KEGG   Homo sapiens (human): 57142
Entry
57142             CDS       T01001                                 
Symbol
RTN4, ASY, NI220/250, NOGO, NSP, NSP-CL, Nbla00271, Nbla10545, RTN-X, RTN4-A, RTN4-B1, RTN4-B2, RTN4-C
Name
(RefSeq) reticulon 4
  KO
K20720  reticulon-4
Organism
hsa  Homo sapiens (human)
Pathway
hsa05010  Alzheimer disease
Drug target
Ozanezumab: D10331
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    57142 (RTN4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    57142 (RTN4)
   03036 Chromosome and associated proteins [BR:hsa03036]
    57142 (RTN4)
Membrane trafficking [BR:hsa04131]
 Endoplasmic reticulum (ER) - Golgi transport
  Others
   Others
    57142 (RTN4)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centrosome formation proteins
   Spindle formation proteins
    57142 (RTN4)
SSDB
Motif
Pfam: Reticulon DUF639
Other DBs
NCBI-GeneID: 57142
NCBI-ProteinID: NP_065393
OMIM: 604475
HGNC: 14085
Ensembl: ENSG00000115310
UniProt: Q9NQC3
Structure
Position
2:complement(54972189..55137831)
AA seq 1192 aa
MEDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPA
AGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAP
SPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRG
SSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLLETAASLPSLSP
LSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELEYSEM
GSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKEDEVV
SSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNLESKV
DKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIATNIF
PLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLTKVTE
EVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQLCPSF
EESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENPPPYE
EAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFSDYSE
MAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSFESMI
EYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELSTAVY
SNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSHKSEI
ANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVSALAT
QAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKKTGVV
FGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESE
VAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTL
LILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
NT seq 3579 nt   +upstreamnt  +downstreamnt
atggaagacctggaccagtctcctctggtctcgtcctcggacagcccaccccggccgcag
cccgcgttcaagtaccagttcgtgagggagcccgaggacgaggaggaagaagaggaggag
gaagaggaggacgaggacgaagacctggaggagctggaggtgctggagaggaagcccgcc
gccgggctgtccgcggccccagtgcccaccgcccctgccgccggcgcgcccctgatggac
ttcggaaatgacttcgtgccgccggcgccccggggacccctgccggccgctccccccgtc
gccccggagcggcagccgtcttgggacccgagcccggtgtcgtcgaccgtgcccgcgcca
tccccgctgtctgctgccgcagtctcgccctccaagctccctgaggacgacgagcctccg
gcccggcctccccctcctcccccggccagcgtgagcccccaggcagagcccgtgtggacc
ccgccagccccggctcccgccgcgcccccctccaccccggccgcgcccaagcgcaggggc
tcctcgggctcagtggatgagaccctttttgctcttcctgctgcatctgagcctgtgata
cgctcctctgcagaaaatatggacttgaaggagcagccaggtaacactatttcggctggt
caagaggatttcccatctgtcctgcttgaaactgctgcttctcttccttctctgtctcct
ctctcagccgcttctttcaaagaacatgaataccttggtaatttgtcaacagtattaccc
actgaaggaacacttcaagaaaatgtcagtgaagcttctaaagaggtctcagagaaggca
aaaactctactcatagatagagatttaacagagttttcagaattagaatactcagaaatg
