030)
AA seq 637 aa
MMPFPVTTQGPPQPAPPPNRYGVSSPISLAVPKETDCLLTQRLIETLRPFGVFEEEEELQ
RRILVLEKLNNLVKEWIREISESKSLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCV
APSHVDRSDFFTSFYAKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIP
EDLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKCHNIYSN
ILGFLGGVSWAMLVARTCQLYPNAVASTLVRKFFLVFSEWEWPNPVLLKEPEERNLNLPV
WDPRVNPSDRYHLMPIITPAYPQQNSTYNVSISTRMVMIEEFKQGLAITHEILLSKAEWS
KLFEAPSFFQKYKHYIVLLASASTEKQHLEWVGLVESKIRILVGSLEKNEFITLAHVNPQ
SFPAPKENPDMEEFRTMWVIGLGLKKPDNSEILSIDLTYDIQSFTDTVYRQAVNSKMFEM
GMKITAMHLRRKELHQLLPHHVLQDKKAHSTEGRRLTDLNDSSFDLSAGCENSMSVPSST
STMKTGPLISSSQGRNSPALAVMTASVANIQATEFSLQQVNTNESSGVALNESIPHAVSQ
PAISPSPKAMVARVVSSTCLISHPDLQETQQQTYLIL
NT seq 1914 nt   +upstreamnt  +downstreamnt
atgatgccgtttccggtgacaacccagggaccaccgcagccggcgccgccgccgaatcgc
tacggcgtctcctcgcctatcagtctagcggtccccaaggagacggactgcctcctcacc
cagaggctaatagaaaccctcaggcccttcggggtcttcgaagaggaagaggaactgcag
cgcaggattttagttttggaaaaattaaataatctggtaaaggaatggatacgcgaaatc
agtgaaagcaagagtcttccccagtctgtaattgaaaacgttggaggaaagatttttacg
tttggctcttacagattaggagtacatacgaaaggcgcagatattgacgccttgtgcgtt
gcaccaagtcatgtggatcgaagcgactttttcacctcattctatgctaaactgaaacta
caggaggaagtgaaagatttaagggctgtcgaggaggcatttgtgccagttatcaaactg
tgttttgatgggatagagattgatattttatttgcaagattagcactacagactattcca
gaagatttggacttaagagatgacagtctacttaaaaatttagacattagatgcataaga
agccttaatggttgccgggtaaccgatgaaattttacatctagtgccaaacattgacaac
ttcaggctgactctgagagccatcaaactgtgggccaagtgccacaatatctattccaat
atattaggtttcctcggaggtgtttcctgggccatgctagtagcaagaacttgtcagctt
tatccaaatgcagtagcgtcaactcttgtacggaaattcttcttggtattttcagaatgg
gaatggccaaacccagtgttactgaaggagcctgaagaacggaatcttaatttgcctgta
tgggacccaagagtaaatcccagtgataggtaccatcttatgcctatcatcacaccagca
tacccacagcagaactccacatacaacgtgtctatttcaaccaggatggtcatgattgag
gagtttaaacaggggcttgctatcacacacgagattttgctaagtaaggcagagtggtcc
aaactctttgaagctccaagcttctttcaaaagtacaagcattatattgtacttctggca
agtgcatcaacagaaaaacaacatttagaatgggtgggcttggtggaatcaaagatccga
atcctggttgggagcttggagaagaatgaatttattacactggcacatgtgaatccacag
tcatttccagcacccaaagaaaatcctgatatggaagaatttcgtacaatgtgggtgatt
gggttagggctaaaaaagccagataattctgaaattctcagcattgatctcacctatgat
atccagtctttcacagatactgtttataggcaagcagtgaatagtaagatgtttgagatg
ggtatgaaaattactgcaatgcatttaagaagaaaggaacttcaccagctgctgcctcat
catgtgcttcaggacaagaaagcacactcaacagaaggtagaagattgacagatttgaac
gacagcagctttgacttgtctgcaggctgtgaaaacagcatgtctgtgccttcatctact
agcactatgaagacaggcccattgattagcagttctcagggtagaaacagtcctgccttg
gctgtaatgacagcatctgtggctaacatacaggctactgaattttccttgcaacaggtg
aataccaatgaaagttcaggggttgcattaaacgaaagtattcctcacgctgtctctcag
cctgccatttctccatcaccaaaggccatggtcgccagagttgtttcttcaacatgtctc
ataagccatccagaccttcaggaaactcagcaacaaacatatctaatcctatag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (9)   
   OC (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (7)   
   RefSeq(nuc) (1)   
   GenBank (3)   
   EMBL (3)   
Protein domain (5)   
   Pfam (5)   
All databases (40)   

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