KEGG   Homo sapiens (human): 5754
Entry
5754              CDS       T01001                                 
Symbol
PTK7, CCK-4, CCK4
Name
(RefSeq) protein tyrosine kinase 7 (inactive)
  KO
K05127  PTK7 protein tyrosine kinase 7 [EC:2.7.10.1]
Organism
hsa  Homo sapiens (human)
Drug target
Cofetuzumab: D11119
Cofetuzumab pelidotin: D11118
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    5754 (PTK7)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    5754 (PTK7)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     5754 (PTK7)
Protein kinases [BR:hsa01001]
 Receptor tyrosine kinases (RTK)
  CCK family
   5754 (PTK7)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   5754 (PTK7)
SSDB
Motif
Pfam: Ig_3 I-set PK_Tyr_Ser-Thr Ig_2 ig Pkinase V-set C2-set_2 Ig_6 BiPBP_C C1-set
Other DBs
NCBI-GeneID: 5754
NCBI-ProteinID: NP_002812
OMIM: 601890
HGNC: 9618
Ensembl: ENSG00000112655
UniProt: Q13308
Structure
Position
6:43076314..43161715
AA seq 1070 aa
MGAARGSPARPRRLPLLSVLLLPLLGGTQTAIVFIKQPSSQDALQGRRALLRCEVEAPGP
VHVYWLLDGAPVQDTERRFAQGSSLSFAAVDRLQDSGTFQCVARDDVTGEEARSANASFN
IKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSS
KERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVLAPQDVVVARYE
EAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYR
CIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVTCLPPKGLPEPSVWWEHAG
VRLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKKPQD
SQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWYR
CMSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGREKPTIKWERAD
GSSLPEWVTDNAGTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVAVFITFKVEPER
TTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSG
RYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSPPPYKMIQTIGLSVGAAVAYIIAVL
GLMFYCKKRCKAKRLQKQPEGEEPEMECLNGGPLQNGQPSAEIQEEVALTSLGSGPAATN
KRHSTSDKMHFPRSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLVKSLQSKDEQQQ
LDFRRELEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQ
PLSTKQKVALCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVSALGLSKDVYNSEY
YHFRQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQ
AGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASALGDSTVDSKP
NT seq 3213 nt   +upstreamnt  +downstreamnt
atgggagctgcgcggggatccccggccagaccccgccggttgcctctgctcagcgtcctg
ctgctgccgctgctgggcggtacccagacagccattgtcttcatcaagcagccgtcctcc
caggatgcactgcaggggcgccgggcgctgcttcgctgtgaggttgaggctccgggcccg
gtacatgtgtactggctgctcgatggggcccctgtccaggacacggagcggcgtttcgcc
cagggcagcagcctgagctttgcagctgtggaccggctgcaggactctggcaccttccag
tgtgtggctcgggatgatgtcactggagaagaagcccgcagtgccaacgcctccttcaac
atcaaatggattgaggcaggtcctgtggtcctgaagcatccagcctcggaagctgagatc
cagccacagacccaggtcacacttcgttgccacattgatgggcaccctcggcccacctac
caatggttccgagatgggacccccctttctgatggtcagagcaaccacacagtcagcagc
aaggagcggaacctgacgctccggccagctggtcctgagcatagtgggctgtattcctgc
tgcgcccacagtgcttttggccaggcttgcagcagccagaacttcaccttgagcattgct
gatgaaagctttgccagggtggtgctggcaccccaggacgtggtagtagcgaggtatgag
