KEGG   Homo sapiens (human): 57449
Entry
57449             CDS       T01001                                 
Symbol
PLEKHG5, ARHGEF45, CMTRIC, DSMA4, GEF720, HMNR4, Syx, Tech
Name
(RefSeq) pleckstrin homology and RhoGEF domain containing G5
  KO
K19464  pleckstrin homology domain-containing family G member 5
Organism
hsa  Homo sapiens (human)
Pathway
hsa05200  Pathways in cancer
Disease
H00264  Charcot-Marie-Tooth disease
H00856  Distal hereditary motor neuropathies
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    57449 (PLEKHG5)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04990 Domain-containing proteins not elsewhere classified [BR:hsa04990]
    57449 (PLEKHG5)
Domain-containing proteins not elsewhere classified [BR:hsa04990]
 Pleckstrin homology (PH) domain-containing proteins
  Other PH domain-containing proteins
   57449 (PLEKHG5)
SSDB
Motif
Pfam: RhoGEF PH_10 PH_16 PH_5 PH_13 PH
Other DBs
NCBI-GeneID: 57449
NCBI-ProteinID: NP_001036129
OMIM: 611101
HGNC: 29105
Ensembl: ENSG00000171680
UniProt: O94827
Position
1:complement(6467122..6520092)
AA seq 1006 aa
MHYDGHVRFDLPPQGSVLARNVSTRSCPPRTSPAVDLEEEEEESSVDGKGDRKSTGLKLS
KKKARRRHTDDPSKECFTLKFDLNVDIETEIVPAMKKKSLGEVLLPVFERKGIALGKVDI
YLDQSNTPLSLTFEAYRFGGHYLRVKAPAKPGDEGKVEQGMKDSKSLSLPILRPAGTGPP
ALERVDAQSRRESLDILAPGRRRKNMSEFLGEASIPGQEPPTPSSCSLPSGSSGSTNTGD
SWKNRAASRFSGFFSSGPSTSAFGREVDKMEQLEGKLHTYSLFGLPRLPRGLRFDHDSWE
EEYDEDEDEDNACLRLEDSWRELIDGHEKLTRRQCHQQEAVWELLHTEASYIRKLRVIIN
LFLCCLLNLQESGLLCEVEAERLFSNIPEIAQLHRRLWASVMAPVLEKARRTRALLQPGD
FLKGFKMFGSLFKPYIRYCMEEEGCMEYMRGLLRDNDLFRAYITWAEKHPQCQRLKLSDM
LAKPHQRLTKYPLLLKSVLRKTEEPRAKEAVVAMIGSVERFIHHVNACMRQRQERQRLAA
VVSRIDAYEVVESSSDEVDKLLKEFLHLDLTAPIPGASPEETRQLLLEGSLRMKEGKDSK
MDVYCFLFTDLLLVTKAVKKAERTRVIRPPLLVDKIVCRELRDPGSFLLIYLNEFHSAVG
AYTFQASGQALCRGWVDTIYNAQNQLQQLRAQEPPGSQQPLQSLEEEEDEQEEEEEEEEE
EEEGEDSGTSAASSPTIMRKSSGSPDSQHCASDGSTETLAMVVVEPGDTLSSPEFDSGPF
SSQSDETSLSTTASSATPTSELLPLGPVDGRSCSMDSAYGTLSPTSLQDFVAPGPMAELV
PRAPESPRVPSPPPSPRLRRRTPVQLLSCPPHLLKSKSEASLLQLLAGAGTHGTPSAPSR
SLSELCLAVPAPGIRTQGSPQEAGPSWDCRGAPSPGSGPGLVGCLAGEPAGSHRKRCGDL
PSGASPRVQPEPPPGVSAQHRKLTLAQLYRIRTTLLLNSTLTASEV
NT seq 3021 nt   +upstreamnt  +downstreamnt
atgcattatgatgggcatgtccgcttcgaccttcccccacaaggctctgtgctggcccgg
aacgtgtccacccggtcatgcccgccgcgcaccagccccgcagtggacttggaggaggag
gaggaggagagctctgtggatggcaaaggggaccggaagagcacaggcctgaaactctcc
aagaagaaagcaaggaggagacacacggatgacccaagcaaggaatgcttcactctgaaa
tttgacctgaatgtggacattgagacagagatcgtcccagccatgaagaagaagtcactg
ggggaggtgctgctgcctgtatttgaaaggaagggcattgcgctgggcaaagtggacatc
tacctggaccagtccaacacacccctgtccctcaccttcgaggcctacaggttcggggga
cactaccttcgtgtcaaagccccagccaagcctggagatgagggcaaggtggagcagggc
atgaaggactccaagtccctgagtttgccgattctgcggccagctgggaccgggcccccc
gccctggagcgtgtggacgcccagagccgccgggagagcctggacatcttggcccctggc
cgccgccgcaagaacatgtcggagttcctgggggaggcgagcatccccgggcaggagccc
cccacgccctccagctgctctctgcccagcggcagcagtggcagcaccaacactggcgac
