KEGG   Homo sapiens (human): 57572
Entry
57572             CDS       T01001                                 
Symbol
DOCK6, AOS2, ZIR1
Name
(RefSeq) dedicator of cytokinesis 6
  KO
K21852  dedicator of cytokinesis protein 6/7/8
Organism
hsa  Homo sapiens (human)
Disease
H01413  Adams-Oliver syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    57572 (DOCK6)
Membrane trafficking [BR:hsa04131]
 Others
  Rho GTPase associated proteins
   Rho guanine nucleotide exchange factors (GEFs)
    57572 (DOCK6)
SSDB
Motif
Pfam: DHR-2_Lobe_A DOCK-C2 DHR-2_Lobe_C DOCK_C-D_N DHR-2_Lobe_B
Other DBs
NCBI-GeneID: 57572
NCBI-ProteinID: NP_065863
OMIM: 614194
HGNC: 19189
Ensembl: ENSG00000130158
UniProt: Q96HP0 B7Z9U8
Position
19:complement(11199295..11262524)
AA seq 2047 aa
MAASERRAFAHKINRTVAAEVRKQVSRERSGSPHSSRRCSSSLGVPLTEVVEPLDFEDVL
LSRPPDAEPGPLRDLVEFPADDLELLLQPRECRTTEPGIPKDEKLDAQVRAAVEMYIEDW
VIVHRRYQYLSAAYSPVTTDTQRERQKGLPRQVFEQDASGDERSGPEDSNDSRRGSGSPE
DTPRSSGASSIFDLRNLAADSLLPSLLERAAPEDVDRRNETLRRQHRPPALLTLYPAPDE
DEAVERCSRPEPPREHFGQRILVKCLSLKFEIEIEPIFGILALYDVREKKKISENFYFDL
NSDSMKGLLRAHGTHPAISTLARSAIFSVTYPSPDIFLVIKLEKVLQQGDISECCEPYMV
LKEVDTAKNKEKLEKLRLAAEQFCTRLGRYRMPFAWTAVHLANIVSSAGQLDRDSDSEGE
RRPAWTDRRRRGPQDRASSGDDACSFSGFRPATLTVTNFFKQEAERLSDEDLFKFLADMR
RPSSLLRRLRPVTAQLKIDISPAPENPHFCLSPELLHIKPYPDPRGRPTKEILEFPAREV
YAPHTSYRNLLYVYPHSLNFSSRQGSVRNLAVRVQYMTGEDPSQALPVIFGKSSCSEFTR
EAFTPVVYHNKSPEFYEEFKLHLPACVTENHHLLFTFYHVSCQPRPGTALETPVGFTWIP
LLQHGRLRTGPFCLPVSVDQPPPSYSVLTPDVALPGMRWVDGHKGVFSVELTAVSSVHPQ
DPYLDKFFTLVHVLEEGAFPFRLKDTVLSEGNVEQELRASLAALRLASPEPLVAFSHHVL
DKLVRLVIRPPIISGQIVNLGRGAFEAMAHVVSLVHRSLEAAQDARGHCPQLAAYVHYAF
RLPGTEPSLPDGAPPVTVQAATLARGSGRPASLYLARSKSISSSNPDLAVAPGSVDDEVS
RILASKLLHEELALQWVVSSSAVREAILQHAWFFFQLMVKSMALHLLLGQRLDTPRKLRF
PGRFLDDITALVGSVGLEVITRVHKDVELAEHLNASLAFFLSDLLSLVDRGFVFSLVRAH
YKQVATRLQSSPNPAALLTLRMEFTRILCSHEHYVTLNLPCCPLSPPASPSPSVSSTTSQ
SSTFSSQAPDPKVTSMFELSGPFRQQHFLAGLLLTELALALEPEAEGAFLLHKKAISAVH
SLLCGHDTDPRYAEATVKARVAELYLPLLSIARDTLPRLHDFAEGPGQRSRLASMLDSDT
EGEGDIAGTINPSVAMAIAGGPLAPGSRASISQGPPTASRAGCALSAESSRTLLACVLWV
LKNTEPALLQRWATDLTLPQLGRLLDLLYLCLAAFEYKGKKAFERINSLTFKKSLDMKAR
LEEAILGTIGARQEMVRRSRERSPFGNPENVRWRKSVTHWKQTSDRVDKTKDEMEHEALV
EGNLATEASLVVLDTLEIIVQTVMLSEARESVLGAVLKVVLYSLGSAQSALFLQHGLATQ
RALVSKFPELLFEEDTELCADLCLRLLRHCGSRISTIRTHASASLYLLMRQNFEIGHNFA
RVKMQVTMSLSSLVGTTQNFSEEHLRRSLKTILTYAEEDMGLRDSTFAEQVQDLMFNLHM
ILTDTVKMKEHQEDPEMLIDLMYRIARGYQGSPDLRLTWLQNMAGKHAELGNHAEAAQCM