ggatcatcgttcagtgtctctccaaaagcagaatctgccgtaatagtagcaaatcctagg
gaagaaataatcgtgaaaaataaagatgaagaagagaagttagttagtaataacatcctt
cataatcaacaagagttacctacagctcttactaaattggttaaagaggatgaagttgtg
tcttcagaaaaagcaaaagacagttttaatgaaaagagagttgcagtggaagctcctatg
agggaggaatatgcagacttcaaaccatttgagcgagtatgggaagtgaaagatagtaag
gaagatagtgatatgttggctgctggaggtaaaatcgagagcaacttggaaagtaaagtg
gataaaaaatgttttgcagatagccttgagcaaactaatcacgaaaaagatagtgagagt
agtaatgatgatacttctttccccagtacgccagaaggtataaaggatcgttcaggagca
tatatcacatgtgctccctttaacccagcagcaactgagagcattgcaacaaacattttt
cctttgttaggagatcctacttcagaaaataagaccgatgaaaaaaaaatagaagaaaag
aaggcccaaatagtaacagagaagaatactagcaccaaaacatcaaacccttttcttgta
gcagcacaggattctgagacagattatgtcacaacagataatttaacaaaggtgactgag
gaagtcgtggcaaacatgcctgaaggcctgactccagatttagtacaggaagcatgtgaa
agtgaattgaatgaagttactggtacaaagattgcttatgaaacaaaaatggacttggtt
caaacatcagaagttatgcaagagtcactctatcctgcagcacagctttgcccatcattt
gaagagtcagaagctactccttcaccagttttgcctgacattgttatggaagcaccattg
aattctgcagttcctagtgctggtgcttccgtgatacagcccagctcatcaccattagaa
gcttcttcagttaattatgaaagcataaaacatgagcctgaaaaccccccaccatatgaa
gaggccatgagtgtatcactaaaaaaagtatcaggaataaaggaagaaattaaagagcct
gaaaatattaatgcagctcttcaagaaacagaagctccttatatatctattgcatgtgat
ttaattaaagaaacaaagctttctgctgaaccagctccggatttctctgattattcagaa
atggcaaaagttgaacagccagtgcctgatcattctgagctagttgaagattcctcacct
gattctgaaccagttgacttatttagtgatgattcaatacctgacgttccacaaaaacaa
gatgaaactgtgatgcttgtgaaagaaagtctcactgagacttcatttgagtcaatgata
gaatatgaaaataaggaaaaactcagtgctttgccacctgagggaggaaagccatatttg
gaatcttttaagctcagtttagataacacaaaagataccctgttacctgatgaagtttca
acattgagcaaaaaggagaaaattcctttgcagatggaggagctcagtactgcagtttat
tcaaatgatgacttatttatttctaaggaagcacagataagagaaactgaaacgttttca
gattcatctccaattgaaattatagatgagttccctacattgatcagttctaaaactgat
tcattttctaaattagccagggaatatactgacctagaagtatcccacaaaagtgaaatt
gctaatgccccggatggagctgggtcattgccttgcacagaattgccccatgacctttct
ttgaagaacatacaacccaaagttgaagagaaaatcagtttctcagatgacttttctaaa
aatgggtctgctacatcaaaggtgctcttattgcctccagatgtttctgctttggccact
caagcagagatagagagcatagttaaacccaaagttcttgtgaaagaagctgagaaaaaa
cttccttccgatacagaaaaagaggacagatcaccatctgctatattttcagcagagctg
agtaaaacttcagttgttgacctcctgtactggagagacattaagaagactggagtggtg
tttggtgccagcctattcctgctgctttcattgacagtattcagcattgtgagcgtaaca
gcctacattgccttggccctgctctctgtgaccatcagctttaggatatacaagggtgtg
atccaagctatccagaaatcagatgaaggccacccattcagggcatatctggaatctgaa
gttgctatatctgaggagttggttcagaagtacagtaattctgctcttggtcatgtgaac
tgcacgataaaggaactcaggcgcctcttcttagttgatgatttagttgattctctgaag
tttgcagtgttgatgtgggtatttacctatgttggtgccttgtttaatggtctgacacta
ctgattttggctctcatttcactcttcagtgttcctgttatttatgaacggcatcaggca
cagatagatcattatctaggacttgcaaataagaatgttaaagatgctatggctaaaatc
caagcaaaaatccctggattgaagcgcaaagctgaatga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Drug (1)   
   KEGG DRUG (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (50)   
   KEGG ORTHOLOGY (1)   
   RefGene (26)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (18)   
   OC (1)   
Protein sequence (13)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (11)   
DNA sequence (121)   
   RefSeq(nuc) (13)   
   GenBank (54)   
   EMBL (54)   
3D Structure (2)   
   PDB (2)   
Protein domain (2)   
   Pfam (2)   
All databases (195)   

Download RDF
DBGET integrated database retrieval system