agctggaagaaccgggcggccagtcgcttcagcggctttttcagctccggccccagcacc
agcgcctttggccgggaggtagacaagatggagcagctggagggcaagctgcacacctac
agcctcttcgggctgcccaggctgccccgggggctgcgcttcgaccatgactcctgggag
gaggagtacgatgaagacgaggatgaggacaatgcctgcctgaggctggaggacagctgg
cgggagctcattgatgggcatgagaagctgacccggcggcagtgccaccagcaggaggcg
gtgtgggagctgctgcacacggaggcctcctacatcaggaaactgcgggtgatcatcaac
ctgttcctgtgctgcctcctgaacctgcaagagtcagggctgctgtgtgaggtggaggcg
gagcgcctgttcagcaacatcccggagatcgcgcagctgcaccgcaggctgtgggctagc
gtgatggcgccggtgctggagaaggcgcggcgcacgcgagcgctgctacagcccggggac
ttcctcaaaggcttcaagatgttcggctcgctcttcaagccctacatccgctactgcatg
gaggaggagggctgcatggagtacatgcgcggcctgctgcgcgacaacgacctcttccgg
gcctacatcacgtgggcggagaagcacccacagtgccagaggctgaagctgagcgacatg
ctggccaaaccccaccagcggctcaccaagtacccgctgctgctcaagtcggtgctgagg
aagaccgaggagccgcgcgccaaggaggccgtcgtcgccatgatcggctccgtggagcgc
ttcatccaccacgtgaacgcgtgcatgcggcagcggcaggagcggcagcggctggcggcc
gtggtgagccgcatcgacgcctacgaggtggtggaaagcagcagcgacgaagtggacaag
ctcctgaaggaatttctgcacctggacttgacagcgcccatccctggcgcctccccggag
gagacgcggcagctgctgctggaggggagcctgaggatgaaggaggggaaggacagcaag
atggatgtgtactgcttcctcttcacggatctgctgttggtgaccaaagcagtgaagaag
gcagagaggaccagggtcatcaggccacccctgctcgtggacaagattgtgtgccgggag
ctacgggaccctgggtccttcctccttatctacctgaatgagtttcacagtgctgtaggg
gcctacacgttccaggccagtggccaggccttgtgccgtggctgggtggacaccatttac
aatgcccagaaccagctgcaacagctgcgtgcacaggagcccccaggcagtcagcagccc
ctgcagagcctggaagaggaggaggatgagcaggaggaggaagaggaggaggaggaggag
gaggaggaaggcgaggacagtggcacttcagctgccagctcccctaccatcatgcggaaa
agcagcggcagccccgactctcagcactgtgcctcagatggctccacggagaccctggcc
atggttgtggtagagcctggggacacgctgtcctcccccgagttcgacagcggtcctttc
agctcccagtctgatgagacctctctcagcaccactgcctcatctgccacgcccaccagt
gagctgctgcccctgggtccggtggacggccgctcctgctccatggactctgcctacggc
accctctccccaacctccttacaagactttgtggccccaggcccaatggcagagctagtg
cctcgggccccagagtccccacgagttccttcccctccaccctcgccccgtctccgccgc
cgcacccctgtccagctgttgagctgcccgccccacctgctcaagtctaagtccgaggcc
agcctcctccagctgctggcaggggctggcacccatgggacaccctctgcccccagccgc
agcctgtcagagctctgcctggctgttccagccccaggtattaggactcagggctcccct
caggaagctgggcccagctgggattgccgaggggcccctagccctggcagcggtcctggg
ctagtcggctgcctggccggggaacctgcaggctcccacaggaagaggtgtggagacctg
ccctcgggggcctctcccagggtccagcctgagcccccaccaggggtctctgcccagcac
aggaagctgaccctggcccagctctaccgaatcaggaccaccctgctgcttaactccacg
ctcactgcctcggaggtctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (5)   
   KEGG DISEASE (2)   
   OMIM (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (36)   
   KEGG ORTHOLOGY (1)   
   RefGene (26)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (10)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (8)   
DNA sequence (54)   
   RefSeq(nuc) (8)   
   GenBank (23)   
   EMBL (23)   
Protein domain (6)   
   Pfam (6)   
All databases (115)   

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