VHAAALVAEYLALLEDHRHLPVGCVSFQNISSNVLEESAISDDILSPDEEGFCSGKHFTE
LGLVGLLEQAAGYFTMGGLYEAVNEVYKNLIPILEAHRDYKKLAAVHGKLQEAFTKIMHQ
SSGWERVFGTYFRVGFYGAHFGDLDEQEFVYKEPSITKLAEISHRLEEFYTERFGDDVVE
IIKDSNPVDKSKLDSQKAYIQITYVEPYFDTYELKDRVTYFDRNYGLRTFLFCTPFTPDG
RAHGELPEQHKRKTLLSTDHAFPYIKTRIRVCHREETVLTPVEVAIEDMQKKTRELAFAT
EQDPPDAKMLQMVLQGSVGPTVNQGPLEVAQVFLAEIPEDPKLFRHHNKLRLCFKDFCKK
CEDALRKNKALIGPDQKEYHRELERNYCRLREALQPLLTQRLPQLMAPTPPGLRNSLNRA
SFRKADL
NT seq 6144 nt   +upstreamnt  +downstreamnt
atggctgcctccgagcgccgcgccttcgcgcacaagatcaacaggacggtggccgcagag
gtgcggaagcaggtgtcccgggaacgcagtggctccccccactccagcaggcgctgcagc
agctccctgggggtcccactgactgaagttgtcgagcccctggactttgaggatgtactt
ctgagccggccaccagatgctgagcccgggcccctcagggacctggtagaattcccagct
gatgacttggagctgctgctgcagccccgggaatgccggaccacggagcccgggatcccc
aaggatgaaaaactggatgcccaggtgagggccgcggtggagatgtatattgaggactgg
gtcattgtccacagaaggtatcagtacctgagtgcagcatacagccccgtcaccacagac
acacagcgggagcgacagaagggcctcccccgccaggtctttgagcaggatgcttctgga
gacgagaggtccggccctgaggactcgaatgactcccggcgtggctcgggctccccggaa
gacacccctcgaagcagtggtgcctctagcatcttcgacctgaggaacctggcagctgac
tcattgctgccctctctgctagagcgggcggccccagaagatgtggaccggcgcaatgaa
acccttcgacggcagcaccggcccccggccctgctcaccctctacccggcacctgacgag
gatgaagccgtggaacgctgtagccgcccagagccaccccgcgagcactttggacaaagg
atcttggtcaagtgtctgtcgctcaagttcgagattgaaattgagcccatctttgggatc
ttggctctgtatgatgtgcgggagaaaaagaagatctcggagaacttctacttcgacctg
aactcggactccatgaaggggctgcttcgggctcatggcacccaccctgccatctccacc
ctggcccgctctgccatcttctctgtgacctacccctcacctgacatcttcctggtcatc
aagttggagaaggtgcttcagcaaggggacatcagtgagtgctgtgagccttacatggtg
ttgaaagaagtggacacagccaagaacaaagagaagctagagaagctgcgcctggcggcc
gagcagttctgcacccgcctgggccgctaccgcatgcccttcgcctggacggccgtgcac
ttggccaacatcgtgagcagcgctgggcagctggaccgggactctgactcggagggcgag
cgccggccagcctggacagaccgccgccgtcgggggccccaggaccgggcgagtagtggg
gacgacgcctgcagcttctctggcttccgtccagccacgctaactgtcacaaacttcttt
aagcaggaggctgagcgactcagtgacgaggacctcttcaagttcctggctgacatgagg
cgcccgtcgtccctgctgcggcgactacgtcctgtgactgcccagctcaagatcgacatt
tctccggctcctgaaaatccccacttctgcctctcccctgagctgcttcatatcaagccc
tacccggaccccaggggccggcccaccaaggagattctggagttccccgcccgcgaagtc
tatgccccccataccagctacaggaacctgctgtacgtgtacccgcacagcctcaacttc
agcagccgccagggctccgtgcgcaaccttgctgtgcgagtgcagtacatgacaggcgag
gaccccagccaggctctgccggtcatctttggcaagtccagctgcagtgaatttacccgc
gaggccttcacaccggtggtctaccataacaagtcccccgagttctacgaggagttcaag
