KEGG   Homo sapiens (human): 57379
Entry
57379             CDS       T01001                                 
Symbol
AICDA, AID, ARP2, CDA2, HEL-S-284, HIGM2
Name
(RefSeq) activation induced cytidine deaminase
  KO
K10989  activation-induced cytidine deaminase [EC:3.5.4.38]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04672  Intestinal immune network for IgA production
hsa05340  Primary immunodeficiency
Disease
H00086  Hyper IgM syndromes, autosomal recessive type
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04672 Intestinal immune network for IgA production
    57379 (AICDA)
 09160 Human Diseases
  09163 Immune disease
   05340 Primary immunodeficiency
    57379 (AICDA)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.38  single-stranded DNA cytosine deaminase
     57379 (AICDA)
SSDB
Motif
Pfam: APOBEC_N NAD1 APOBEC2 NAD2 SNAD4 APOBEC3 APOBEC_C APOBEC4_like APOBEC4 APOBEC1 RbcX
Other DBs
NCBI-GeneID: 57379
NCBI-ProteinID: NP_065712
OMIM: 605257
HGNC: 13203
Ensembl: ENSG00000111732
UniProt: Q9GZX7 Q546Y9 Q7Z599
Structure
Position
12:complement(8602170..8612859)
AA seq 198 aa
MDSLLMNRRKFLYQFKNVRWAKGRRETYLCYVVKRRDSATSFSLDFGYLRNKNGCHVELL
FLRYISDWDLDPGRCYRVTWFTSWSPCYDCARHVADFLRGNPNLSLRIFTARLYFCEDRK
AEPEGLRRLHRAGVQIAIMTFKDYFYCWNTFVENHERTFKAWEGLHENSVRLSRQLRRIL
LPLYEVDDLRDAFRTLGL
NT seq 597 nt   +upstreamnt  +downstreamnt
atggacagcctcttgatgaaccggaggaagtttctttaccaattcaaaaatgtccgctgg
gctaagggtcggcgtgagacctacctgtgctacgtagtgaagaggcgtgacagtgctaca
tccttttcactggactttggttatcttcgcaataagaacggctgccacgtggaattgctc
ttcctccgctacatctcggactgggacctagaccctggccgctgctaccgcgtcacctgg
ttcacctcctggagcccctgctacgactgtgcccgacatgtggccgactttctgcgaggg
aaccccaacctcagtctgaggatcttcaccgcgcgcctctacttctgtgaggaccgcaag
gctgagcccgaggggctgcggcggctgcaccgcgccggggtgcaaatagccatcatgacc
ttcaaagattatttttactgctggaatacttttgtagaaaaccacgaaagaactttcaaa
gcctgggaagggctgcatgaaaattcagttcgtctctccagacagcttcggcgcatcctt
ttgcccctgtatgaggttgatgacttacgagacgcatttcgtactttgggactttga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (9)   
   OC (1)   
Protein sequence (7)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (55)   
   RefSeq(nuc) (3)   
   GenBank (26)   
   EMBL (26)   
3D Structure (5)   
   PDB (5)   
Protein domain (11)   
   Pfam (11)   
All databases (102)   

Download RDF
DBGET integrated database retrieval system