gaggccatgttccattgccagttctcagcccagccacccccgagcctgcagtggctcttt
gaggatgagactcccatcactaaccgcagtcgccccccacacctccgcagagccacagtg
tttgccaacgggtctctgctgctgacccaggtccggccacgcaatgcagggatctaccgc
tgcattggccaggggcagaggggcccacccatcatcctggaagccacacttcacctagca
gagattgaagacatgccgctatttgagccacgggtgtttacagctggcagcgaggagcgt
gtgacctgccttccccccaagggtctgccagagcccagcgtgtggtgggagcacgcggga
gtccggctgcccacccatggcagggtctaccagaagggccacgagctggtgttggccaat
attgctgaaagtgatgctggtgtctacacctgccacgcggccaacctggctggtcagcgg
agacaggatgtcaacatcactgtggccactgtgccctcctggctgaagaagccccaagac
agccagctggaggagggcaaacccggctacttggattgcctgacccaggccacaccaaaa
cctacagttgtctggtacagaaaccagatgctcatctcagaggactcacggttcgaggtc
ttcaagaatgggaccttgcgcatcaacagcgtggaggtgtatgatgggacatggtaccgt
tgtatgagcagcaccccagccggcagcatcgaggcgcaagcccgtgtccaagtgctggaa
aagctcaagttcacaccaccaccccagccacagcagtgcatggagtttgacaaggaggcc
acggtgccctgttcagccacaggccgagagaagcccactattaagtgggaacgggcagat
gggagcagcctcccagagtgggtgacagacaacgctgggaccctgcattttgcccgggtg
actcgagatgacgctggcaactacacttgcattgcctccaacgggccgcagggccagatt
cgtgcccatgtccagctcactgtggcagtttttatcaccttcaaagtggaaccagagcgt
acgactgtgtaccagggccacacagccctactgcagtgcgaggcccagggggaccccaag
ccgctgattcagtggaaaggcaaggaccgcatcctggaccccaccaagctgggacccagg
atgcacatcttccagaatggctccctggtgatccatgacgtggcccctgaggactcaggc
cgctacacctgcattgcaggcaacagctgcaacatcaagcacacggaggcccccctctat
gtcgtggacaagcctgtgccggaggagtcggagggccctggcagccctcccccctacaag
atgatccagaccattgggttgtcggtgggtgccgctgtggcctacatcattgccgtgctg
ggcctcatgttctactgcaagaagcgctgcaaagccaagcggctgcagaagcagcccgag
ggcgaggagccagagatggaatgcctcaacggtgggcctttgcagaacgggcagccctca
gcagagatccaagaagaagtggccttgaccagcttgggctccggccccgcggccaccaac
aaacgccacagcacaagtgataagatgcacttcccacggtctagcctgcagcccatcacc
acgctggggaagagtgagtttggggaggtgttcctggcaaaggctcagggcttggaggag
ggagtggcagagaccctggtacttgtgaagagcctgcagagcaaggatgagcagcagcag
ctggacttccggagggagttggagatgtttgggaagctgaaccacgccaacgtggtgcgg
ctcctggggctgtgccgggaggctgagccccactacatggtgctggaatatgtggatctg
ggagacctcaagcagttcctgaggatttccaagagcaaggatgaaaaattgaagtcacag
cccctcagcaccaagcagaaggtggccctatgcacccaggtagccctgggcatggagcac
ctgtccaacaaccgctttgtgcataaggacttggctgcgcgtaactgcctggtcagtgcc
cagagacaagtgaaggtgtctgccctgggcctcagcaaggatgtgtacaacagtgagtac
taccacttccgccaggcctgggtgccgctgcgctggatgtcccccgaggccatcctggag
ggtgacttctctaccaagtctgatgtctgggccttcggtgtgctgatgtgggaagtgttt
acacatggagagatgccccatggtgggcaggcagatgatgaagtactggcagatttgcag
gctgggaaggctagacttcctcagcccgagggctgcccttccaaactctatcggctgatg
cagcgctgctgggccctcagccccaaggaccggccctccttcagtgagattgccagcgcc
ctgggagacagcaccgtggacagcaagccgtga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Disease (1)   
   OMIM (1)   
Drug (2)   
   KEGG DRUG (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (13)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (11)   
DNA sequence (68)   
   RefSeq(nuc) (14)   
   GenBank (27)   
   EMBL (27)   
3D Structure (1)   
   PDB (1)   
Protein domain (11)   
   Pfam (11)   
All databases (120)   

Download RDF
DBGET integrated database retrieval system