ctgcatcttccagcctgcgtgacagagaaccatcacctgctgttcaccttctaccatgtc
agctgccagccccggccgggcactgccctggagacacccgtgggctttacttggatccca
ctgctgcagcacgggcgcctgaggaccggccccttctgtctcccagtgtctgtggaccag
ccgccgcccagctattccgtgctcacacccgatgtggcgcttccgggcatgcgctgggtg
gacggtcacaagggcgtgttcagtgtggagctcacagccgtgtcctctgtgcacccccag
gacccctacctggacaaattcttcaccctggtgcacgtcctggaggagggagccttccca
ttccggctcaaggacactgtgctgagcgagggcaacgtggagcaggagctgcgggccagt
cttgcagcactgcgcctggccagccccgaaccccttgtggccttctcccaccacgtgctg
gacaagctcgtgcgtctggtcatcaggcccccgatcatcagtggccagattgtgaacctg
ggccgtggagcctttgaagcaatggcccatgtagtcagccttgttcaccggagcctggag
gcagcccaggatgcccgcggtcactgcccacagctggctgcctacgtccactacgccttt
cgccttcctggcactgagcccagcctcccggatggggcccctccagtgacagtgcaggct
gccacactggcccgtggctctggtcgccccgcaagcctctacctggcgcgttccaagagc
atcagcagcagcaaccctgacctcgccgtggcccctggctctgtggatgacgaggtttcc
cgcatcctggccagcaagctgcttcacgaggagctggctctgcagtgggtggtcagcagc
agtgccgtacgcgaggccatcctccagcacgcctggttcttcttccagctcatggtgaag
agtatggcgctgcacctgctgcttggccagcgactagacacaccccgcaagctgcgcttc
cccggacgcttcctggacgacatcactgccttggtgggctctgtgggcctggaggtcatc
acccgtgtccacaaggatgtggagctggccgagcacctcaacgccagcctggctttcttc
ctcagtgaccttctgtccctggtggaccggggctttgtcttcagcctggtccgggcccac
tacaagcaggtggccacgcggctccagtcgtcccctaatccagcagccctgctgaccctg
cgcatggaattcacccgcatcctgtgcagccacgagcactacgtgaccctcaacctcccc
tgctgccccctgtcacctccagcctcgccctccccctctgtgtcctccaccacctcccag
agctccaccttctccagccaagccccggaccccaaggtgaccagcatgttcgaactgagt
ggaccattccggcagcagcacttcctagctgggctcctgctgacggagctggcactggcc
ctcgaacctgaggctgaaggggcattcctgttgcacaagaaggccatcagtgctgtgcac
agcctgctatgtggccatgacactgacccccgctacgccgaggccactgtgaaggctcgt
gtggccgagctgtacctgccactgctatcgattgcacgggataccttgccacggctgcat
gactttgctgagggcccaggtcagcggtcaagactggcctcaatgcttgactcagacaca
gaaggcgaaggggacattgcgggtaccatcaacccctctgtggccatggccattgctggt
ggccccctagcccctggctcccgggccagcatctcccaggggccaccaacggcttctcgc
gcaggctgtgccctctctgctgagtcaagccggaccttgctggcgtgtgtgctgtgggtg
ctgaaaaacaccgagccggcgctcctgcagcgctgggccactgacctgacactcccccag
ctgggacgtctgttggatttgctgtacctttgcctagctgcctttgagtacaaggggaaa
aaggcctttgaacgcatcaacagcctcacattcaaaaaatctctggatatgaaggcgcgg
ctagaggaagccattctgggtaccatcggagctcgacaagaaatggttcggcgaagtcgt
gagaggagcccgtttgggaatccggagaatgtgcgctggcggaagagcgtcacacactgg
aagcaaacctcagaccgcgtggacaagaccaaggatgaaatggaacacgaggccttggtg
gaagggaacctggcaaccgaggcaagcctagtggttctggacacactggagatcatcgtg
