KEGG   Homo sapiens (human): 57506
Entry
57506             CDS       T01001                                 
Symbol
MAVS, CARDIF, IPS-1, IPS1, VISA
Name
(RefSeq) mitochondrial antiviral signaling protein
  KO
K12648  mitochondrial antiviral-signaling protein
Organism
hsa  Homo sapiens (human)
Pathway
hsa04621  NOD-like receptor signaling pathway
hsa04622  RIG-I-like receptor signaling pathway
hsa04623  Cytosolic DNA-sensing pathway
hsa05160  Hepatitis C
hsa05161  Hepatitis B
hsa05162  Measles
hsa05164  Influenza A
hsa05168  Herpes simplex virus 1 infection
hsa05169  Epstein-Barr virus infection
hsa05171  Coronavirus disease - COVID-19
Network
nt06162  Hepatitis B virus (HBV)
nt06163  Hepatitis C virus (HCV)
nt06165  Epstein-Barr virus (EBV)
nt06168  Herpes simplex virus 1 (HSV-1)
nt06169  Measles virus (MV)
nt06170  Influenza A virus (IAV)
nt06171  SARS coronavirus 2 (SARS-CoV-2)
nt06263  Hepatocellular carcinoma
nt06519  RLR signaling
  Element
N00268  HBV HBx to RIG-I-like receptor signaling pathway
N00271  HCV NS3/4A to RIG-I-like receptor signaling pathway
N00469  RIG-I-IRF7/3 signaling pathway
N00685  MV V to RIG-I-IRF7/3 signaling pathway
N00688  RIG-I-NFKB signaling pathway
N00732  IAV PB1-F2/PB2 to RIG-I-like receptor signaling pathway
N01308  MDA5-IRF7/3 signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    57506 (MAVS)
   04622 RIG-I-like receptor signaling pathway
    57506 (MAVS)
   04623 Cytosolic DNA-sensing pathway
    57506 (MAVS)
 09160 Human Diseases
  09172 Infectious disease: viral
   05161 Hepatitis B
    57506 (MAVS)
   05160 Hepatitis C
    57506 (MAVS)
   05171 Coronavirus disease - COVID-19
    57506 (MAVS)
   05164 Influenza A
    57506 (MAVS)
   05162 Measles
    57506 (MAVS)
   05168 Herpes simplex virus 1 infection
    57506 (MAVS)
   05169 Epstein-Barr virus infection
    57506 (MAVS)
SSDB
Motif
Pfam: CARD_2
Other DBs
NCBI-GeneID: 57506
NCBI-ProteinID: NP_065797
OMIM: 609676
HGNC: 29233
Ensembl: ENSG00000088888
UniProt: Q7Z434
Structure
Position
20:3846834..3876118
AA seq 540 aa
MPFAEDKTYKYICRNFSNFCNVDVVEILPYLPCLTARDQDRLRATCTLSGNRDTLWHLFN
TLQRRPGWVEYFIAALRGCELVDLADEVASVYQSYQPRTSDRPPDPLEPPSLPAERPGPP
TPAAAHSIPYNSCREKEPSYPMPVQETQAPESPGENSEQALQTLSPRAIPRNPDGGPLES
SSDLAALSPLTSSGHQEQDTELGSTHTAGATSSLTPSRGPVSPSVSFQPLARSTPRASRL
PGPTGSVVSTGTSFSSSSPGLASAGAAEGKQGAESDQAEPIICSSGAEAPANSLPSKVPT
TLMPVNTVALKVPANPASVSTVPSKLPTSSKPPGAVPSNALTNPAPSKLPINSTRAGMVP
SKVPTSMVLTKVSASTVPTDGSSRNEETPAAPTPAGATGGSSAWLDSSSENRGLGSELSK
PGVLASQVDSPFSGCFEDLAISASTSLGMGPCHGPEENEYKSEGTFGIHVAENPSIQLLE
GNPGPPADPDGGPRPQADRKFQEREVPCHRPSPGALWLQVAVTGVLVVTLLVVLYRRRLH
NT seq 1623 nt   +upstreamnt  +downstreamnt
atgccgtttgctgaagacaagacctataagtatatctgccgcaatttcagcaatttttgc
aatgtggatgttgtagagattctgccttacctgccctgcctcacagcaagagaccaggat
cgactgcgggccacctgcacactctcagggaaccgggacaccctctggcatctcttcaat
acccttcagcggcggcccggctgggtggagtacttcattgcggcactgaggggctgtgag
ctagttgatctcgcggacgaagtggcctctgtctaccagagctaccagcctcggacctcg
gaccgtcccccagacccactggagccaccgtcacttcctgctgagaggccagggcccccc
acacctgctgcggcccacagcatcccctacaacagctgcagagagaaggagccaagttac
cccatgcctgtccaggagacccaggcgccagagtccccaggagagaattcagagcaagcc
ctgcagacgctcagccccagagccatcccaaggaatccagatggtggccccctggagtcc
tcctctgacctggcagccctcagccctctgacctccagcgggcatcaggagcaggacaca
gaactgggcagtacccacacagcaggtgcgacctccagcctcacaccatcccgtgggcct
gtgtctccatctgtctccttccagcccctggcccgttccacccccagggcaagccgcttg
cctggacccacagggtcagttgtatctactggcacctccttctcctcctcatcccctggc
ttggcctctgcaggggctgcagagggtaaacagggtgcagagagtgaccaggccgagcct
atcatctgctccagtggggcagaggcacctgccaactctctgccctccaaagtgcctacc
accttgatgcctgtgaacacagtggccctgaaagtgcctgccaacccagcatctgtcagc
acagtgccctccaagttgccaactagctcaaagccccctggtgcagtgccttctaatgcg
ctcaccaatccagcaccatccaaattgcccatcaactcaacccgtgctggcatggtgcca
tccaaagtgcctactagcatggtgctcaccaaggtgtctgccagcacagtccccactgac
gggagcagcagaaatgaggagaccccagcagctccaacacccgccggcgccactggaggc
agctcagcctggctagacagcagctctgagaataggggccttgggtcggagctgagtaag
cctggcgtgctggcatcccaggtagacagcccgttctcgggctgcttcgaggatcttgcc
atcagtgccagcacctccttgggcatggggccctgccatggcccagaggagaatgagtat
aagtccgagggcacctttgggatccacgtggctgagaaccccagcatccagctcctggag
ggcaaccctgggccacctgcggacccggatggcggccccaggccacaagccgaccggaag
ttccaggagagggaggtgccatgccacaggccctcacctggggctctgtggctccaggtg
gctgtgacaggggtgctggtagtcacactcctggtggtgctgtaccggcggcgtctgcac
tag

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (10)   
   KEGG PATHWAY (10)   
Network (16)   
   KEGG NETWORK (16)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (27)   
   KEGG ORTHOLOGY (1)   
   RefGene (14)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (7)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (64)   
   RefSeq(nuc) (4)   
   GenBank (30)   
   EMBL (30)   
3D Structure (10)   
   PDB (10)   
Protein domain (1)   
   Pfam (1)   
All databases (136)   

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