cagacggtgatgctttcagaagcccgggagagcgtcttgggggcagtgctgaaggttgtg
ctgtacagcctgggcagtgcccagagtgccctcttcttgcagcatggcctggccacccag
agggcccttgtgtccaagttcccggagctgctgttcgaggaggacacggagctgtgtgcc
gacctgtgcctgaggctcctacgacactgtggcagccgcatcagcaccatccgcacgcac
gccagcgcctcgctgtacctgctcatgcgacagaacttcgagatcggccacaactttgcc
cgtgtgaagatgcaggtcaccatgtctctctcgtccctggtggggacgacgcagaacttc
agtgaagagcacctgcgacgttcactcaaaaccatcctcacctatgctgaggaggacatg
gggctgcgggacagcaccttcgcagagcaggtccaggacctgatgttcaacctgcacatg
atcctgacggacacggtgaagatgaaggaacaccaggaggaccctgagatgctcatcgac
ctcatgtacagaattgcccggggctaccagggctcaccggaccttcggctgacctggttg
cagaacatggccgggaagcacgcggagctgggcaaccacgccgaggccgcccagtgcatg
gtgcacgcggccgccctcgtggctgagtacctcgccctgctcgaggaccaccgccacctg
cccgtgggctgcgtttccttccagaacatctcatccaacgtgctagaggagtccgccatc
tccgacgacatcctgtcgcccgacgaggagggcttctgctccgggaagcacttcactgag
ctggggctggtagggttgctggaacaggcagccggctacttcaccatgggcgggctctac
gaggcggtgaatgaggtctacaagaacctcatccccatcctggaagcccaccgtgactac
aagaagctggccgcggtgcacggcaaactgcaggaggccttcaccaagatcatgcaccag
agttccggctgggagcgcgtgttcgggacgtatttccgcgtgggcttctacggcgcccac
ttcggtgacctggatgagcaggagtttgtgtacaaggagccatcgatcacgaagctggca
gagatctcacaccggctggaggagttctacacggagagatttggcgacgacgtcgttgag
attatcaaagactctaaccctgtggacaagtccaagcttgactcacaaaaggcctacatc
cagatcacgtatgtggaaccgtactttgatacctacgagctcaaggaccgggtgacctac
tttgaccgcaactatgggcttcgcacattcctgttctgcacgccgttcacgccggatggg
cgcgcacacggggagctgcccgagcaacacaagcgtaagacgctgctcagcaccgaccac
gccttcccctacatcaagactcgcatccgtgtgtgccaccgggaggagacggtgctgacg
ccagtggaggtggccatcgaggacatgcagaagaagacacgggagctggcctttgccacc
gagcaggacccaccagatgctaagatgctacagatggtgcttcagggctctgtagggccc
accgtgaaccagggtcccctggaggtggcccaggtgtttttagcagagatcccggaagac
cccaagctcttccggcatcacaacaaattgcggctctgcttcaaggacttctgcaagaaa
tgtgaggatgcgctgcggaaaaataaggccctgattgggccggaccagaaggagtaccac
cgtgagctggagcgcaactactgccgcctgcgggaggctctgcagcccctgcttacccag
cgcctgccccagctgatggcacccaccccacccggcctcaggaactccttgaacagagca
agtttccgaaaggcagacctctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (30)   
   KEGG ORTHOLOGY (1)   
   RefGene (21)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (23)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (20)   
DNA sequence (52)   
   RefSeq(nuc) (20)   
   GenBank (16)   
   EMBL (16)   
Protein domain (5)   
   Pfam (5)   
All databases (116)   

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